생약학회지 (Korean Journal of Pharmacognosy)

  • 제49권3호
  • /
  • Pages.189-202
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  • 2018
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  • 0253-3073(pISSN)
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  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

홉의 주요 Phloroglucinol 및 Prenylated Flavonoid의 생물활성

Biological Activities of Phloroglucinols and Prenylated Flavonoids from Humuli Strobilus

  • Kim, Hyun Jung (College of Pharmacy and Natural Medicine Research Institute, Mokpo National University) ;
  • Yoon, Goo (College of Pharmacy and Natural Medicine Research Institute, Mokpo National University) ;
  • Cho, Young Chang (College of Pharmacy, Chonnam National University) ;
  • Lee, Ik-Soo (College of Pharmacy, Chonnam National University) ;
  • Kang, Bok Yun (College of Pharmacy, Chonnam National University)
  • 투고 : 2018.08.09
  • 심사 : 2018.09.12
  • 발행 : 2018.09.30
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초록

Hop cones (Humuli Strobili) are the female inflorescences of hop plants (Humulus lupulus L.) belonging to the family Cannabaceae. They have been used as herbal remedies to treat mood and sleep disturbances, and mainly to add as a bittering ingredient in brewing process. Considerable interests on pharmacological and biological activities of hop cones have been focused on their major constituents, namely, phloroglucinols (humulone, lupulone), terpenes (myrcene, humulene), and prenylated flavonoids (xanthohumol, isoxanthohumol, 6-prenylnaringenin, and 8-prenylnaringenin). The present review describes and discusses biological activity profiles of these major compounds in the hop cones.

키워드

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