The Korean journal of internal medicine

The Korean Association of Internal Medicine (대한내과학회)
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Middle East respiratory syndrome: what we learned from the 2015 outbreak in the Republic of Korea

  • Oh, Myoung-don (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Park, Wan Beom (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Park, Sang-Won (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Choe, Pyoeng Gyun (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Bang, Ji Hwan (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Song, Kyoung-Ho (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Kim, Eu Suk (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Kim, Hong Bin (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Kim, Nam Joong (Department of Internal Medicine, Seoul National University College of Medicine)
  • Received : 2018.02.05
  • Accepted : 2018.02.13
  • Published : 2018.03.01
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Abstract

Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first isolated from a patient with severe pneumonia in 2012. The 2015 Korea outbreak of MERSCoV involved 186 cases, including 38 fatalities. A total of 83% of transmission events were due to five superspreaders, and 44% of the 186 MERS cases were the patients who had been exposed in nosocomial transmission at 16 hospitals. The epidemic lasted for 2 months and the government quarantined 16,993 individuals for 14 days to control the outbreak. This outbreak provides a unique opportunity to fill the gap in our knowledge of MERS-CoV infection. Therefore, in this paper, we review the literature on epidemiology, virology, clinical features, and prevention of MERS-CoV, which were acquired from the 2015 Korea outbreak of MERSCoV.

Keywords

References

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