대한화장품학회지 (Journal of the Society of Cosmetic Scientists of Korea)

  • 제44권3호
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  • Pages.295-302
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  • 2018
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  • 1226-2587(pISSN)
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  • 2288-9507(eISSN)
대한화장품학회 (Society of Cosmetic Scientists of Korea)
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접시꽃 캘러스 추출물의 천연화장품 원료로서의 효능 평가

Evaluation of Alcea rosea L. Callus Extract as a Natural Cosmetic Ingredient

  • 이기복 ((주)한국화장품제조 기술개발연구소) ;
  • 염아름 ((주)한국화장품제조 기술개발연구소) ;
  • 김동원 ((주)한국화장품제조 기술개발연구소) ;
  • 박창민 ((주)한국화장품제조 기술개발연구소) ;
  • 정민석 ((주)한국화장품제조 기술개발연구소) ;
  • 이기용 ((주)한국화장품제조 기술개발연구소) ;
  • 정철승 (충북 대학교)
  • Lee, Gibok (R&D Center, Hankook Cosmetics Manufacturing Co., Ltd.) ;
  • Yeom, Areum (R&D Center, Hankook Cosmetics Manufacturing Co., Ltd.) ;
  • Won, Kim Dong (R&D Center, Hankook Cosmetics Manufacturing Co., Ltd.) ;
  • Park, Chang-Min (R&D Center, Hankook Cosmetics Manufacturing Co., Ltd.) ;
  • Joung, Min-Seok (R&D Center, Hankook Cosmetics Manufacturing Co., Ltd.) ;
  • Lee, Gi Yong (R&D Center, Hankook Cosmetics Manufacturing Co., Ltd.) ;
  • Jeong, Cheol-seung (Chungbuk National University)
  • 투고 : 2018.07.09
  • 심사 : 2018.09.14
  • 발행 : 2018.09.30
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초록

본 연구에서는 천연 화장품 소재 개발을 위하여 접시꽃 캘러스 생리활성 효능에 대해서 평가하였다. 접시꽃캘러스 추출물의 항산화 효능은 DPPH, ABTS, FRAP assay를 통해서 확인하였다. 그 결과 접시꽃캘러스 추출물은 농도 의존적으로 강력한 항산화 능력을 확인되었다. 더불어, 접시꽃 캘러스 추출물은 10 mg/mL 의 농도에서 세포 내 ROS를 효과적으로 감소시키는 것으로 확인되었다. 접시꽃 캘러스 추출물의 미백효능을 평가하기 위해 tyrosinase 저해 효과를 확인한 결과, 접시꽃 캘러스 추출물은 10 mg/mL 의 농도에서 tyrosinase 활성을 51% 감소시키는 것으로 확인되었다. 이상의 결과를 바탕으로, 접시꽃 캘러스 추출물은 항산화 및 미백효능을 지닌 화장품 기능성 소재로서 적용 가치가 높은 천연소재로 사료된다.

In this study, we investigated the biological effects of Alcea rosea L. callus extract for the development of natural cosmetics ingredients. The antioxidant activities of A. rosea L. callus extract was measured through DPPH, ABTS and FRAP assay. As a result, A. rosea L. callus extract were found to have a strong antioxidant ability in a dose dependent manner. In addition, A. rosea L. callus effectively reduced the intracellular oxidative stress induced by AAPH at a concentration of 10 mg/mL. In a tyrosinase activity assay, we found that A. rosea L. callus extract reduced tyrosinase activity by 51% at 10 mg/mL. Based on these results, A. rosea L. callus extract is considered as a promising natural ingredients for cosmetics with antioxidant and whitening functions.

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