Journal of Medicine and Life Science

Institute for Medical Science (제주대학교 의과학연구소)
권호 표지
DOI QR코드

DOI QR Code

Allergy tests in clinical practice

알레르기 검사의 실제

  • Lee, Jaechun (Department of Internal Medicine, Jeju National University School of Medicine)
  • 이재천 (제주대학교 의학전문대학원 내과학교실)
  • Received : 2018.04.23
  • Accepted : 2018.06.20
  • Published : 2018.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Allergy is conditions when a hypersensitivity reaction happens with a certain element, called as an allergen, which is commonly not reactive to ordinary individuals. Allergic diseases involve various organs or systems in the body. The purpose of allergy tests is to make a diagnosis of allergic diseases and to identify the affecting allergens. In vivo tests, more relevant in clinical situation, include skin test, patch test and provocation test. In in vitro tests, there are specific IgE test, histamine releasing assay, and lymphocyte activation test, safer and more objective than in vivo tests. In the view point of clinical practice, skin test, provocation test, total IgE test and specific IgE test were reviewed in depth.

Keywords

References

  1. Kim YL, Lee SK, Oh SH, Moon BS, Park HS, Hong CS. A study of allergy skin tests with Korean pollen extracts. Yonsei Med J 1987;28:112-8. https://doi.org/10.3349/ymj.1987.28.2.112
  2. Kang MG, Kim MY, Song WJ, Kim S, Jo EJ, Lee SE, et al. Patterns of inhalant allergen sensitization and geographical variation in Korean adults: A multicenter retrospective study. Allergy Asthma Immunol Res 2017;9:499-508. https://doi.org/10.4168/aair.2017.9.6.499
  3. Jeon Bh, Lee J, Kim JH, Kim JW, Lee HS, Lee KH. Atopy and sensitization rates to aeroallergens in children and teenagers in Jeju, Korea. Korean J Asthma Allergy Clin Immunol 2010;30:14-20.
  4. Lee HS, Hong SC, Kim SY, Lee KH, Kim JW, Kim JH, et al. The Influence of the residential environment on the sensitization rates to aeroallergens and the prevalence of allergic disorders in the school children in Jeju. Pediatr Allergy Respir Dis 2011;21:176-85. https://doi.org/10.7581/pard.2011.21.3.176
  5. Oh JW, Lee HB, Kang IJ, Kim SW, Park KS, Kook MH, et al. The revised edition of Korean calendar for allergenic pollens. Allergy Asthma Immunol Res 2012;4:5-11. https://doi.org/10.4168/aair.2012.4.1.5
  6. Hong YJ, Choi HY, Kim KJ, Lee GY, Kim DW, Kim SJ, et al. TRUE test in patients with contact dermatitis: A multicenter study. Korean J Dermatol 2011;49:661-9.
  7. Lee J, Sun HJ, Lee HY. Biohazard surveillance of allergic contact dermatitis in genetically-modified Zoysia grasses using patch testing. Allergy Asthma Respir Dis 2015;3:134-8. https://doi.org/10.4168/aard.2015.3.2.134
  8. Lee JH, Lee J. Is It Necessary to re-evaluate airway hyperresponsiveness during treatment of mild asthma? Korean J Med 2012;83:598-605. https://doi.org/10.3904/kjm.2012.83.5.598
  9. Hong CS, Park JW, Kim CW, Kang SM, Choi YH. Toluene diisocyanate inhalation bronchial challenge test with a closed-circuit device. Allergy 1995;15:598-610.
  10. Park HS, Cho YS, Park JN, Baik JH, Ruh NS, Cho DI, et al. Significant changes of bronchial responsiveness to methacholine after early asthmatic reaction to toluene diisocyanate (TDI) in a TDI-sensitive asthmatic worker. J Korean Med Sci 1990;5:185-8. https://doi.org/10.3346/jkms.1990.5.4.185
  11. Lee J, Lee TH, Kim YY, Yoo B, Moon HB, Cho YS. A Case of Anaphylaxis after drinking a beverage. Korean J Asthma Allergy Clin Immunol 2004;24:253-6.
  12. Lee J, Kim JW. Experience of Stevens-Johnson syndrome and toxic epidermal necrolysis in a regional hospital: 70 cases in 7 years. Korean J Med 2017;92:171-6. https://doi.org/10.3904/kjm.2017.92.2.171
  13. Oh EJ, Lee SA, Lim J, Park YJ, Han K, Kim Y. Detection of allergen specific IgE by AdvanSure allergy screen test. Korean J Lab Med 2010;30:420-31. https://doi.org/10.3343/kjlm.2010.30.4.420
  14. Kim HA, Ye YM, Hur GY, Kim SH, Suh CH, Nahm DH, et al. Comparative study of ImmunoCAP and ELISA for detecting allergen specific IgE to Japanese Hop pollen and two spotted spider mite. Korean J Asthma Allergy Clin Immunol 2006;26:129-35.
  15. Nam YH, Jeon DS, Lee SK. Comparison of skin prick test and serum specific IgE measured by ImmunoCAP system for various inhalant allergens. Allergy Asthma Respir Dis 2015;3:47-53. https://doi.org/10.4168/aard.2015.3.1.47