The Korean Journal of Nuclear Medicine Technology (핵의학기술)

The Korean Society of Nuclear Medicine Technology (대한핵의학기술학회)
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Clinical Study of Simultaneous Acquisition Rest 99mTc-sestaMIBI/Stress 201Tl Dual-Isotope Myocardial Perfusion Imaging with a Solid-State Dedicated Cardiac Gamma Camera

반도체 심근 전용 감마카메라를 이용한 Rest 99mTc-sestaMIBI/Stress201Tl 이중 동위원소 심근 관류 동시 스캔에 관한 임상적 고찰

  • Bahn, Young-Kag (Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System) ;
  • Kim, Dong-Heui (Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System) ;
  • Choi, Yong-Hoon (Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System) ;
  • Kang, Chun-Koo (Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System) ;
  • Kim, Jae-Sam (Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System)
  • 반영각 (연세의료원 세브란스병원, 핵의학과) ;
  • 김동희 (연세의료원 세브란스병원, 핵의학과) ;
  • 최용훈 (연세의료원 세브란스병원, 핵의학과) ;
  • 강천구 (연세의료원 세브란스병원, 핵의학과) ;
  • 김재삼 (연세의료원 세브란스병원, 핵의학과)
  • Received : 2018.10.01
  • Accepted : 2018.10.11
  • Published : 2018.10.31
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Abstract

Purpose The purpose of this study is to investigate the simultaneous dual isotope (SDI) myocardial perfusion scan that can be performed in a short time using a semiconductor gamma camera. Materials and Methods Of the 86 patients who underwent Rest/Stress $^{99m}TC$-sestaMIBI 1-day myocardial perfusion scan and Rest $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ simultaneous dual isotope myocardial perfusion scan using a heart-only gamma camera, the test results were the same, 36 patients who did not show any change in the clinical outcome. Quantitative values were statistically analyzed using a QPS program to confirm the correlation between the images of the two examinations. Results Rest/Stress $^{99m}TC$-sestaMIBI simultaneous dual myocardial perfusion scans and $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ double-isotope myocardial perfusion scans were analyzed for Summed score. The $R^2$ value of the Rest summed score (RSS) was 0.91 and the $R^2$ value of the stress summed score (SSS) was 0.71. Conclusion The $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ simultaneous dual isotope scan confirmed its correlation with the previous day's test. The $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ simultaneous dual isotope scan can be completed in approximately 30minutes. It maybe clinically useful for patients who need short examination time such as emergency patients or elderly patients.

본 연구는 반도체 심근 전용 감마카메라를 이용하여 단시간에 검사가 가능한 이중 동위원소 심근 관류 동시스캔에 대해 임상적으로 연구 해보고자 한다. 심장 전용 감마카메라를 사용하여 Rest/Stress $^{99m}TC$-sestaMIBI 당일 심근관류 스캔과 Rest $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ 이중 동위원소 심근 관류 동시 스캔을 같이 검사한 86명의 환자 중 검사 결과가 동일하고 임상적으로 심장질환의 변화가 없는 환자 36명을 대상으로 분석 했다. 두 검사의 영상의 상관성을 확인하기 위해 QPS 프로그램을 이용하여 정량적 값을 통계적으로 분석 했다. Rest/Stress $^{99m}TC$-sestaMIBI 당일 심근관류 스캔과 $^{99m}TC$-sesta MIBI/Stress $^{201}Tl$ 이중 동위원소 심근 관류 동시 스캔을 summed score에서 상관도를 분석했다. RSS의 $R^2$ 값은 0.91로 나왔고, SSS의 $R^2$ 값은 0.71로 나왔다. $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ 이중 동위원소 동시 검사는 기존 당일 검사와 상관성을 확인했다. $^{99m}TC$-sestaMIBI/Stress $^{201}Tl$ 이중 동위원소 동시 검사는 검사시간이 약 30분만에 완료가 가능하다. 응급환자나 고령의 환자 등 짧은 검사시간이 필요한 환자에게 임상적으로 도움이 될 것으로 사료된다.

Keywords

References

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