Journal of the Korean Society of Radiology (한국방사선학회논문지)

The Korean Society of Radiology (한국방사선학회)
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Relationship between 18FDG Uptake Rate and CT Number in Fatty Liver on PET-CT

PET-CT 검사에서 지방간의 18FDG 섭취율과 CT Number의 관련성 연구

  • Lee, Eun-Hyeng (Department of Radiology, National Police Hostpital) ;
  • Seok, Jong-Min (Department of Radiology, National Police Hostpital) ;
  • Jeon, Woo-Jin (Department of Radiology, National Police Hostpital) ;
  • Ko, Eun-Ju (Department of International Radiological Science, Hallym University of Graduate Studies) ;
  • Lee, Jin (Department of International Radiological Science, Hallym University of Graduate Studies)
  • 이은형 (국립경찰병원 영상의학과) ;
  • 석종민 (국립경찰병원 영상의학과) ;
  • 전우진 (국립경찰병원 영상의학과) ;
  • 고은주 (한림국제대학원대학교 국제방사선학과) ;
  • 이진 (한림국제대학원대학교 국제방사선학과)
  • Received : 2018.01.20
  • Accepted : 2018.04.30
  • Published : 2018.04.30
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Abstract

The purpose of this study is to provide the basic information for diagnosis and treatment of fatty liver by investigating the relationship of the body $^{18}FDG$ uptake and CT Number in patients with fatty liver. This study was conducted on patients who were admitted to the N hospital from January 2014 to October 2015 underwent PET-CT. This result, the probability of fatty liver was 5 times higher in male. The $^{18}FDG$ uptaking were increased by more than 1.000 times respectively in the Liver RT, Middle liver, Liver LT from patients with fatty liver (p <.05). And the CT Number were decreased by 0.93, 0.88, and 0.92 times respectively in Liver RT, Middle liver, Liver LT from patients with fatty liver (p <.05). In conclusion, significant changes of $^{18}FDG$ uptake rate and CT number according to fatty liver provide reliable information for diagnosis and treatment of fatty liver patients. And it can be used as a basic data for the study of fatty liver predictability.

본 연구의 목적은 지방간 환자의 간내 $^{18}FDG$ 섭취율과 CT 계수값(Number)의 관련성을 연구하여, 지방간 환자의 진단 및 치료에 도움이 되는 기초 정보 제공을 위하여 시행되었다. 본 연구의 데이터는 2014년 1월부터 2015년 10월까지 서울소재 N 종합병원에 내원하여 PET-CT 검사를 시행한 환자를 대상으로 데이터를 분석하였다. 연구결과, 지방간일 확률은 남자가 여자보다 5배 높았으며(p<.05), 간의 우측, 중간, 좌측에서 $^{18}FDG$ 섭취율이 각각 1.000배이상 증가하고(p<.05), CT 계수값은 각각 0.93배, 0.88배, 0.92배 감소하였다(p<.05). 결론적으로 $^{18}FDG$ 섭취율과 CT Number값의 지방간 유무에 따른 유의미한 변화는 지방간 환자의 진단 및 치료에 신뢰할만한 정보를 제공하고, 지방간 예측성 연구를 위한 기초자료로 활용 될 수 있을 것이다.

Keywords

References

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