Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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Scabies mimicking graft versus host disease in a hematopoietic cell transplant recipient

  • Kim, Dongsub (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Choi, Soo-Han (Department of Pediatrics, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Lee, Dong Youn (Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Juyoun (Department of Pediatrics, Samsung Medical Center) ;
  • Cho, Eunjoo (Department of Pediatrics, Samsung Medical Center) ;
  • Yoo, Keon Hee (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Koo, Hong Hoe (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Yae-Jean (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Received : 2018.10.24
  • Accepted : 2018.11.09
  • Published : 2018.11.15
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Abstract

Scabies is a highly contagious skin infestation caused by the mite, Sarcoptes scabiei var. hominis. Complex responses to scabies mites in the innate, humoral, and cellular immune systems can cause skin inflammation and pruritus. Diagnosis can be challenging because scabies resembles other common skin conditions. We report the first Korean case of scabies in a hematopoietic cell transplant (HCT) recipient, initially suspected of skin graft versus host disease (GVHD). A T-cell acute lymphocytic leukemia patient underwent a sibling-matched allogeneic HCT and developed pruritus after cell engraftment. Treatment for GVHD did not improve the symptoms. He was diagnosed with scabies 30 days after the onset of symptoms.

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References

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