대한지역사회작업치료학회지 (The Journal of Korean society of community based occupational therapy)

대한지역사회작업치료학회 (Korean Society of Community Based Occupational Therapy Association)
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복합운동프로그램이 수면장애 모델 쥐의 뇌기능과 수면장애에 미치는 영향

The Effect of Combined Exercise on Brain Function and Sleep Disorder of Sleep Disturbance Rats

  • 김동현 (김천대학교 작업치료학과)
  • 투고 : 2018.11.30
  • 심사 : 2018.12.24
  • 발행 : 2018.12.31
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⟨ 이전 논문 다음 논문 ⟩

초록

목적 : 본 연구는 복합운동프로그램이 수면장애 모델 쥐의 수면장애 개선과 뇌기능 기억력에 어떠한 영향을 주는지 신경생리학적 접근을 통한 과학적 근거를 제시하는데 그 목적이 있다. 연구방법 : 본 연구는 수면장애 모델 쥐 16마리에게 동물실험실에서 제작된 복합운동프로그램을 적용하여 4일간 실시하였다. 실시 후 뇌기능은 해마의 BDNF의 변화를 확인하였고 수면의 변화는 혈액 중의 멜라토닌의 농도를 확인하였다. 결과 : 첫째, 복합운동프로그램의 뇌기능에 대한 영향은 실험군에서 유의미한 증가를 보였다(p<0.01). 둘째, 복합운동프로그램의 수면장애에 대한 영향은 실험군과 대조군에서 유의미한 증가를 보였다(p<0.01) (p<0.05). 결론 : 지역사회의 노인증가율이 급속히 증가하고 있으며 노인의 수면장애는 이러한 노인들의 삶의 질에 영향을 줄 수 있다. 그리고 수면장애로 인한 이차적인 기억력 저하도 문제가 될 수 있다. 수면장애를 개선할 수 있는 방법은 여러 가지가 있겠지만 경제적, 공간적으로 부담이 되지 않는 복합운동만으로도 수면과 기억의 개선을 도모할 수 있음을 실험동물을 통하여 과학적으로 증명하였다.

Objective : The study was to investigate the neurophysiological approach to the effect of complex exercise on memory, one of brain functions, and the degree of sleep disorder using experimental animals with sleep disorders. Methods : This study carried out a complex exercise that designed in an animal laboratory for 4 days to 16 sleep - disordered model rats. After the exercise, brain function was confirmed with the changes of BDNF in the hippocampus and the change of sleep level was confirmed with the concentration of melatonin in the blood. Results : First, the effect of the complex exercise program on brain function was significantly increased in the experimental group(p<0.01). Second, the effect of complex exercise program on sleep disturbance was significantly increased in the experimental group and control group(p<0.01)(p<0.05). Conclusion : The rate of increase of the elderly in the community is rapidly increasing, and the sleep disorder of the elderly can affect the quality of life of these elderly people. Secondary memory impairment due to sleep disturbances can also be a problem. Although there are many ways to improve sleep disturbance, it has been scientifically proven through experimental animals that sleep and memory can be improved with complex exercise that is not economically, spatially burdensome.

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