Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Neurolymphomatosis presenting as brachial plexopathy with involvement of cranial nerves

  • Lee, Hye Jung (Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Kim, Keun Soo (Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Song, Pamela (Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Lee, Jae-Jung (Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Sung, Jung-Joon (Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Choi, Kyomin (Department of Neurology, Konkuk University Medical Center) ;
  • Kim, Bohyun (Department of Pathology, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Cho, Joong-Yang (Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine)
  • Received : 2017.06.23
  • Accepted : 2017.09.25
  • Published : 2018.01.31
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Abstract

Neurolymphomatosis (NL) is a rare disease characterized by lymphomatous invasion of the cranial or peripheral nerves by lymphoma. A high suspicion is important due to the various presenting symptoms mandating consideration of many differential diagnoses. We report a case of NL of the cranial nerves and plexus presenting as diplopia, facial palsy, and weakness of the upper and lower limbs in sequence.

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References

  1. Grisariu S, Avni B, Batchelor TT, van den Bent MJ, Bokstein F, Schiff D, et al. Neurolymphomatosis: an International Primary CNS Lymphoma Collaborative Group report. Blood 2010;115:5005-5011. https://doi.org/10.1182/blood-2009-12-258210
  2. Lagarde S, Tabouret E, Matta M, Franques J, Attarian S, Pouget J, et al. Primary neurolymphomatosis diagnosis and treatment: a retrospective study. J Neurol Sci 2014;342:178-181. https://doi.org/10.1016/j.jns.2014.04.030
  3. Misdraji J, Ino Y, Louis DN, Rosenberg AE, Chiocca EA, Harris NL. Primary lymphoma of peripheral nerve: report of four cases. Am J Surg Pathol 2000;24:1257-1265. https://doi.org/10.1097/00000478-200009000-00009
  4. Baehring JM, Damek D, Martin EC, Betensky RA, Hochberg FH. Neurolymphomatosis. Neuro Oncol 2003;5:104-115. https://doi.org/10.1215/15228517-5-2-104
  5. Descamps MJ, Barrett L, Groves M, Yung L, Birch R, Murray NM, et al. Primary sciatic nerve lymphoma: a case report and review of the literature. J Neurol Neurosurg Psychiatry 2006;77:1087-1089. https://doi.org/10.1136/jnnp.2006.087577
  6. Matsue K, Hayama BY, Iwama K, Koyama T, Fujiwara H, Yamakura M, et al. High frequency of neurolymphomatosis as a relapse disease of intravascular large B-cell lymphoma. Cancer 2011;117:4512-4521. https://doi.org/10.1002/cncr.26090
  7. Choi YJ, Shin JA, Kim YH, Cha SJ, Cho JY, Kang SH, et al. Neurolymphomatosis of brachial plexus in patients with non-Hodgkin's lymphoma. Case Rep Oncol Med 2013;2013:492329.
  8. Sakai N, Ito-Yamashita T, Takahashi G, Baba S, Koizumi S, Yamasaki T, et al. Primary neurolymphomatosis of the lower cranial nerves presenting as Dysphagia and hoarseness: a case report. J Neurol Surg Rep 2014;75:e62-e66. https://doi.org/10.1055/s-0033-1363505
  9. Sideras PA, Matthews J, Sakib SM, Ofikwu F, Spektor V. Neurolymphomatosis of the peripheral nervous system: a case report and review of the literature. Clin Imaging 2016;40:1253-1256. https://doi.org/10.1016/j.clinimag.2016.08.014
  10. Shree R, Goyal MK, Modi M, Gaspar BL, Radotra BD, Ahuja CK, et al. The diagnostic dilemma of neurolymphomatosis. J Clin Neurol 2016;12:274-281. https://doi.org/10.3988/jcn.2016.12.3.274