DOI QR코드

DOI QR Code

Skin Lesion Image Segmentation Based on Adversarial Networks

  • Wang, Ning (College of Information Science and Engineering, Shandong University of Science and Technology) ;
  • Peng, Yanjun (College of Information Science and Engineering, Shandong University of Science and Technology) ;
  • Wang, Yuanhong (College of Information Science and Engineering, Shandong University of Science and Technology) ;
  • Wang, Meiling (College of Information Science and Engineering, Shandong University of Science and Technology)
  • Received : 2017.09.18
  • Accepted : 2018.01.18
  • Published : 2018.06.30

Abstract

Traditional methods based active contours or region merging are powerless in processing images with blurring border or hair occlusion. In this paper, a structure based convolutional neural networks is proposed to solve segmentation of skin lesion image. The structure mainly consists of two networks which are segmentation net and discrimination net. The segmentation net is designed based U-net that used to generate the mask of lesion, while the discrimination net is designed with only convolutional layers that used to determine whether input image is from ground truth labels or generated images. Images were obtained from "Skin Lesion Analysis Toward Melanoma Detection" challenge which was hosted by ISBI 2016 conference. We achieved segmentation average accuracy of 0.97, dice coefficient of 0.94 and Jaccard index of 0.89 which outperform the other existed state-of-the-art segmentation networks, including winner of ISBI 2016 challenge for skin melanoma segmentation.

Keywords

References

  1. R. J. Mermelstein and L. A. Riesenberg, "Changing knowledge and attitudes about skin cancer risk factors in adolescents," Health Psychology, vol. 11, no. 6, pp. 371, 1992. https://doi.org/10.1037/0278-6133.11.6.371
  2. M. E. Celebi, H. A. Kingravi, B. Uddin, H. Iyatomi, Y. A. Aslandogan, W. V. Stoecker and R. H. Moss, "A methodological approach to the classification of dermoscopy images," Computerized Medical Imaging and Graphics, vol. 31, no. 6, pp. 362-373, September, 2007. https://doi.org/10.1016/j.compmedimag.2007.01.003
  3. Q. Abbas, M. E. Celebi and I. F. Garcia, "Hair removal methods: a comparative study for dermoscopy images," Biomedical Signal Processing and Control, vol. 6, no. 4, pp. 395-404, October, 2011. https://doi.org/10.1016/j.bspc.2011.01.003
  4. O. Ronneberger, P. Fischer and T. Brox, "U-net: Convolutional networks for biomedical image segmentation," in Proc of International Conference on Medical Image Computing and Computer-Assisted Intervention, vol. 9351, pp. 234-241, October, 2015.
  5. V. Badrinarayanan, A. Kendall and R. Cipolla, "SegNet: A Deep Convolutional Encoder-Decoder Architecture for Scene Segmentation," IEEE Transactions on Pattern Analysis & Machine Intelligence, vol. 39, no. 12, pp. 2481-2495, December, 2017. https://doi.org/10.1109/TPAMI.2016.2644615
  6. S. Sookpotharom, "Border detection of skin lesion images based on fuzzy C-means thresholding," in Proc. of Genetic and Evolutionary Computing, 2009. WGEC'09. 3rd International Conference on. IEEE, pp. 777-780, October 14 - 17, 2009.
  7. H. Zhou, G. Schaefer, M. E. Celebi, H. Iyatomi, K. A. Norton, T. Liu and F. Lin, "Skin lesion segmentation using an improved snake model," in Proc. of Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE, pp. 1974-1977, November 11, 2010.
  8. C. M. Emre, H. A. Kingravi, H. Iyatomi, A. Y. Alp, W. V. Stoecker, R. H. Moss and S. W. Menzies, "Border detection in dermoscopy images using statistical region merging," Skin Research and Technology, vol. 14, no. 3, pp. 347-353, 2008. https://doi.org/10.1111/j.1600-0846.2008.00301.x
  9. G. Schaefer, M. I. Rajab, M. E. Celebi and H. Iyatomi, "Colour and contrast enhancement for improved skin lesion segmentation," Computerized Medical Imaging and Graphics, vol. 35, no. 2, pp. 99-104, March, 2011. https://doi.org/10.1016/j.compmedimag.2010.08.004
  10. J. Long, E. Shelhamer and T. Darrell, "Fully convolutional networks for semantic segmentation," in Proc. of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431-3440, June 7-12, 2015.
  11. S. Liu, X. Liang, L. Liu, X. Shen, J. Yang, C. Xu and S. Yan, "Matching-CNN meets KNN: Quasi-parametric human parsing," IEEE Computer Vision and Pattern Recognition, pp. 1419-1427, April, 2015.
  12. S. Liu, C. Wang, R. Qian, H. Yu, R. Bao and Y. Sun, "Surveillance Video Parsing with Single Frame Supervision," in Proc. of IEEE Conference on Computer Vision and Pattern Recognition, July, 2017.
  13. X. Liang, S. Liu, X. Shen, J. Yang, L. Liu, J. Dong and S. Yan, "Deep Human Parsing with Active Template Regression," IEEE Transactions on Pattern Analysis & Machine Intelligence, vol. 37, no. 12, pp. 2402-2414, December, 2015. https://doi.org/10.1109/TPAMI.2015.2408360
  14. I. Goodfellow, J. Pouget-Abadie, M. Mirza, B. Xu, D. Warde-Farley, S. Ozair and Y. Bengio, "Generative adversarial nets," Advances in neural information processing systems, pp. 2672-2680, December 08 - 13, 2014.
  15. W. Liu, X. Liu, H. Ma and P. Cheng, "Beyond Human-level License Plate Super-resolution with Progressive Vehicle Search and Domain Priori GAN," ACM Multimedia, October, 2017.
  16. Z. Li and J.Tang, "Weakly supervised deep matrix factorization for social image understanding," IEEE Transactions on Image Processing, vol. 26, no. 1, pp. 276-288, 2017. https://doi.org/10.1109/TIP.2016.2624140
  17. P. Isola, J. Y. Zhu, T. Zhou and A. A. Efros, "Image-to-image translation with conditional adversarial networks," in Proc. of IEEE Conference on Computer Vision and Pattern Recognition, pp. 5967-5976, July, 2017.
  18. P. Luc, C. Couprie, S. Chintala and J. Verbeek, "Semantic segmentation using adversarial networks," arXiv preprint, arXiv:1611.08408, 2016.
  19. W. Liu, T. Mei, Y. Zhang, C. Che and J. Luo, "Multi-task deep visual-semantic embedding for video thumbnail selection," in Proc. of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3707-3715, June, 2015.
  20. Z. Li, J. Liu, J. Tang and H. Lu, "Robust structured subspace learning for data representation," IEEE transactions on pattern analysis and machine intelligence, vol. 37, no. 10, pp. 2085-2098, February, 2015. https://doi.org/10.1109/TPAMI.2015.2400461
  21. X. Mao, Q. Li, H. Xie, R. Y. Lau, Z. Wang and S. P. Smolley, "Least squares generative adversarial networks," in Proc. of IEEE International Conference on Computer Vision, pp. 2813-2821, 2017.
  22. D. Pathak, P. Krahenbuhl, J. Donahue, T. Darrell and A. A. Efros, "Context encoders: Feature learning by inpainting," in Proc. of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 2536-2544, June 27-30, 2016.
  23. S. Ioffe and C. Szegedy, "Batch normalization: Accelerating deep network training by reducing internal covariate shift," in Proc. of International Conference on Machine Learning, pp. 448-456, 2015.
  24. P. Vincent, H. Larochelle, Y. Bengio and P. A. Manzagol, "Extracting and composing robust features with denoising autoencoders," in Proc. of the 25th international conference on Machine learning. ACM, pp. 1096-1103, July 05 - 09, 2008.
  25. N. Srivastava, G. E. Hinton, A. Krizhevsky, I. Sutskever and R. Salakhutdinov, "Dropout: a simple way to prevent neural networks from overfitting," Journal of machine learning research, vol. 15, no. 1,pp. 1929-1958, January, 2014.
  26. C. K. Sonderby, J. Caballero, L. Theis, W. Shi and F. Huszar, "Amortised map inference for image super-resolution," arXiv preprint arXiv:1610.04490, 2016.
  27. A. Radford, L. Metz, and S. Chintala, "Unsupervised Representation Learning with Deep Convolutional Generative Adversarial Networks," Computer Science, 2015.
  28. D. Gutman, N. C. F. Codella, E. Celebi, B. Helba, M. Marchetti, N. Mishra and A. Halpern, "Skin Lesion Analysis toward Melanoma Detection: A Challenge at the International Symposium on Biomedical Imaging (ISBI) 2016, hosted by the International Skin Imaging Collaboration (ISIC)," eprint arXiv:1605.01397. 2016.
  29. J. Davis and M. Goadrich, "The relationship between Precision-Recall and ROC curves," in Proc. of the 23rd international conference on Machine learning, pp. 233-240, June 25-29, 2006.
  30. S. Liu, Y. Sun, D. Zhu, R. Bao, W. Wang, X. Shu and S. Yan, "Face Aging with Contextual Generative Adversarial Nets," in Proc. of the 2017 ACM on Multimedia Conference, pp. 82-90, October, 2017.

Cited by

  1. X-ray Image Segmentation using Multi-task Learning vol.14, pp.3, 2018, https://doi.org/10.3837/tiis.2020.03.011