Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
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Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement

  • Lee, Kanghoon (Department of Thoracic and Cardiovascular Surgery, Korea University Guro Hospital, Korea University College of Medicine) ;
  • Kim, Hyeong Ryul (Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Roh, Jin (Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Ok, You Jung (Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jeon, Bo Bae (Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Young Woong (Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine)
  • Received : 2017.09.13
  • Accepted : 2017.10.07
  • Published : 2018.06.05
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Abstract

Erdheim-Chester disease (ECD) is a form of non-Langerhans cell histiocytosis that most commonly involves the skeletal system. We report an unusual case of ECD presenting as an anterior mediastinal tumor without skeletal involvement. A 60-year-old man with no remarkable medical history was referred for evaluation of a mediastinal mass. The patient underwent surgical excision of the tumor via video-assisted thoracoscopic surgery. Histologic examination revealed marked proliferation of atypical histiocytes with sclerosis, and the results of immunohistochemical staining were suggestive of ECD.

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References

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