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Bioactive Characteristics of Sorghum Extract/Poly(vinyl alcohol) Composite Nanoweb Produced by Electrospinning

전기방사에 의해 제조된 수수 추출물 함유 폴리비닐알코올 복합 나노 섬유의 생리활성 특성

  • Lee, Hyun Ju (Korea Dyeing and Finishing Technology Institute) ;
  • Jeon, Jae Woo (Korea Dyeing and Finishing Technology Institute) ;
  • Jung, So Yeon (Department of Biofibers and Biomaterials Science, Kyungpook National University) ;
  • Choi, Jin Hyun (Department of Biofibers and Biomaterials Science, Kyungpook National University)
  • Received : 2019.11.20
  • Accepted : 2019.12.10
  • Published : 2019.12.27

Abstract

Sorghum is a rich source in phytochemicals, such as tannins, phenolic acids, anthocyanins, phytosterols and policosanols. Sorghum has been known to have antimicrobial, antiinflammatory, antioxidant properties. In this study, poly(vinyl alcohol)(PVA)-sorghum extract(SE) composite nanoweb was produced by electrospinning and its characteristics including bioactivities were investigated. The SE had antimicrobial and antiinflammatory activities as well as a reduced cytotoxicity. The PVA-SE nanoweb had a highly enhanced antimicrobial activity compared to PVA nanoweb. The amount of proinflammatory cytokine released from macrophages treated with the PVA-SE nanoweb was reduced. The PVA-SE nanoweb can be a potential candidate for medical and cosmeceutical materials providing antimicrobial and antiinflammatory activities with a low degree of cytotoxicity.

Keywords

References

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