Textile Science and Engineering (한국섬유공학회지)

The Korean Fiber Society (한국섬유공학회)
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Physical and Biological Properties of Bio-membranes Obtained by Using PVA and Sulfonated Polymers

PVA와 술폰화된 생체고분자를 이용한 생체막의 물리적 생물학적 특성

  • Kim, Min Gu (Department of Physical Therapy, Eulji University) ;
  • Lee, Dong Keon (Department of Advanced Materials and Chemical Engineering, Hannam University) ;
  • Kwon, Hyuck Joon (Department of Physical Therapy, Eulji University) ;
  • Na, Yang Ho (Department of Advanced Materials and Chemical Engineering, Hannam University)
  • 김민구 (을지대학교 물리치료학과) ;
  • 이동건 (한남대학교 화공신소재공학과) ;
  • 권혁준 (을지대학교 물리치료학과) ;
  • 나양호 (한남대학교 화공신소재공학과)
  • Received : 2018.07.17
  • Accepted : 2018.08.20
  • Published : 2018.08.31
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Abstract

We prepared bio-membranes by mixing polyvinyl alcohol (PVA) with a natural polymer [${\kappa}$-Carrageenan (${\kappa}-Car$) or chondroitin sulfate (CS)] having a sulfonate group similar to proteoglycan of articular cartilage and investigated the mechanical, thermal, and surface properties of these bio-membranes that varied with the content ratio of the natural polymer. We found that the mechanical properties of the bio-membranes decreased with the ratio of ${\kappa}-Car$ or CS. It was found that the mesenchymal stem cells (MSCs) virtually did not adhere to the PVA hydrogel film prepared by freeze-thawing method, whereas they adhered to the PVA hydrogel film prepared by solution casting. In addition, the adhesion rate of the MSCs on the bio-membranes gradually increased with the ratio of ${\kappa}-Car$ or CS.

Keywords

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