대한수의학회지 (Korean Journal of Veterinary Research)

  • 제58권3호
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  • Pages.143-146
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  • 2018
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  • 2466-1384(pISSN)
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  • 2466-1392(eISSN)
대한수의학회 (The Korean Society of Veterinary Science)
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Genetic variations in open reading frame 2 gene of porcine circovirus type 2 isolated in Korea during 2016-2017

  • Kim, Kiju (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Choi, Jong-Young (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Lyoo, Kwang-Soo (Korea Zoonosis Research Institute, Chonbuk National University) ;
  • Hahn, Tae-Wook (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University)
  • 투고 : 2018.06.21
  • 심사 : 2018.07.18
  • 발행 : 2018.09.30
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초록

The capsid protein of porcine circovirus type 2 (PCV2) encoded by open reading frame 2 (ORF2) is important for neutralizing activity against PCV2 infection. This study investigated the heterogeneity of the ORF2 gene of PCV2 isolated in Korea during 2016-2017. The results revealed that PCV2d is currently the predominant genotype. Moreover, comparison of ORF2 from 17 PCV2 isolates revealed 88.3-100% homology at the nucleotide (deduced amino acid 86.3-100%) level. Interestingly, 61.5% (8/13) of the PCV2d isolates had glycine at position 210. These data provide a useful information for PCV2 epidemiology in Korea.

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참고문헌

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