Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Beneficial Effect of Collagen-Peptide Mixture with GABA on Improvement Skin and Sleep Quality

콜라겐 펩타이드 및 GABA 복합물의 섭취가 피부 및 수면장애 개선에 미치는 영향

  • Kim, Jeong Kee (Vitalbeautie Research Institute, Amorepacific Corporation R&D center) ;
  • Lim, Seong Hwan (Vitalbeautie Research Institute, Amorepacific Corporation R&D center) ;
  • Kim, Wan Gi (Vitalbeautie Research Institute, Amorepacific Corporation R&D center) ;
  • Cho, Changhui (Skin Research Institute, IEC Korea) ;
  • Ha, Jaehyoun (Skin Research Institute, IEC Korea) ;
  • Seo, Dae Bang (Vitalbeautie Research Institute, Amorepacific Corporation R&D center)
  • 김정기 (바이탈뷰티연구소, 아모레퍼시픽 기술연구원) ;
  • 임성환 (바이탈뷰티연구소, 아모레퍼시픽 기술연구원) ;
  • 김완기 (바이탈뷰티연구소, 아모레퍼시픽 기술연구원) ;
  • 조창희 (임상연구소, IEC Korea) ;
  • 하재현 (임상연구소, IEC Korea) ;
  • 서대방 (바이탈뷰티연구소, 아모레퍼시픽 기술연구원)
  • Received : 2018.06.26
  • Accepted : 2018.09.06
  • Published : 2018.09.30
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Abstract

Collagen peptide plays a protective role in skin by increasing the activity of antioxidant, acts like an activator of skin regeneration by positive feedback and is used as a potent candidate for cosmetics or functional food. GABA acts at inhibitory synapses in the brain by binding to specific transmembrane receptors of both pre- and postsynaptic neuronal processes in vertebrates, is also involved in the synthesis of melatonin and might exert regulatory effects on sleep and reproductive functions. In this study, we investigated the beneficial effect of a mixture of collagen peptide and GABA (J85091900) on skin and sleep condition in woman experiencing sleep disorder. We found that oral supplement with J85091900 significantly decreased the value of Pittsburgh Sleep Quality Index (PSQI), increased sleeping time by 7%, and also improved skin roughness (Ra, Rz, Rt), periorbital wrinkle (Ra, Rt), and skin capacitance in human. These findings indicate that dual strategy with which skin improvement is accomplished using collagen peptide and sleeping well is acquired using GABA could be the novel solution for sleeping beauty by edible cosmetics to improve skin status.

콜라겐 펩타이드(collagen peptide)는 단백질의 가수 분해물로서 주름 완화, 보습력 증대, 탄력 개선 등의 특정 피부 효능을 나타낼 수 있어 화장품 혹은 피부 개선 기능식품으로서 활용되고 있다. ${\gamma}-aminobutyric$ acid (GABA)는 척추 동물의 뇌, 척수에 존재하는 신경전달 물질로서 수면의 질과 양을 개선해 준다고 알려져 있다. 본 연구에서는 콜라겐 펩타이드와 GABA의 복합물이 수면 장애가 있는 여성에게 8주 경구 섭취를 통해서 수면 및 피부 상태를 개선할 수 있는가에 관하여 확인하였다. 복합물(J85091900)은 8주간 연속적으로 섭취 시, 수면장애지수(PSQI)가 유의적으로 감소하였으며, 수면 시간을 7% 증가시켰다. 또한, 피부 거칠기, 눈가 주름 및 피부 수분량(capacitance)을 유의적으로 개선하였다. 이상의 결과에서 콜라겐과 GABA의 복합물은 복합 수면 장애에 따른 피부의 노화 현상으로부터 피부를 보호할 수 있음을 확인하여 먹는 화장품의 핵심 소재로 활용 가능함을 확인하였다.

Keywords

References

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