대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
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중증근무력증이 한의학적 치료로 개선된 임상 1례

A Case Study on the Alleviation of Symptom of a Myasthenia Gravis Patient after Korean Medicine Treatment

  • 배영춘 (원광대학교 한의과대학 사상체질의학교실) ;
  • 박수정 (우석대학교 한의과대학 사상체질의학교실)
  • Bae, Young-chun (Dept. of Sasang Constitutional Medicine, College of Korean Medicine, Wonkwang University) ;
  • Park, Soo-jung (Dept. of Sasang Constitutional Medicine, College of Korean Medicine, Woosuk University)
  • 투고 : 2019.02.26
  • 심사 : 2019.03.26
  • 발행 : 2019.03.30
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초록

Objective: The purpose of this study was to report on the alleviation of symptoms of a myasthenia gravis (MG) patient after Korean medicine treatment. Methods: A 39 year-old male patient who suffered from MG was examined. The patient was treated with herbal medicine, acupuncture, and pharmacopuncture. The Myasthenia Gravis Composite (MGC) scale and Myasthenia Gravis Activities of Daily Living (MG-ADL) profile were used to assess the change of MG symptoms after Korean medicine treatment. Results: The MGC and MG-ADL scores indicated significant improvement after 14 days of treatment. In addition, the degrees of fatigue, dyspepsia, vomiting, sweating, and dizziness were decreased. Conclusion: This study may suggest that Korean medicine treatment could be effective in treating the symptoms of MG.

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참고문헌

  1. Huang D, Liu L, Noren K, Xia S, Trifunovic J, Pirsknen R, et al. Genetic association of Ctla-4 to myasthenia gravis with thymoma. J Neuroimmunol 1998;88(1-2):192-8. https://doi.org/10.1016/S0165-5728(98)00119-2
  2. Aarli JA. Myasthenia gravis in the elderly: Is it different?. Ann N Y Acad Sci 2008;1132(1):238-43. https://doi.org/10.1196/annals.1405.040
  3. Kwon KH. MuSK antibody positive myasthenia gravis. J Korean EMG Electrodiagn Med 2012;14(1):10-6.
  4. Kim JY. Recent Advances in Myasthenia Gravis. J Korean EMG Electrodiagn Med 2013;15(2):59-63.
  5. Shin YI, Lee BR. The Literatural study on We Jeung. Hyehwa med 2000;9(1):102-23.
  6. Chen S, Xu MB, Zhou XL, Rong PQ, Jin TY, Zheng GQ. Chinese Herbal Medicine for Myasthenia Gravis: A Systematic Review and Meta-Analysis. Front Pharmacol 2018;9:969. https://doi.org/10.3389/fphar.2018.00969
  7. Yoon CB. The clinical study of Myasthenia Gravis. The Journal of Korean Oriental Medical Society 1996;17(1):190-211.
  8. Hong JH, Park JW, Kim JS, Jeon WH, Cho NH, Oh SW, et al. A Case of Myasthenia Gravis with Thymoma. The Journal of Oriental Chronic Diseases2000;6(1):27-32.
  9. Burns TM, Conaway MR, Sanders DB, Cutter GR, Sanders DB, Muscle Study Group. Construction of an efficient evaluative instrument for myasthenia gravis: The MG composite. Muscle and Nerve 2008;38(6):1553-62. https://doi.org/10.1002/mus.21185
  10. Muppidi S, Wolfe GI, Conaway M, Burns TM, the MG composite, MG QOL group. MG-ADL: Still a relevant outcome measure. Muscle and Nerve 2011;44(5):727-31. https://doi.org/10.1002/mus.22140
  11. Oh SJ. Muscle-specific receptor tyrosine kinase antibody positive myasthenia gravis current status. J Clin Neurol 2009;5(2):53-64. https://doi.org/10.3988/jcn.2009.5.2.53
  12. Zhang B, Tzartos JS, Belimezi M, Ragheb S, Bealmear B, Lewis RA, et al. Autoantibodies to lipoprotein-related protein 4 in patients with double-seronegative myasthenia gravis. Arch Neurol 2012;69(4):445-51. https://doi.org/10.1001/archneurol.2011.2393
  13. Higuchi O, Hamuro J, Motomura M, Yamanashi Y. Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis. Ann Neurol 2011;69(2):418-22. https://doi.org/10.1002/ana.22312
  14. Besinger UA, Toyka KV, Heninger K, Fateh -Moghadam A, Schumm F, Sandel P, et al. Long-term correlation of clinical course and acetylcholine receptor antibody in patients with myasthenia gravis. Ann N Y Acad Sci 1981;377(1):812-5. https://doi.org/10.1111/j.1749-6632.1981.tb33781.x
  15. Barohn RJ, McIntire D, Herbelin L, Wolfe GI, Nations S, Bryan WW. Reliability testing of the quantitative myasthenia gravis score. Ann N Y Acad Sci1998;841:769-72. https://doi.org/10.1111/j.1749-6632.1998.tb11015.x
  16. Lee EJ, Koh BH, Kim DR, Kim JY, Kim JW, Park SS, et al. Clinical Practice Guideline for Soyangin Disease of Sasang Constitutional Medicine: Overview. J Sasang Constitut Med 2014;26(3):213-23. https://doi.org/10.7730/JSCM.2014.26.3.213
  17. Shin MR, Joo JC, Lee EJ. Clinical Practice Guideline for Soyangin Disease of Sasang Constitutional Medicine: Yin-Depletion (Mangeum) Symptomatology. J Sasang Constitut Med 2014;26(3):251-61. https://doi.org/10.7730/JSCM.2014.26.3.251
  18. Yu JS, Lee EJ. Clinical Practice Guideline for Soyangin Disease of Sasang Constitutional Medicine: Yin-Deficit Diurnal-Heat (Eumheo-oyeol) symptomatology. J Sasang Constitut Med 2014;26(3):272-80. https://doi.org/10.7730/JSCM.2014.26.3.272
  19. Lee SK, Song IB. The Study about The Discourse on the Costitutional Symptoms and Diseases of Sasangin on the Dongyi Suse Bowon. J Sasang Constitute Med 1999;11(2):1-26.
  20. Lee JH, Lee EJ, Koh BH. The Study on the Clinical Meanings of Ordinary Symptoms and Developing Aspects of Present Symptoms according to the Ordinary Symptoms in the Soeumin Symptomatology. J Sasang Constitute Med 2012;24(3):17-33.
  21. Song AN, An JH, Choi EH, Park SJ, Kim KS, Lee SK. A Case study of Rectal Cancer Patient Treated with Dokhwaljihwang-tang. J Sasang Constitute Med2013;25(1):62-70. https://doi.org/10.7730/JSCM.2013.25.1.62
  22. Lee JW, Choi HM, Lim EC. A Case Study of Polyarthritis Treated with Dokhwaljihwang-tang. J Sasang Constitute Med 2017;29(4):369-75.
  23. Moon YH, Park HS. A Case of Psoriasis Treated with Soyangin Dokhwaljihwang-tang. J Sasang Constitute Med2015;27(1):171-7. https://doi.org/10.7730/JSCM.2015.27.1.171
  24. Kim SM, Kim HJ, Lee MJ, Shin YJ. Effects of Local and Da-am Acupuncture on Hypoadrenia and Chronic Low Back Pain. J Korean Oriental Med 2009;30(2):104-16.
  25. Kim BS, Baik YS. A Study on Treatment for Symptoms of Hypoadrenocorticism and Indicant of Kidney Jeonggyeok(腎正格). J Korean Medical Classics 2014;27(3):101-22. https://doi.org/10.14369/SKMC.2014.27.3.101
  26. Yook TH. Clinical Observation about the Extent of Improvement of Low Back Pain Patient through Mediacupuncture Therapy. The Journal of Korean Medicine1995;16(1):184-97.
  27. Choi BC, Ahn TW. Clinical comparison studies on 30 cases of Bell's palsy patient with postauricular pain by Anti-inflammatory pharmacopuncture & Acupuncture and Herbal therapy. The Journal of Daejeon Oriental Medicine2009;18(2):89-94.
  28. Korean Pharmacopuncture Institute Science Committee. Pharmacopuncture. Seoul: Elsvier Korea; 2011, p. 179.
  29. Kim SL, Hong KE. The clinical observations of 3 cases of metatarsal tendinitis treated with anti-inflammatory herbal acupuncture. Journal of Pharmacopuncture2007;10(1):157-62. https://doi.org/10.3831/KPI.2007.10.1.157
  30. Lee BH, Son JH. A Critical Review on Pain Measurements in Normal Men and Pain Patients. Korean Journal of Psychology 1996;15(1):163-88.