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Do Blebs or Bullae on High-Resolution Computed Tomography Predict Ipsilateral Recurrence in Young Patients at the First Episode of Primary Spontaneous Pneumothorax?

  • Park, Sungjoon (Department of Thoracic and Cardiovascular Surgery, Inje University Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Jang, Hyo Jun (Department of Thoracic and Cardiovascular Surgery, Hanyang University Seoul Hospital) ;
  • Song, Ju Hoon (Department of Thoracic and Cardiovascular Surgery, Hanyang University Seoul Hospital) ;
  • Bae, So Young (Department of Thoracic and Cardiovascular Surgery, Hanyang University Seoul Hospital) ;
  • Kim, Hyuck (Department of Thoracic and Cardiovascular Surgery, Hanyang University Seoul Hospital) ;
  • Nam, Seung Hyuk (Department of Thoracic and Cardiovascular Surgery, Hanyang University Guri Hospital) ;
  • Lee, Jun Ho (Department of Thoracic and Cardiovascular Surgery, Hanyang University Seoul Hospital)
  • Received : 2018.09.17
  • Accepted : 2018.10.22
  • Published : 2019.04.05

Abstract

Background: The relationship between the size of bullae and pneumothorax recurrence is controversial. The aim of this study was to retrospectively evaluate the role of blebs or bullae in predicting ipsilateral recurrence in young patients experiencing their first episode of primary spontaneous pneumothorax (PSP) who underwent conservative treatment. Methods: A total of 299 cases of first-episode PSP were analyzed. The status of blebs or bullae was reviewed on high-resolution computed tomography (HRCT). The dystrophic severity score (DSS; range, 0 to 6 points) was calculated based on HRCT. Results: The 5-year recurrence rate was 38.2%. In univariate analysis, age (<20 years), body mass index (<$20kg/m^2$), a unilateral lesion, and intermediate risk (DSS 4 and 5) were associated with recurrence. Sex; smoking history; and the presence, number, and maximal size of blebs or bullae were not related to recurrence. In Cox regression, age and intermediate risk were independent risk factors for recurrence. High risk (DDS 6) was not an independent risk factor. Conclusion: The presence, number, and size of blebs or bullae did not affect ipsilateral recurrence. DSS failed to show a positive correlation between severity and recurrence. The decision to perform surgery in patients experiencing their first episode of PSP should not be determined by the severity of blebs and bullae.

Keywords

References

  1. Bobbio A, Dechartres A, Bouam S, et al. Epidemiology of spontaneous pneumothorax: gender-related differences. Thorax 2015;70:653-8. https://doi.org/10.1136/thoraxjnl-2014-206577
  2. Chambers A, Scarci M. In patients with first-episode primary spontaneous pneumothorax is video-assisted thoracoscopic surgery superior to tube thoracostomy alone in terms of time to resolution of pneumothorax and incidence of recurrence? Interact Cardiovasc Thorac Surg 2009;9:1003-8. https://doi.org/10.1510/icvts.2009.216473
  3. MacDuff A, Arnold A, Harvey J; BTS Pleural Disease Guideline Group. Management of spontaneous pneumothorax: British Thoracic Society pleural disease guideline 2010. Thorax 2010;65 Suppl 2:ii18-31.
  4. Baumann MH, Strange C, Heffner JE, et al. Management of spontaneous pneumothorax: an American College of Chest Physicians Delphi consensus statement. Chest 2001;119:590-602. https://doi.org/10.1378/chest.119.2.590
  5. Bintcliffe OJ, Hallifax RJ, Edey A, et al. Spontaneous pneumothorax: time to rethink management? Lancet Respir Med 2015;3:578-88. https://doi.org/10.1016/S2213-2600(15)00220-9
  6. Olesen WH, Katballe N, Sindby JE, et al. Surgical treatment versus conventional chest tube drainage in primary spontaneous pneumothorax: a randomized controlled trial. Eur J Cardiothorac Surg 2018;54:113-21. https://doi.org/10.1093/ejcts/ezy003
  7. Ouanes-Besbes L, Golli M, Knani J, et al. Prediction of recurrent spontaneous pneumothorax: CT scan findings versus management features. Respir Med 2007;101:230-6. https://doi.org/10.1016/j.rmed.2006.05.016
  8. Hansell DM, Bankier AA, MacMahon H, McLoud TC, Muller NL, Remy J. Fleischner Society: glossary of terms for thoracic imaging. Radiology 2008;246:697-722. https://doi.org/10.1148/radiol.2462070712
  9. Mitlehner W, Friedrich M, Dissmann W. Value of computer tomography in the detection of bullae and blebs in patients with primary spontaneous pneumothorax. Respiration 1992;59:221-7. https://doi.org/10.1159/000196062
  10. Smit HJ, Wienk MA, Schreurs AJ, Schramel FM, Postmus PE. Do bullae indicate a predisposition to recurrent pneumothorax? Br J Radiol 2000;73:356-9. https://doi.org/10.1259/bjr.73.868.10844859
  11. Noh D, Keum DY, Park CK. Outcomes of contralateral bullae in primary spontaneous pneumothorax. Korean J Thorac Cardiovasc Surg 2015;48:393-7. https://doi.org/10.5090/kjtcs.2015.48.6.393
  12. Casali C, Stefani A, Ligabue G, et al. Role of blebs and bullae detected by high-resolution computed tomography and recurrent spontaneous pneumothorax. Ann Thorac Surg 2013;95:249-55. https://doi.org/10.1016/j.athoracsur.2012.05.073
  13. Soler LM, Raymond SL, Larson SD, Taylor JA, Islam S. Initial primary spontaneous pneumothorax in children and adolescents: operate or wait? J Pediatr Surg 2018;53:1960-3. https://doi.org/10.1016/j.jpedsurg.2017.12.014
  14. Primavesi F, Jager T, Meissnitzer T, et al. First episode of spontaneous pneumothorax: CT-based scoring to select patients for early surgery. World J Surg 2016;40:1112-20. https://doi.org/10.1007/s00268-015-3371-3
  15. Martinez-Ramos D, Angel-Yepes V, Escrig-Sos J, Miralles-Tena JM, Salvador-Sanchis JL. Usefulness of computed tomography in determining risk of recurrence after a first episode of primary spontaneous pneumothorax: therapeutic implications. Arch Bronconeumol 2007;43:304-8.
  16. Vuong NL, Elshafay A, Thao LP, et al. Efficacy of treatments in primary spontaneous pneumothorax: a systematic review and network meta-analysis of randomized clinical trials. Respir Med 2018;137:152-66. https://doi.org/10.1016/j.rmed.2018.03.009
  17. Herrmann D, Klapdor B, Ewig S, Hecker E. Initial management of primary spontaneous pneumothorax with video- assisted thoracoscopic surgery: a 10-year experience. Eur J Cardiothorac Surg 2016;49:854-9. https://doi.org/10.1093/ejcts/ezv206
  18. Schnell J, Beer M, Eggeling S, et al. Management of spontaneous pneumothorax and post-interventional pneumothorax: German S3 guideline. Respiration 2018:1-33. https://doi.org/10.1159/000490179.
  19. Noh D, Lee S, Haam SJ, Paik HC, Lee DY. Recurrence of primary spontaneous pneumothorax in young adults and children. Interact Cardiovasc Thorac Surg 2015;21:195-9. https://doi.org/10.1093/icvts/ivv104

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