한국응용과학기술학회지 (Journal of the Korean Applied Science and Technology)

  • 제35권1호
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  • Pages.141-150
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  • 2018
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  • 1225-9098(pISSN)
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  • 2288-1069(eISSN)
한국응용과학기술학회 (The Korean Society of Applied Science and Technology)
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메카니즘 해석을 통해 바라본 홍합접착제 연구동향

Brief Review on Mussel Adhesives by Evaluating Its Adhesion and Cohesion Mechanisms

  • 강병언 (인하공업전문대학 화공환경과) ;
  • 이재성 (인하공업전문대학 화공환경과) ;
  • 오경석 (인하공업전문대학 화공환경과)
  • Kang, Byoung-Un (Department of Chemical and Environmental Technology, Inha Technical College) ;
  • Lee, Jae-Sung (Department of Chemical and Environmental Technology, Inha Technical College) ;
  • Oh, Kyeong-Seok (Department of Chemical and Environmental Technology, Inha Technical College)
  • 투고 : 2018.02.05
  • 심사 : 2018.03.06
  • 발행 : 2018.03.30
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⟨ 이전 논문 다음 논문 ⟩

초록

홍합 족사 단백질은 수분이 있는 표면에서도 강한 접착력을 가진다. 홍합 연구에 대표가 되는 marine blue mussel을 통해 9가지 단백질의 구조와 기능이 보고되었으며, 이 단백질들은 홍합 족사를 구성하는 실(threads)과 플래크(plaques)를 형성한다. 알려진 바에 의하면, 히드록시기 2개가 포함된 카테콜 기능기를 가진 DOPA 물질이 계면접착(adhesion)과 내부결합(cohesion) 과정에서 중요한 역할을 하는 것으로 알려져 있다. 본 논문에서는, 최근 10년간 활발히 연구된 계면접착과 내부응력 메카니즘에 대해 소개하고 평가하였다. 또한, 접착력을 갖는 기능기를 활용한 발전된 접착소재의 개발, 바이오접착제와 의료용 소재로 응용가능성에 대해 살펴보았다. 홍합 단백질이 다시 관심의 대상이 되면서, 바이오소재로 사용될 가능성이 커지고 있음이 주목된다.

Mussel byssal protein has strong adhesive capability even in wet surface. It has been reported that nine proteins in marine blue mussel, often referred to a representative mussel, contribute to form mussel byssal threads and plaques. DOPA containing two hydroxy groups called cathecol is recognized that it plays a major role in adhesion as well as cohesion process within byssal structure. In this paper, adhesion and cohesion mechanisms were introduced and evaluated by supportive literature published during last decade. Diverse applications of cathecol chemicals were also examined in terms of innovative adhesive, bioadhesive and challenging material for tissue engineering. It is noticeable that reconsideration of mussel proteins could provide the various opportunities as biomaterials.

키워드

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