DOI QR코드

DOI QR Code

Retention of BioAggregate and MTA as coronal plugs after intracanal medication for regenerative endodontic procedures: an ex vivo study

  • 투고 : 2017.10.31
  • 심사 : 2018.03.04
  • 발행 : 2018.08.31

초록

Objectives: This study compared the retention of BioAggregate (BA; Innovative BioCeramix) and mineral trioxide aggregate (MTA; Angelus) as coronal plugs after applying different intracanal medications (ICMs) used in regenerative endodontic. Materials and Methods: One-hundred human maxillary central incisors were used. The canals were enlarged to a diameter of 1.7 mm. Specimens were divided into 5 groups (n = 20) according to the ICM used: calcium hydroxide (CH), 2% chlorhexidine (CHX), triple-antibiotic paste (TAP), double-antibiotic paste (DAP), and no ICM (control; CON). After 3 weeks of application, ICMs were removed and BA or MTA were placed as the plug material (n = 10). The push-out bond strength and the mode of failure were assessed. The data were analyzed using 2-way analysis of variance, the Tukey's test, and the ${\chi}^2$ test; p values < 0.05 indicated statistical significance. Results: The type of ICM and the type of plug material significantly affected bond strength (p < 0.01). Regardless of the type of ICM, BA showed a lower bond strength than MTA (p < 0.05). For MTA, CH showed a higher bond strength than CON, TAP and DAP; CHX showed a higher bond strength than DAP (p < 0.01). For BA, CH showed a higher bond strength than DAP (p < 0.05). The mode of failure was predominantly cohesive for BA (p < 0.05). Conclusions: MTA may show better retention than BA. The mode of bond failure with BA can be predominantly cohesive. BA retention may be less affected by ICM type than MTA retention.

키워드

참고문헌

  1. Galler KM. Clinical procedures for revitalization: current knowledge and considerations. Int Endod J 2016;49:926-936. https://doi.org/10.1111/iej.12606
  2. Kontakiotis EG, Filippatos CG, Tzanetakis GN, Agrafioti A. Regenerative endodontic therapy: a data analysis of clinical protocols. J Endod 2015;41:146-154.
  3. Kahler B, Rossi-Fedele G. A review of tooth discoloration after regenerative endodontic therapy. J Endod 2016;42:563-569. https://doi.org/10.1016/j.joen.2015.12.022
  4. Tagelsir A, Yassen GH, Gomez GF, Gregory RL. Effect of antimicrobials used in regenerative endodontic procedures on 3-week-old Enterococcus faecalis biofilm. J Endod 2016;42:258-262. https://doi.org/10.1016/j.joen.2015.09.023
  5. Prabhakar A, Taur S, Hadakar S, Sugandhan S. Comparison of antibacterial efficacy of calcium hydroxide paste, 2% chlorhexidine gel and turmeric extract as an intracanal medicament and their effect on microhardness of root dentin: an in vitro study. Int J Clin Pediatr Dent 2013;6:171-177.
  6. Abu Zeid ST, Khafagi MG, Abou Neel EA. Effect of root canal medications on maturation and calcification of root canal dentin' hydroxyapatite. Spectrosc Lett 2016;49:135-139. https://doi.org/10.1080/00387010.2015.1099109
  7. Camilleri J, Grech L, Galea K, Keir D, Fenech M, Formosa L, Damidot D, Mallia B. Porosity and root dentine to material interface assessment of calcium silicate-based root-end filling materials. Clin Oral Investig 2014;18:1437-1446. https://doi.org/10.1007/s00784-013-1124-y
  8. Camilleri J, Sorrentino F, Damidot D. Characterization of un-hydrated and hydrated BioAggregate and MTA Angelus. Clin Oral Investig 2015;19:689-698. https://doi.org/10.1007/s00784-014-1292-4
  9. Zhang H, Pappen FG, Haapasalo M. Dentin enhances the antibacterial effect of mineral trioxide aggregate and bioaggregate. J Endod 2009;35:221-224. https://doi.org/10.1016/j.joen.2008.11.001
  10. Hashem AA, Wanees Amin SA. The effect of acidity on dislodgment resistance of mineral trioxide aggregate and bioaggregate in furcation perforations: an in vitro comparative study. J Endod 2012;38:245-249. https://doi.org/10.1016/j.joen.2011.09.013
  11. Huan Z, Chang J. Novel tricalcium silicate/monocalcium phosphate monohydrate composite bone cement. J Biomed Mater Res B Appl Biomater 2007;82:352-359.
  12. Schembri-Wismayer P, Camilleri J. Why biphasic? Assessment of the effect on cell proliferation and expression. J Endod 2017;43:751-759. https://doi.org/10.1016/j.joen.2016.12.022
  13. Tian J, Zhang Y, Lai Z, Li M, Huang Y, Jiang H, Wei X. Ion release, microstructural, and biological properties of iRoot BP Plus and ProRoot MTA exposed to an acidic environment. J Endod 2017;43:163-168. https://doi.org/10.1016/j.joen.2016.10.011
  14. Guven Y, Tuna EB, Dincol ME, Ozel E, Yilmaz B, Aktoren O. Long-term fracture resistance of simulated immature teeth filled with various calcium silicate-based materials. Biomed Res Int 2016;2016:2863817.
  15. Keskin C, Demiryurek EO, Ozyurek T. Color stabilities of calcium silicate-based materials in contact with different irrigation solutions. J Endod 2015;41:409-411. https://doi.org/10.1016/j.joen.2014.11.013
  16. Tuloglu N, Bayrak S. Comparative evaluation of mineral trioxide aggregate and bioaggregate as apical barrier material in traumatized nonvital, immature teeth: a clinical pilot study. Niger J Clin Pract 2016;19:52-57. https://doi.org/10.4103/1119-3077.164332
  17. Topcuoglu HS, Arslan H, Akcay M, Saygili G, Cakici F, Topcuoglu G. The effect of medicaments used in endodontic regeneration technique on the dislocation resistance of mineral trioxide aggregate to root canal dentin. J Endod 2014;40:2041-2044. https://doi.org/10.1016/j.joen.2014.08.018
  18. Turk T, Fidler A. Effect of medicaments used in endodontic regeneration technique on push-out bond strength of MTA and Biodentine. Biotechnol Biotechnol Equip 2016;30:140-144. https://doi.org/10.1080/13102818.2015.1109477
  19. Turk T, Ozisik B, Aydin B. Time-dependent effectiveness of the intracanal medicaments used for pulp revascularization on the dislocation resistance of MTA. BMC Oral Health 2015;15:130-135. https://doi.org/10.1186/s12903-015-0117-4
  20. Nagas E, Cehreli ZC, Uyanik MO, Vallittu PK, Lassila LV. Effect of several intracanal medicaments on the push-out bond strength of ProRoot MTA and Biodentine. Int Endod J 2016;49:184-188. https://doi.org/10.1111/iej.12433
  21. Saghiri MA, Garcia-Godoy F, Gutmann JL, Lotfi M, Asatourian A, Ahmadi H. Push-out bond strength of a nano-modified mineral trioxide aggregate. Dent Traumatol 2013;29:323-327. https://doi.org/10.1111/j.1600-9657.2012.01176.x
  22. Saghiri MA, Asatourian A, Garcia-Godoy F, Gutmann JL, Sheibani N. The impact of thermocycling process on the dislodgement force of different endodontic cements. Biomed Res Int 2013;2013:317185.
  23. Majeed A, AlShwaimi E. Push-out bond strength and surface microhardness of calcium silicate-based biomaterials: an in vitro study. Med Princ Pract 2017;26:139-145. https://doi.org/10.1159/000453455
  24. Shokouhinejad N, Razmi H, Nekoofar MH, Sajadi S, Dummer PM, Khoshkhounejad M. Push-out bond strength of bioceramic materials in a synthetic tissue fluid. J Dent (Tehran) 2013;10:540-547.
  25. Chedella SC, Berzins DW. A differential scanning calorimetry study of the setting reaction of MTA. Int Endod J 2010;43:509-518. https://doi.org/10.1111/j.1365-2591.2010.01708.x
  26. Amin SA, Seyam RS, El-Samman MA. The effect of prior calcium hydroxide intracanal placement on the bond strength of two calcium silicate-based and an epoxy resin-based endodontic sealer. J Endod 2012;38:696-699. https://doi.org/10.1016/j.joen.2012.02.007
  27. Grattan-Bellew PE. Microstructural investigation of deteriorated Portland cement concretes. Constr Build Mater 1996;10:3-16. https://doi.org/10.1016/0950-0618(95)00066-6
  28. Shokouhinejad N, Nekoofar MH, Iravani A, Kharrazifard MJ, Dummer PM. Effect of acidic environment on the push-out bond strength of mineral trioxide aggregate. J Endod 2010;36:871-874. https://doi.org/10.1016/j.joen.2009.12.025
  29. Shokouhinejad N, Yazdi KA, Nekoofar MH, Matmir S, Khoshkhounejad M. Effect of acidic environment on dislocation resistance of Endosequence root repair material and mineral trioxide aggregate. J Dent (Tehran) 2014;11:161-166.
  30. Shokouhinejad N, Nekoofar MH, Razmi H, Sajadi S, Davies TE, Saghiri MA, Gorjestani H, Dummer PM. Bioactivity of EndoSequence root repair material and bioaggregate. Int Endod J 2012;45:1127-1134. https://doi.org/10.1111/j.1365-2591.2012.02083.x
  31. Sideris K, Manita P. Estimation of ultimate modulus of elasticity and Poisson ratio of normal concrete. Cem Concr Compos 2004;26:623-631. https://doi.org/10.1016/S0958-9465(03)00084-2
  32. Twati WA, Wood DJ, Liskiewicz TW, Willmott NS, Duggal MS. An evaluation of the effect of non-setting calcium hydroxide on human dentine: a pilot study. Eur Arch Paediatr Dent 2009;10:104-109. https://doi.org/10.1007/BF03321610
  33. Chen WP, Chen YY, Huang SH, Lin CP. Limitations of push-out test in bond strength measurement. J Endod 2013;39:283-287. https://doi.org/10.1016/j.joen.2012.11.002
  34. Pane ES, Palamara JE, Messer HH. Critical evaluation of the push-out test for root canal filling materials. J Endod 2013;39:669-673. https://doi.org/10.1016/j.joen.2012.12.032
  35. Saghiri MA, Garcia-Godoy F, Asatourian A, Lotfi M, Banava S, Khezri-Boukani K. Effect of pH on compressive strength of some modification of mineral trioxide aggregate. Med Oral Patol Oral Cir Bucal 2013;18:e714-e720.
  36. Bolhari B, Nekoofar MH, Sharifian M, Ghabrai S, Meraji N, Dummer PM. Acid and microhardness of mineral trioxide aggregate and mineral trioxide aggregate-like materials. J Endod 2014;40:432-435. https://doi.org/10.1016/j.joen.2013.10.014
  37. Jang YE, Lee BN, Koh JT, Park YJ, Joo NE, Chang HS, Hwang IN, Oh WM, Hwang YC. Cytotoxicity and physical properties of tricalcium silicate-based endodontic materials. Restor Dent Endod 2014;39:89-94. https://doi.org/10.5395/rde.2014.39.2.89
  38. Shie MY, Huang TH, Kao CT, Huang CH, Ding SJ. The effect of a physiologic solution pH on properties of white mineral trioxide aggregate. J Endod 2009;35:98-101.
  39. Yassen GH, Vail MM, Chu TG, Platt JA. The effect of medicaments used in endodontic regeneration on root fracture and microhardness of radicular dentine. Int Endod J 2013;46:688-695. https://doi.org/10.1111/iej.12046
  40. Berkhoff JA, Chen PB, Teixeira FB, Diogenes A. Evaluation of triple antibiotic paste removal by different irrigation procedures. J Endod 2014;40:1172-1177. https://doi.org/10.1016/j.joen.2013.12.027
  41. Yassen GH, Chu TM, Eckert G, Platt JA. Effect of medicaments used in endodontic regeneration technique on the chemical structure of human immature radicular dentin: an in vitro study. J Endod 2013;39:269-273. https://doi.org/10.1016/j.joen.2012.09.020
  42. Yassen GH, Chu TM, Gallant MA, Allen MR, Vail MM, Murray PE, Platt JA. A novel approach to evaluate the effect of medicaments used in endodontic regeneration on root canal surface indentation. Clin Oral Investig 2014;18:1569-1575. https://doi.org/10.1007/s00784-013-1125-x
  43. Prather BT, Ehrlich Y, Spolnik K, Platt JA, Yassen GH. Effects of two combinations of triple antibiotic paste used in endodontic regeneration on root microhardness and chemical structure of radicular dentine. J Oral Sci 2014;56:245-251. https://doi.org/10.2334/josnusd.56.245
  44. Yassen GH, Eckert GJ, Platt JA. Effect of intracanal medicaments used in endodontic regeneration procedures on microhardness and chemical structure of dentin. Restor Dent Endod 2015;40:104-112. https://doi.org/10.5395/rde.2015.40.2.104
  45. Yilmaz S, Dumani A, Yoldas O. The effect of antibiotic pastes on microhardness of dentin. Dent Traumatol 2016;32:27-31. https://doi.org/10.1111/edt.12193
  46. Yassen GH, Platt JA. The effect of nonsetting calcium hydroxide on root fracture and mechanical properties of radicular dentine: a systematic review. Int Endod J 2013;46:112-118. https://doi.org/10.1111/j.1365-2591.2012.02121.x
  47. Shetty S, Manjunath MK, Tejaswi S. An in-vitro evaluation of the pH change through root dentin using different calcium hydroxide preparations as an intracanal medicament. J Clin Diagn Res 2014;8:ZC13-ZC16.
  48. Saghiri MA, Shokouhinejad N, Lotfi M, Aminsobhani M, Saghiri AM. Push-out bond strength of mineral trioxide aggregate in the presence of alkaline pH. J Endod 2010;36:1856-1859. https://doi.org/10.1016/j.joen.2010.08.022
  49. Arslan H, Akcay M, Capar ID, Ertas H, Ok E, Uysal B. Efficacy of needle irrigation, EndoActivator, and photon-initiated photoacoustic streaming technique on removal of double and triple antibiotic pastes. J Endod 2014;40:1439-1442. https://doi.org/10.1016/j.joen.2014.02.013
  50. Mohammadi Z, Abbott PV. On the local applications of antibiotics and antibiotic-based agents in endodontics and dental traumatology. Int Endod J 2009;42:555-567. https://doi.org/10.1111/j.1365-2591.2009.01564.x
  51. Tjaderhane L, Nascimento FD, Breschi L, Mazzoni A, Tersariol IL, Geraldeli S, Tezvergil-Mutluay A, Carrilho M, Carvalho RM, Tay FR, Pashley DH. Strategies to prevent hydrolytic degradation of the hybrid layer: a review. Dent Mater 2013;29:999-1011. https://doi.org/10.1016/j.dental.2013.07.016
  52. Sabatini C, Pashley DH. Mechanisms regulating the degradation of dentin matrices by endogenous dentin proteases and their role in dental adhesion. A review. Am J Dent 2014;27:203-214.
  53. Ari H, Erdemir A, Belli S. Evaluation of the effect of endodontic irrigation solutions on the microhardness and the roughness of root canal dentin. J Endod 2004;30:792-795. https://doi.org/10.1097/01.DON.0000128747.89857.59

피인용 문헌

  1. Regenerative Endodontic Procedures, Disinfectants and Outcomes: A Systematic Review vol.9, pp.4, 2018, https://doi.org/10.1177/2050168420963302