Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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Influences of the BUN and Creatinine Level by Krill (Euphausia superba) Meal and NaF Administration in Rats

Krill 분말 및 NaF 투여가 흰쥐의 BUN 및 Creatinine 농도에 미치는 영향

  • Kim, Han-Soo (Department of Food Science and Technology, Pusan National University)
  • Received : 2018.08.15
  • Accepted : 2018.09.20
  • Published : 2018.09.30
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Abstract

The aim of this study was to investigate the hematology and serum chemistry values on Sprague-Dawley rats, used krill (Euphausia superba) meal diet and sodium fluoride (NaF) for 5 weeks. Seven-week-old male rats were divided into five groups and fed experimental diets containing three krill meal contents, administrated orally 10 mg of NaF, basal diet group (BG), basal diet plus 10 mg of NaF group (BFG), 10.0% krill meal plus 10 mg of NaF group (KMF10), 20.0% krill meal plus 10 mg of NaF group (KMF20), and 30.0% krill meal plus 10 mg of NaF group (KMF30). Concentrations of non-esterified fatty acid (NEFA), blood urea nitrogen (BUN), creatinine in sera were significantly lower in the KMF10, KMF20, KMF30 than BFG (p<0.05). In uric acid concentration KMF10 showed no significant difference with the BFG group, was significantly lower than KMF20 and KMF30 (p<0.05). Total calcium (T-Ca) concentrations was all observed to be no significant difference, was increased with krill meal content (p<0.05). Phosphorus (Pi) concentration was no change in the content of krill meal. Accordingly, krill meal was considered to be effective in improving NEFA and BUN, creatinine, uric acid concentration.

Krill (Euphausia superba) 분말이 Sprague Dawley계 수컷 흰쥐 혈청 중 non-esterified fatty acid (NEFA), blood urea nitrogen (BUN), creatinine, uric acid 및 전해질 농도에 미치는 영향을 조사하기 위하여 기본식이를 급여한 대조군인 BG군과 기본식이에 NaF 10 mg 경구 투여한 BFG군을 비롯하여 10%, 20%, 30%의 krill 분말을 첨가한 식이에 NaF 10 mg 경구 투여한 KMF10군, KMF20군, KMF30군, 5가지의 급여군으로 나누어 5주간 사육한 결과, 흰쥐의 NEFA와 BUN, creatinine 농도는 krill 분말 급여군인 KMF10군, KMF20군, KMF30군에서 BFG군보다 유의적으로 감소한 결과가 관찰되었으며, uric acid 농도에서 KMF10군은 BFG군과 유의적 차이가 없었으나, KMF20군과 KMF30군에서 유의적으로 감소하였다(p<0.05). 또한 전해질 농도에서 총 칼슘(T-Ca)은 군간의 유의적 차이가 없는 것으로 관찰되었지만 krill 분말 함량에 따라 증가하였으며(p<0.05), 인(Pi) 농도는 krill meal 함량에 따른 변화는 없는 것으로 나타났다. 따라서, krill 분말은 NEFA 및 BUN, creatinine, uric acid 농도 개선에 효과가 있을 것으로 사료된다.

Keywords

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