Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Reference Values of Whole Blood Viscosity and Its Correlation with Hematology and Serum Chemistry in Beagle Dogs

  • Koh, Jun (BK 21 Plus Program and College of Veterinary Medicine, Chonbuk National University) ;
  • Lee, Dong-bin (College of Veterinary Medicine, Western University of Health Sciences) ;
  • Lee, Dong Han (College of Engineering, Chonbuk National University) ;
  • Kim, Nam Soo (BK 21 Plus Program and College of Veterinary Medicine, Chonbuk National University)
  • Received : 2017.09.20
  • Accepted : 2017.12.20
  • Published : 2018.06.30
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Abstract

The aim of this study was to measure whole blood viscosity (WBV) and then to establish its reference values and identify correlation between WBV and hematology or serum chemistry in beagle. The experiment was made up of 82 healthy beagle dogs. Jugular vein blood samples (10 ml) were collected. WBV (cP) measured within 4 hours after collection by U-shaped scanning capillary-tube viscometer ($BVD-PRO1^{(R)}$) which is capable of measuring yield stress and viscosity of whole blood continuously over a wide range of shear rates from $1s^{-1}$ to $1000s^{-1}$ is new type of capillary tube viscometer and calculates viscosity using Casson fluid model. Measured values of WBV, Complete blood cell count, serum chemistry were analyzed by RM-ANOVA test. Mean diastolic and systolic WBV (cP) were $29.032{\pm}6.137$ and $4.528{\pm}0.865$. Bodyweight (BW), Red blood cell count (RBC), Hemoglobin (HGB), Hematocrit (HCT), Alkaline phosphatase (ALP), Cholestetol (CHOL), Total protein (TP), Globulin, Chloride (Cl), Fibrinogen, were statistically correlated with WBV over whole range of shear rates (p < 0.05). This study newly evaluated reference values of WBV by U-shaped viscometer in beagle. Correlation between WBV and BW, RBC, HGB, HCT, ALP, CHOL, TP, Globulin, Cl, Fibrinogen was presented.

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References

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