Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Current Status of Microbial Phenylethanoid Biosynthesis

  • Kim, Song-Yi (Department of Integrative Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University) ;
  • Song, Min Kyung (Department of Integrative Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University) ;
  • Jeon, Ju Hyun (Department of Integrative Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University) ;
  • Ahn, Joong-Hoon (Department of Integrative Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University)
  • Received : 2018.05.14
  • Accepted : 2018.05.30
  • Published : 2018.08.28
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Abstract

Phenylethanoids, including 2-phenylethanol, tyrosol, and salidroside are a group of phenolic compounds with a C6-C2 carbon skeleton synthesized by plants. Phenylethanoids display a variety of biological activities, including antibacterial, anticancer, anti-inflammatory, neuroprotective, and anti-asthmatic activities. Recently, successful microbial synthesis of phenylethanoids through metabolic engineering and synthetic biology approaches has been reported and could allow phenylethanoid production from alternative microbial sources. Here, we review the recent achievements in the synthesis of phenylethanoids by microorganisms. The work done so far will contribute to the production of diverse phenylethanoids using various microbial systems and facilitate exploration of further diverse biological activities of phenylethanoids.

Keywords

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