Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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Epidemiological Features of Human Cases After Bites/Scratches From Rabies-suspected Animals in Zenica-Doboj Canton, Bosnia and Herzegovina

  • Uzunovic, Selma (Department for Clinical Microbiology, Institute for Health and Food Safety Zenica) ;
  • Skomorac, Muhamed (Department for Epidemiology, Institute for Health and Food Safety Zenica) ;
  • Basic, Fatima (Department for Epidemiology, Institute for Health and Food Safety Zenica) ;
  • Mijac-Music, Ivona (Department for Epidemiology, Institute for Health and Food Safety Zenica)
  • Received : 2018.10.31
  • Accepted : 2019.04.02
  • Published : 2019.05.31
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Abstract

Objectives: To determine the epidemiological features of patients and animals after bites/scratches from rabies-suspected animals in Zenica-Doboj Canton, Bosnia and Herzegovina. Methods: Data from all patients (and the causative animals) admitted to the Antirabies Service of the Institute for Health and Food Safety Zenica in the 2009-2017 period were analyzed, including age, sex, anatomical site of the bite/scratch, animal type (stray/owned/wildlife), veterinary observations of the animal, and whether antirabies post-exposure prophylaxis (PEP) was indicated and/or administered. Results: In total, 1716 patients were admitted. Bites/scratches were most frequently recorded during April and May (n=181, 10.5% and n=163, 9.5%, respectively). The persons admitted were mostly from the Zenica municipality (n=1278, 74.5%; incidence: 11.55/1000), which is 66.6% urbanized. Males were more frequently represented (n=1089, 63.6%). The patients were mostly 50-64 and 25-49 years of age (n=425, 24.7% and n=390, 22.7%, respectively). Dog bites were the most common cause (n=1634, 95.1%, of which n=1258, 77.0% were caused by stray dogs). PEP was indicated for 997 (58.1%) patients. Only 340 (19.9%) animals underwent veterinary observations (3.1% of stray and 76.1% of owned animals). The largest number of injuries were presented at lower extremities, 1044 (60.8%) cases. Conclusions: Zenica-Doboj Canton is a rabies-free region. Due to the high rate of stray animals not undergoing veterinary observations, the non-existence of a unique dog registry, and the consequent lack of information about stray animals in terms of number, vaccination, neutering, and euthanasia, there is an urgent need for improving the prevention and control of rabies within the One Health framework.

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References

  1. Sharafi AC, Tarrahi MJ, Saki M, Sharafi MM, Nasiri E, Mokhayeri H. Epidemiological study of animal bites and rabies in Lorestan Province in west of Iran during 2004-2014 for preventive purposes. Int J Prev Med 2016;7:104. https://doi.org/10.4103/2008-7802.190090
  2. Dimaano EM, Scholand SJ, Alera MT, Belandres DB. Clinical and epidemiological features of human rabies cases in the Philippines: a review from 1987 to 2006. Int J Infect Dis 2011;15(7):e495-e499. https://doi.org/10.1016/j.ijid.2011.03.023
  3. Lee HS, Thiem VD, Anh DD, Duong TN, Lee M, Grace D, et al. Geographical and temporal patterns of rabies post exposure prophylaxis (PEP) incidence in humans in the Mekong River Delta and Southeast Central Coast regions in Vietnam from 2005 to 2015. PLoS One 2018;13(4):e0194943. https://doi.org/10.1371/journal.pone.0194943
  4. World Health Organization. Human rabies: 2016 updates and call for data. Wkly Epidemiol Rec 2017;92(7):77-86.
  5. WHO Collaborating Centre for Rabies Surveillance and Research. Information surveillance report. Rabies Bull Eur 2013;37(2):3-24.
  6. World Health Organization. Rabies vaccines. WHO position paper. Wkly Epidemiol Rec 2007;82(49-50):425-435.
  7. WHO Collaborating Centre for Rabies Surveillance and Research. Information surveillance report. Rabies Bull Eur 1977;1(1):1-2.
  8. Kodrnja E. Ten years of counteract against the rabies. Vet Arh 1959;29(5-6):132-144 (Serbian).
  9. Rukavina LJ, Vaupotic A, Forsek Z, Saptalenko J. Occurence of rabies in animals of the northeastern Bosnia with reference ot the factors suitable for the maintenance and spread of the infection. Vet Glas 1973;27(10):743-750 (Serbian).
  10. WHO Collaborating Centre for Rabies Surveillance and Research. Information surveillance report. Rabies Bull Eur 1977;1(2):10-11.
  11. Djuricic B, Petrovic M, Panjevic Dj, Valcic M. Epizootic situation of rabies in Yougoslavia in the period 1977-1987. Veterinarski Glasnik 1988;42(8):483-493 (Serbian).
  12. WHO Collaborating Centre for Rabies Surveillance and Research. Information surveillance report. Rabies Bull Eur 2001;25(3):3-32.
  13. Velic R, Bajrovic T, Zvizdic S, Velic L, Hamzic S. Genetic characterisation of rabies virus isolates in Bosnia and Herzegovina. Bosn J Basic Med Sci 2008;8(3):239-244. https://doi.org/10.17305/bjbms.2008.2925
  14. Government of Bosnia and Herzegovina. The Veterinary Law in Bosnia and Herzegovina; 2002 [cited 2018 Mar 20]. Available from: http://www.vet.gov.ba/pdffiles/Zakon_O_Vetrinarstvu/Veterinary%20Law.pdf.
  15. Government of Bosnia and Herzegovina. Decision on infectious diseases; 2003 [cited 2018 Mar 20]. Available from: http://extwprlegs1.fao.org/docs/pdf/bih148466.pdf (Bosnian).
  16. Government of Bosnia and Herzegovina. Legislative of protection of population from infectious diseases; 2005 [cited 2018 Mar 20]. Available from: http://www.fmoh.gov.ba/index.php/zakoni-i-strategije/zakoni/zakon-o-zastiti-stanovnistvaod-zaraznih-bolesti (Bosnian).
  17. Government of Bosnia and Herzegovina. Rulebook of infectious diseases reporting; 2012 [cited 2018 Mar 20]. Available from: http://www.zzjzfbih.ba/wp-content/uploads/2017/09/Pravilnik-o-prijavljivanju-Zaraznih-bolesti-101-2012-ilovepdf-compressed.pdf (Bosnian).
  18. Ren J, Gong Z, Chen E, Lin J, Lv H, Wang W, et al. Human rabies in Zhejiang Province, China. Int J Infect Dis 2015;38:77-82. https://doi.org/10.1016/j.ijid.2015.07.013
  19. Pasteur Institute. Rabies report of 1953-1991. Novi Sad: Pasteur Institute; 1992 (Serbian).
  20. Yin CP, Zhou H, Wu H, Tao XY, Rayner S, Wang SM, et al. Analysis on factors related to rabies epidemic in China from 2007-2011. Virol Sin 2012;27(2):132-143. https://doi.org/10.1007/s12250-012-3244-y
  21. Tenzin, Dhand NK, Ward MP. Patterns of rabies occurrence in Bhutan between 1996 and 2009. Zoonoses Public Health 2011;58(7):463-471. https://doi.org/10.1111/j.1863-2378.2011.01393.x
  22. Messenger SL, Smith JS, Rupprecht CE. Emerging epidemiology of bat-associated cryptic cases of rabies in humans in the United States. Clin Infect Dis 2002;35(6):738-747. https://doi.org/10.1086/342387
  23. Kassiri H, Kassiri A, Mosavi R, Jashireh A, Lotfi M. Prevalence rate and epidemiological determinants of animal bite in Ahvaz County, Khuzestan Province, Southwestern Iran. J Acute Dis 2014;3(1):51-55. https://doi.org/10.1016/S2221-6189(14)60011-1
  24. Wallace R, Etheart M, Ludder F, Augustin P, Fenelon N, Franka R, et al. The health impact of rabies in Haiti and recent developments on the path toward elimination, 2010-2015. Am J Trop Med Hyg 2017;97(4_Suppl):76-83.
  25. Nguyen HT, Tran CH, Dang AD, Tran HG, Vu TD, Pham TN, et al. Rabies vaccine hesitancy and deaths among pregnant and breastfeeding women - Vietnam, 2015-2016. MMWR Morb Mortal Wkly Rep 2018;67(8):250-252. https://doi.org/10.15585/mmwr.mm6708a4
  26. European Commission. Improvement of animal health control through the vaccination against rabies. IPA National Programme 2010 - Bosnia and Herzegovina. Fiche 14 "Animal Health" [cited 2018 May 30]. Available from: https://ec.europa.eu/neighbourhood-enlargement/sites/near/files/pdf/bosnia_and_herzegovina/ipa/2010/part-1/pf_14_ipa_2010_rabies_en.pdf.
  27. Mutinelli F, Stankov S, Hristovski M, Seimenis A, Theoharakou H, Vodopija I. Rabies in Italy, Yugoslavia, Croatia, Bosnia, Slovenia, Macedonia, Albania & Greece. In: King AA, editor. Historical perspective of rabies in Europe and the Mediterranean Basin: a testament to rabies by Dr Arthur A. King. Geneva: World Health Organization; 2004, p. 98-108.
  28. Katica M, Gradascevic N, Hadzimusic N, Obradovic Z, Mujkanovic R, Mestric E, et al. Widespread of stray dogs: methods for solving the problem in certain regions of Bosnia and Herzegovina. Int J Res Granthaalayah 2017;5(6):414-422.
  29. Millien MF, Pierre-Louis JB, Wallace R, Caldas E, Rwangabgoba JM, Poncelet JL, et al. Control of dog mediated human rabies in Haiti: no time to spare. PLoS Negl Trop Dis 2015;9(6):e000-3806.
  30. Gibson AD, Handel IG, Shervell K, Roux T, Mayer D, Muyila S, et al. The vaccination of 35,000 dogs in 20 working days using combined static point and door-to-door methods in Blantyre, Malawi. PLoS Negl Trop Dis 2016;10(7):e0004824. https://doi.org/10.1371/journal.pntd.0004824
  31. Mazeri S, Gibson AD, Meunier N, Bronsvoort BM, Handel IG, Mellanby RJ, et al. Barriers of attendance to dog rabies static point vaccination clinics in Blantyre, Malawi. PLoS Negl Trop Dis 2018;12(1):e0006159. https://doi.org/10.1371/journal.pntd.0006159
  32. Castillo-Neyra R, Brown J, Borrini K, Arevalo C, Levy MZ, Buttenheim A, et al. Barriers to dog rabies vaccination during an urban rabies outbreak: qualitative findings from Arequipa, Peru. PLoS Negl Trop Dis 2017;11(3):e0005460. https://doi.org/10.1371/journal.pntd.0005460
  33. Salyer SJ, Silver R, Simone K, Barton Behravesh C. Prioritizing zoonoses for global health capacity building-themes from one health zoonotic disease workshops in 7 countries, 2014-2016. Emerg Infect Dis 2017;23(Suppl 1):S55-S64.