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Real-Time Localization of Parathyroid Glands with Near Infrared Light during Thyroid and Parathyroid Surgery

갑상선·부갑상선 수술 중 근적외선을 이용한 실시간 부갑상선의 국소화

  • Kim, Sung Won (Department of Otolaryngology-Head and Neck Surgery, Kosin University College of Medicine) ;
  • Jeong, Yeong Wook (Department of Otolaryngology-Head and Neck Surgery, Kosin University College of Medicine) ;
  • Koh, Yoon Woo (Department of Otorhinolaryngology-Head and Neck Surgery, Yonsei University College of Medicine) ;
  • Lee, Kang Dae (Department of Otolaryngology-Head and Neck Surgery, Kosin University College of Medicine)
  • 김성원 (고신대학교 의과대학 이비인후과학교실) ;
  • 정영욱 (고신대학교 의과대학 이비인후과학교실) ;
  • 고윤우 (연세대학교 의과대학 이비인후과학교실) ;
  • 이강대 (고신대학교 의과대학 이비인후과학교실)
  • Received : 2018.08.09
  • Accepted : 2018.10.23
  • Published : 2018.11.30

Abstract

Intraoperative identification and localization of parathyroid glands are crucial step in preventing postoperative hypocalcemia during thyroid and parathyroid surgery. If there is a method to predict the parathyroid's location rather than detecting and verifying with naked eye, it would make the operator easier to find and identify the parathyroid. Recently, near-infrared light imaging technologies have been introduced in the fields of thyroid and parathyroid surgery to predict the localization of the parathyroid. These are being conducted in two ways: autofluorescence imaging with a unique intrinsic fluorophore in the parathyroid tissues and fluorescence imaging with external fluorescence materials specially absorbed into parathyroid tissues. We are suggest that parathyroid glands can be detected by surgeon with NIR autofluorescence imaging even if they are covered by fibrofatty tissues before they are detected by surgeon's naked eye. These novel techniques are very useful to identify and preserve parathyroid glands during thyroidectomy. In this article, we reviewed the latest papers that describe autofluorescence imaging and exogenous ICG fluorescence imaging of parathyroid glands during thyroid and parathyroid surgery.

Keywords

Acknowledgement

Supported by : Hanmi Pharmacutical

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