27세 남자환자에서 발견된 대장의 점액선암종 1례

A Case Report of Colonic Mucinous Adenocarcinoma in 27 Year Old Patient

  • 류우선 (충남대학교 의과대학 내과학교실 소화기내과) ;
  • 김주석 (충남대학교 의과대학 내과학교실 소화기내과) ;
  • 강선형 (충남대학교 의과대학 내과학교실 소화기내과) ;
  • 문희석 (충남대학교 의과대학 내과학교실 소화기내과) ;
  • 성재규 (충남대학교 의과대학 내과학교실 소화기내과) ;
  • 정현용 (충남대학교 의과대학 내과학교실 소화기내과)
  • Woo Sun Rou (Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University College of Medicine) ;
  • Ju Seok Kim (Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University College of Medicine) ;
  • Sun Hyung Kang (Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University College of Medicine) ;
  • Hee Seok Moon (Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University College of Medicine) ;
  • Jae Kyu Sung (Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University College of Medicine) ;
  • Hyun Yong Jeong (Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University College of Medicine)
  • 투고 : 2018.11.13
  • 심사 : 2018.11.28
  • 발행 : 2018.12.31

초록

점액선암종은 암종 내에 점액이 차지하는 용적이 50% 이상인 경우로 정의한다. 점액선암종은 결장직장암의 약 3.9-19% 의 빈도로 보고되고 있으며, 비점액선암종에 비해 평균 연령이 낮고 진행된 상태에서 발견되며 예후가 나쁜 것으로 보고되고 있다. 특히 젊은 연령에서 악성 종양의 빈도가 적기 때문에 악성 종양의 가능성을 간과하여 진단이 늦어지거나 진행된 상태로 발견될 수 있다. 저자들은 장염으로 의뢰되어 대장내시경을 통한 조직검사에서 진단이 되지 않았지만 수술적 절제 후에 점액선암종으로 진단된 1예를 문헌고찰과 함께 보고하는 바이다.

Mucinous adenocarcinoma occurs in 1.6-25.4% of patients with colorectal cancer. We report a case of a 27-year-old man with negative findings on initial colonoscopic biopsy, but finally diagnosed with mucinous adenocarcinoma of the colon. After undergoing an abdominal CT due to persistent abdominal pain, he was transferred to our hospital. The abdominal CT showed a diffuse and irregular wall thickening in the distal transverse colon. Due to the edema and stenosis of colonic wall, it was difficult to insert the colonoscope into the proximal region; a biopsy revealed chronic colitis with lymphofollicular hyperplasia. Transverse colectomy and lymph node dissection were performed. The diagnosis was mucinous adenocarcinoma of approximately 20×4.5 cm. Compared to adenocarcinoma, mucinous adenocarcinoma is found in a younger population with an advanced stage and is less responsive to palliative chemotherapy. Therefore, recalcitrant abdominal pain even in young people warrants early detection through appropriate examinations such as abdominal CT and colonoscopy.

키워드

참고문헌

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