References
- Baba, A., Ohtake, F., Okuno, Y., Yokota, K., Okada, M., Imai, Y., Ni, M., Meyer, C.A., Igarashi, K., Kanno, J., et al. (2011). PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B. Nat. Cell Biol. 13, 668-675. https://doi.org/10.1038/ncb2228
- Badeaux, A.I., and Shi, Y. (2013). Emerging roles for chromatin as a signal integration and storage platform. Nat. Rev. Mol. Cell Biol. 14, 211-224. https://doi.org/10.1038/nrm3545
- Boland, M.J., Nazor, K.L., and Loring, J.F. (2014). Epigenetic regulation of pluripotency and differentiation. Circ. Res. 115, 311-324. https://doi.org/10.1161/CIRCRESAHA.115.301517
- Cai, L., Sutter, B.M., Li, B., and Tu, B.P. (2011). Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes. Mol. Cell 42, 426-437. https://doi.org/10.1016/j.molcel.2011.05.004
- Canto, C., Gerhart-Hines, Z., Feige, J.N., Lagouge, M., Noriega, L., Milne, J.C., Elliott, P.J., Puigserver, P., and Auwerx, J. (2009). AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 458, 1056-1060. https://doi.org/10.1038/nature07813
- Carey, B.W., Finley, L.W., Cross, J.R., Allis, C.D., and Thompson, C.B. (2015). Intracellular alpha-ketoglutarate maintains the pluripotency of embryonic stem cells. Nature 518, 413-416. https://doi.org/10.1038/nature13981
- Cha, T.L., Zhou, B.P., Xia, W., Wu, Y., Yang, C.C., Chen, C.T., Ping, B., Otte, A.P., and Hung, M.C. (2005). Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. Science 310, 306-310. https://doi.org/10.1126/science.1118947
- Chang, H.C., and Guarente, L. (2014). SIRT1 and other sirtuins in metabolism. Trends Endocrinol. Metabol. 25, 138-145. https://doi.org/10.1016/j.tem.2013.12.001
- Hay, N. (2016). Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy? Nat. Rev. Cancer 16, 635-649. https://doi.org/10.1038/nrc.2016.77
- Huang, W.C., and Chen, C.C. (2005). Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. Mol. Cell. Biol. 25, 6592-6602. https://doi.org/10.1128/MCB.25.15.6592-6602.2005
- Hwang, I.Y., Kwak, S., Lee, S., Kim, H., Lee, S.E., Kim, J.H., Kim, Y.A., Jeon, Y.K., Chung, D.H., Jin, X., et al. (2016). Psat1-dependent fluctuations in alpha-Ketoglutarate affect the timing of ESC differentiation. Cell Metabol. 24, 494-501. https://doi.org/10.1016/j.cmet.2016.06.014
- Katoh, Y., Ikura, T., Hoshikawa, Y., Tashiro, S., Ito, T., Ohta, M., Kera, Y., Noda, T., and Igarashi, K. (2011). Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein. Mol. Cell 41, 554-566. https://doi.org/10.1016/j.molcel.2011.02.018
- Kim, J.E., Chen, J., and Lou, Z. (2008). DBC1 is a negative regulator of SIRT1. Nature 451, 583-586. https://doi.org/10.1038/nature06500
- Kooistra, S.M., and Helin, K. (2012). Molecular mechanisms and potential functions of histone demethylases. Nat. Rev. Mol. Cell Biol. 13, 297-311. https://doi.org/10.1038/nrm3327
- Kottakis, F., Nicolay, B.N., Roumane, A., Karnik, R., Gu, H., Nagle, J.M., Boukhali, M., Hayward, M.C., Li, Y.Y., Chen, T., et al. (2016). LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature 539, 390-395. https://doi.org/10.1038/nature20132
- Kryukov, G.V., Wilson, F.H., Ruth, J.R., Paulk, J., Tsherniak, A., Marlow, S.E., Vazquez, F., Weir, B.A., Fitzgerald, M.E., Tanaka, M., et al. (2016). MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells. Science 351, 1214-1218. https://doi.org/10.1126/science.aad5214
- Lau, A.W., Liu, P., Inuzuka, H., and Gao, D. (2014). SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation. Am. J. Cancer Res. 4, 245-255.
- Lee, J.V., Carrer, A., Shah, S., Snyder, N.W., Wei, S., Venneti, S., Worth, A.J., Yuan, Z.F., Lim, H.W., Liu, S., et al. (2014). Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell Metabol. 20, 306-319. https://doi.org/10.1016/j.cmet.2014.06.004
- Li, S., Swanson, S.K., Gogol, M., Florens, L., Washburn, M.P., Workman, J.L., and Suganuma, T. (2015). Serine and SAM responsive complex SESAME regulates histone modification crosstalk by sensing cellular metabolism. Mol. Cell 60, 408-421. https://doi.org/10.1016/j.molcel.2015.09.024
- Liu, F., Zhao, X., Perna, F., Wang, L., Koppikar, P., Abdel-Wahab, O., Harr, M.W., Levine, R.L., Xu, H., Tefferi, A., et al. (2011). JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation. Cancer Cell 19, 283-294. https://doi.org/10.1016/j.ccr.2010.12.020
- Mattaini, K.R., Sullivan, M.R., and Vander Heiden, M.G. (2016). The importance of serine metabolism in cancer. J. Cell Biol. 214, 249-257. https://doi.org/10.1083/jcb.201604085
- Mentch, S.J., and Locasale, J.W. (2016). One-carbon metabolism and epigenetics: understanding the specificity. Ann. New York Acad. Sci. 1363, 91-98. https://doi.org/10.1111/nyas.12956
- Mentch, S.J., Mehrmohamadi, M., Huang, L., Liu, X., Gupta, D., Mattocks, D., Gomez Padilla, P., Ables, G., Bamman, M.M., Thalacker-Mercer, A.E., et al. (2015). Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism. Cell Metabol. 22, 861-873. https://doi.org/10.1016/j.cmet.2015.08.024
- Mews, P., Donahue, G., Drake, A.M., Luczak, V., Abel, T., and Berger, S.L. (2017). Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory. Nature 546, 381-386. https://doi.org/10.1038/nature22405
- Mihaylova, M.M., and Shaw, R.J. (2011). The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat. Cell Biol. 13, 1016-1023. https://doi.org/10.1038/ncb2329
- Nin, V., Escande, C., Chini, C.C., Giri, S., Camacho-Pereira, J., Matalonga, J., Lou, Z., and Chini, E.N. (2012). Role of deleted in breast cancer 1 (DBC1). protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase. J. Biol. Chem. 287, 23489-23501. https://doi.org/10.1074/jbc.M112.365874
- Pan, M., Reid, M.A., Lowman, X.H., Kulkarni, R.P., Tran, T.Q., Liu, X., Yang, Y., Hernandez-Davies, J.E., Rosales, K.K., Li, H., et al. (2016). Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation. Nat. Cell Biol. 18, 1090-1101. https://doi.org/10.1038/ncb3410
- Pavlova, N.N., and Thompson, C.B. (2016). The emerging hallmarks of cancer metabolism. Cell Metabol. 23, 27-47. https://doi.org/10.1016/j.cmet.2015.12.006
- Portela, A., and Esteller, M. (2010). Epigenetic modifications and human disease. Nat. Biotechnol. 28, 1057-1068. https://doi.org/10.1038/nbt.1685
- Reid, M.A., Dai, Z., and Locasale, J.W. (2017). The impact of cellular metabolism on chromatin dynamics and epigenetics. Nat. Cell Biol. 19, 1298-1306. https://doi.org/10.1038/ncb3629
- Shyh-Chang, N., Locasale, J.W., Lyssiotis, C.A., Zheng, Y., Teo, R.Y., Ratanasirintrawoot, S., Zhang, J., Onder, T., Unternaehrer, J.J., Zhu, H., et al. (2013). Influence of threonine metabolism on Sadenosylmethionine and histone methylation. Science 339, 222-226. https://doi.org/10.1126/science.1226603
- Stopa, N., Krebs, J.E., and Shechter, D. (2015). The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond. Cell. Mol. Life Sci. 72, 2041-2059. https://doi.org/10.1007/s00018-015-1847-9
- Sun, L., Huang, Y., Wei, Q., Tong, X., Cai, R., Nalepa, G., and Ye, X. (2015). Cyclin E-CDK2 protein phosphorylates plant homeodomain finger protein 8 (PHF8). and regulates its function in the cell cycle. J. Biol. Chem. 290, 4075-4085. https://doi.org/10.1074/jbc.M114.602532
- Sutendra, G., Kinnaird, A., Dromparis, P., Paulin, R., Stenson, T.H., Haromy, A., Hashimoto, K., Zhang, N., Flaim, E., and Michelakis, E.D. (2014). A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation. Cell 158, 84-97. https://doi.org/10.1016/j.cell.2014.04.046
- TeSlaa, T., Chaikovsky, A.C., Lipchina, I., Escobar, S.L., Hochedlinger, K., Huang, J., Graeber, T.G., Braas, D., and Teitell, M.A. (2016). alpha-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells. Cell Metabol. 24, 485-493. https://doi.org/10.1016/j.cmet.2016.07.002
- Wellen, K.E., Hatzivassiliou, G., Sachdeva, U.M., Bui, T.V., Cross, J.R., and Thompson, C.B. (2009). ATP-citrate lyase links cellular metabolism to histone acetylation. Science 324, 1076-1080. https://doi.org/10.1126/science.1164097
- Wise, D.R., and Thompson, C.B. (2010). Glutamine addiction: a new therapeutic target in cancer. Trends Biochem. Sci. 35, 427-433. https://doi.org/10.1016/j.tibs.2010.05.003
- Zhao, W., Kruse, J.P., Tang, Y., Jung, S.Y., Qin, J., and Gu, W. (2008). Negative regulation of the deacetylase SIRT1 by DBC1. Nature 451, 587-590. https://doi.org/10.1038/nature06515
Cited by
- Reciprocal Regulation of Metabolic Reprogramming and Epigenetic Modifications in Cancer vol.9, pp.1664-8021, 2018, https://doi.org/10.3389/fgene.2018.00394
- The Emerging Epigenetic Role of CD8+T Cells in Autoimmune Diseases: A Systematic Review vol.10, pp.None, 2018, https://doi.org/10.3389/fimmu.2019.00856
- Dephosphorylation of p53 Ser 392 Enhances Trimethylation of Histone H3 Lys 9 via SUV39h1 Stabilization in CK2 Downregulation-Mediated Senescence vol.42, pp.11, 2018, https://doi.org/10.14348/molcells.2019.0018
- A complex interplay between SAM synthetase and the epigenetic regulator SIN3 controls metabolism and transcription vol.295, pp.2, 2018, https://doi.org/10.1074/jbc.ra119.010032
- Von Hippel–Lindau tumor suppressor (VHL) stimulates TOR signaling by interacting with phosphoinositide 3-kinase (PI3K) vol.295, pp.8, 2018, https://doi.org/10.1074/jbc.ra119.011596
- Metabolic choreography of gene expression: nutrient transactions with the epigenome vol.45, pp.1, 2018, https://doi.org/10.1007/s12038-019-9987-y
- Regulation of Gene Expression and the Elucidative Role of CRISPR-Based Epigenetic Modifiers and CRISPR-Induced Chromosome Conformational Changes vol.4, pp.1, 2018, https://doi.org/10.1089/crispr.2020.0108
- Early Life Stress and Metabolic Plasticity of Brain Cells: Impact on Neurogenesis and Angiogenesis vol.9, pp.9, 2018, https://doi.org/10.3390/biomedicines9091092
- Emerging roles of epigenetic regulation in obesity and metabolic disease vol.297, pp.5, 2018, https://doi.org/10.1016/j.jbc.2021.101296