Fig. 1. The network of interaction between FMDV proteins and DEGs in 3 hpi (A), 6 hpi (B), 12 hpi (C). The green circle indicates FMDV proteins and the others are DEGs among swine (Sus scrofa) proteins. The purple border of the diamond indicates DEGs that were significantly expressed over each FMDV infection time (6 hpi and 12 hpi). A total of 156 direct interactions were predicted. The lines indicates the predicted interaction. The thick lines are predicted with structure- based methods and the others are predicted with sequence-based methods.
Fig. 2. The linkage of 42 gene ontology terms and 43 related genes (red). The kappa score was set to 0.4 (default) and the network only showed pathways with p-value less than 0.05. The 11 representative terms (total 11 colors) which are merged as redundant groups with >50.0% sharing genes were highlighted.
Table 1. The top 10 canonical pathways by significantly up-regulated genes in 6 hpi
Table 2. The top 10 canonical pathways by significantly down-regulated genes in 6 hpi
Table 3. The top 10 canonical pathways by significantly up-regulated genes in 12 hpi
Table 4. The top 10 canonical pathways by significantly down-regulated genes in 12 hpi
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