DOI QR코드

DOI QR Code

GEANT4-based Monte Carlo Simulation of Beam Quality Correction Factors for the Leksell Gamma Knife® PerfexionTM

  • Schaarschmidt, Thomas (Department of Nuclear Engineering, Hanyang University) ;
  • Kim, Tae Hoon (Department of Nuclear Engineering, Hanyang University) ;
  • Kim, Yong Kyun (Department of Nuclear Engineering, Hanyang University) ;
  • Yang, Hye Jeong (Department of Biomedicine & Health Sciences and Biomedical Engineering, Catholic University College of Medicine) ;
  • Chung, Hyun-Tai (Department of Neurosurgery, Seoul National University College of Medicine)
  • Received : 2018.09.19
  • Accepted : 2018.11.09
  • Published : 2018.12.30

Abstract

With the publication of TRS-483 in late 2017 the IAEA has established an international code of practice for reference dosimetry in small and non-standard fields based on a formalism first suggested by Alfonso et al. in 2008. However, data on beam quality correction factors ($k^{f_{msr},f_{ref}}_{Q_{msr},Q_0}$) for the Leksell Gamma $Knife^{(R)}$ $Perfexion^{TM}$ is scarce and what little data is available was obtained under conditions not necessarily in accordance with the IAEA's recommendations. This study constitutes the first systematic attempt to calculate those correction factors by applying the new code of practice to Monte Carlo simulation using the GEANT4 toolkit. $k^{f_{msr},f_{ref}}_{Q_{msr},Q_0}$ values were determined for three common ionization chamber detectors and five different phantom materials, with results indicating that in most phantom materials, all chambers were well suited for reference dosimetry with the Gamma $Knife^{(R)}$. Similarities and differences between the results of this study and previous ones were also analyzed and it was found that the results obtained herein were generally in good agreement with earlier PENELOPE and EGSnrc studies.

Keywords

Acknowledgement

Supported by : Korea Agency for Technology and Standards

References

  1. International Atomic Energy Agency, Absorbed dose determination in external beam radiotherapy: an international code of practice for dosimetry based on standards of absorbed dose to water, Technical Report Series No. 398, Vienna (2000).
  2. P. R. Almond et al., Med. Phys. 26, 1847 (1999). https://doi.org/10.1118/1.598691
  3. Institute of Physics and Engineering in Medicine, Small eld MV photon dosimetry, IPEM Report No. 103, York (2010).
  4. R. Alfonso et al., Med. Phys. 35, 5179 (2008). https://doi.org/10.1118/1.3005481
  5. International Atomic Energy Agency, Dosimetry of small static fields used in external beam radiotherapy: an IAEA-AAPM international code of practice for reference and relative dose determination, Technical Report Series No. 483, Vienna (2017).
  6. J. Johansson et al., Presentation at the 16th International Meeting of the Leksell Gamma Knifer$^{(R)}$ Society, Sydney (2012).
  7. E. Zoros et al., Phys. Med. Biol. 62, 7532 (2017). https://doi.org/10.1088/1361-6560/aa8590
  8. L. Mirzakhanian, H. Benmakhlouf, F. Tessier and J. Seutjens, Med. Phys. 45, 1748 (2018). https://doi.org/10.1002/mp.12821
  9. C. Lindquist and I. Paddick, Operative Neurosurgery 61, ONS-131 (2007).
  10. C. M. Poole et al., IEEE Trans. Nucl. Sci. 59, 1695 (2012). https://doi.org/10.1109/TNS.2012.2197415
  11. T. H. Kim et al., Development of IAEA phase-space database for Leksell Gamma Knifer$^{(R)}$ $Perfexion^{TM}$ using multi-threaded GEANT4 simulation, Phys. Med. Biol. (2018) (under review).
  12. EStar material composition database of the US National Institute of Standards and Technology, https://physics.nist.gov/cgi-bin/Star/compos.pl.
  13. F. Araki, Physica Medica 39, 132 (2017). https://doi.org/10.1016/j.ejmp.2017.06.011
  14. J. Novotny Jr. et al., Med. Phys. 37, 5066 (2010). https://doi.org/10.1118/1.3481508
  15. Homepage of the GEANT4 simulation toolkit at CERN, https://geant4.web.cern.ch/.
  16. S. Incerti, M. Asai and D. Wright, GEANT4 Tutorial at KIRAMS, Seoul, Korea, (2017) (http://geant4.in2p3.fr/IMG/pdf PhysicsLists.pdf).
  17. British Institute of Radiology, Central Axis Depth Dose Data for Use in Radiotherapy, British Journal of Radiology Supplement 25, London (1996).
  18. J. Allison et al., Nucl. Instrum. Meth. Phys. Res. A 835, 186 (2015).
  19. G. M. Mora, A. Maio and D. W. Rogers, Med. Phys. 26, 2494 (1999). https://doi.org/10.1118/1.598770

Cited by

  1. Feasibility Study of a Small Field Detector Based on a Microfluidic Calorimeter vol.74, pp.7, 2019, https://doi.org/10.3938/jkps.74.630
  2. Evaluation and validation of the convolution algorithm for Leksell Gamma knife radiosurgery vol.65, pp.15, 2018, https://doi.org/10.1088/1361-6560/ab91da
  3. Experimental investigation of TRS‐483 reference dosimetry correction factors for Leksell Gamma Knife® Icon™ beams vol.48, pp.1, 2018, https://doi.org/10.1002/mp.14561