생체재료학회지 (Biomaterials Research)

  • 제22권3호
  • /
  • Pages.202-209
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  • 2018
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  • 1226-4601(pISSN)
  • /
  • 2055-7124(eISSN)
한국생체재료학회 (Korean Society for Biomaterials)
권호 표지
DOI QR코드

DOI QR Code

Classification of gallstones using Fourier-transform infrared spectroscopy and photography

  • Ha, Byeong Jo (Department of Beauty and Cosmetics, College of Health Science, Eulji University) ;
  • Park, Sangsoo (Department of Biomedical Engineering, College of Health Science, Eulji University)
  • 투고 : 2018.04.26
  • 심사 : 2018.06.27
  • 발행 : 2018.09.30
⟨ 이전 논문 다음 논문 ⟩

초록

Background: Gallstones have conventionally been classified by gross inspection into 4 categories: cholesterol gallstones, black pigment (calcium bilirubinate) gallstones, brown gallstones, and mixed gallstones that contain both cholesterol and calcium bilirubinate. Classification using Fourier-transform infrared (FT-IR) spectroscopy supplements gross inspection; however, the issue of ambiguity in gallstone classification has not been fully addressed to date. Methods: Twenty-six gallstones obtained after surgical gallbladder removal were examined using FT-IR spectroscopy and digital photography, and classified into 6 gallstone groups according to characteristic FT-IR absorption bands. Results: FT-IR spectra of nine gallstones matched well with that of pure cholesterol, and the gallstones were thus classified as cholesterol stones. Twelve gallstones were classified as calcium bilirubinate stones as they showed characteristic absorption bands of calcium bilirubinate. However, the FT-IR spectra of these gallstones always showed a broad absorption band of bound water at $3600-2400\;cm^{-1}$. The other five gallstones were classified as mixed stones with combinations of cholesterol, calcium bilirubinate, and calcium carbonate. Conclusion: FT-IR spectroscopy is a powerful and convenient method for gallstone classification. Nevertheless, one should take serious note of the superposition of FT-IR absorption bands of different chemical components of gallstones including that of bound water.

키워드

과제정보

연구 과제 주관 기관 : Eulji university

참고문헌

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