References
- Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin 2016;66:7-30. https://doi.org/10.3322/caac.21332
- Niraula S, Ocana A. Mechanism of drug resistance in relation to site of metastasis: meta-analyses of randomized controlled trials in advanced breast cancer according to anticancer strategy. Cancer Treat Rev 2016;50:168-74. https://doi.org/10.1016/j.ctrv.2016.09.011
- Li C, Yang L, Zhang D, Jiang W. Systematic review and meta-analysis suggest that dietary cholesterol intake increases risk of breast cancer. Nutr Res 2016;36:627-35. https://doi.org/10.1016/j.nutres.2016.04.009
- Safarzadeh E, Sandoghchian Shotorbani S, Baradaran B. Herbal medicine as inducers of apoptosis in cancer treatment. Adv Pharm Bull 2014;4:421-7.
- Gali-Muhtasib H, Hmadi R, Kareh M, Tohme R, Darwiche N. Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis. Apoptosis 2015;20:1531-62. https://doi.org/10.1007/s10495-015-1169-2
- Bonofiglio D, Giordano C, De Amicis F, Lanzino M, Ando S. Natural products as promising antitumoral agents in breast cancer: mechanisms of action and molecular targets. Mini Rev Med Chem 2016;16:596-604. https://doi.org/10.2174/1389557515666150709110959
- Wang CY, Bai XY, Wang CH. Traditional Chinese medicine: a treasured natural resource of anticancer drug research and development. Am J Chin Med 2014;42:543-59.
- Ming-Hua C, Bao-Hua Z, Lei Y. Mechanisms of anorexia cancer cachexia syndrome and potential benefits of traditional medicine and natural herbs. Curr Pharm Biotechnol 2016;17:1147-52. https://doi.org/10.2174/1389201017666161018123311
- Min KY, Kim HJ, Lee KA, Kim KT, Paik HD. Antimicrobial activity of acid-hydrolyzed Citrus unshiu peel extract in milk. J Dairy Sci 2014;97:1955-60. https://doi.org/10.3168/jds.2013-7390
- Park HJ, Jung UJ, Cho SJ, Jung HK, Shim S, Choi MS. Citrus unshiu peel extract ameliorates hyperglycemia and hepatic steatosis by altering inflammation and hepatic glucose- and lipid-regulating enzymes in db/db mice. J Nutr Biochem 2013;24:419-27. https://doi.org/10.1016/j.jnutbio.2011.12.009
- Oh YC, Cho WK, Jeong YH, Im GY, Yang MC, Hwang YH, Ma JY. Anti-inflammatory effect of Citrus unshiu peel in LPS-stimulated RAW 264.7 macrophage cells. Am J Chin Med 2012;40:611-29. https://doi.org/10.1142/S0192415X12500462
- Suzuki M, Sasaki K, Yoshizaki F, Oguchi K, Fujisawa M, Cyong JC. Anti-hepatitis C virus effect of Citrus unshiu peel and its active ingredient nobiletin. Am J Chin Med 2005;33:87-94. https://doi.org/10.1142/S0192415X05002680
- Lee S, Ra J, Song JY, Gwak C, Kwon HJ, Yim SV, Hong SP, Kim J, Lee KH, Cho JJ, Park YS, Park CS, Ahn HJ. Extracts from Citrus unshiu promote immune-mediated inhibition of tumor growth in a murine renal cell carcinoma model. J Ethnopharmacol 2011;133:973-9. https://doi.org/10.1016/j.jep.2010.07.018
- Kim A, Im M, Gu MJ, Ma JY. Citrus unshiu peel extract alleviates cancer-induced weight loss in mice bearing CT-26 adenocarcinoma. Sci Rep 2016;6:24214. https://doi.org/10.1038/srep24214
- Jin H, Lee WS, Yun JW, Jung JH, Yi SM, Kim HJ, Choi YH, Kim G, Jung JM, Ryu CH, Shin SC, Hong SC. Flavonoids from Citrus unshiu Marc. inhibit cancer cell adhesion to endothelial cells by selective inhibition of VCAM-1. Oncol Rep 2013;30:2336-42. https://doi.org/10.3892/or.2013.2711
- Park HR, Park SB, Hong HD, Suh HJ, Shin KS. Structural elucidation of anti-metastatic rhamnogalacturonan II from the pectinase digest of citrus peels (Citrus unshiu). Int J Biol Macromol 2017;94:161-9.
- Lee PY, Park BC, Chi SW, Bae KH, Kim S, Cho S, Kang S, Kim JH, Park SG. Histone H4 is cleaved by granzyme A during staurosporineinduced cell death in B-lymphoid Raji cells. BMB Rep 2016;49:560-5. https://doi.org/10.5483/BMBRep.2016.49.10.105
- You MK, Kim HJ, Rhyu J, Kim HA. Pear pomace ethanol extract improves insulin resistance through enhancement of insulin signaling pathway without lipid accumulation. Nutr Res Pract 2017;11:198-205. https://doi.org/10.4162/nrp.2017.11.3.198
- Kim HB, Yoo BS. Propolis inhibits UVA-induced apoptosis of human keratinocyte HaCaT cells by scavenging ROS. Toxicol Res 2016;32:345-51. https://doi.org/10.5487/TR.2016.32.4.345
- Fulda S, Debatin KM. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 2006;25:4798-811. https://doi.org/10.1038/sj.onc.1209608
- Nakajima YI, Kuranaga E. Caspase-dependent non-apoptotic processes in development. Cell Death Differ 2017;24:1422-30. https://doi.org/10.1038/cdd.2017.36
- Decker P, Muller S. Modulating poly (ADP-ribose) polymerase activity: potential for the prevention and therapy of pathogenic situations involving DNA damage and oxidative stress. Curr Pharm Biotechnol 2002;3:275-83.
- Hata AN, Engelman JA, Faber AC. The BCL2 family: Key mediators of the apoptotic response to targeted anticancer therapeutics. Cancer Discov 2015;5:475-87.
- Kaminskyy VO, Zhivotovsky B. Free radicals in cross talk between autophagy and apoptosis. Antioxid Redox Signal 2014;21:86-102. https://doi.org/10.1089/ars.2013.5746
- Yang Y, Karakhanova S, Hartwig W, D'Haese JG, Philippov PP, Werner J, Bazhin AV. Mitochondria and mitochondrial ROS in cancer: novel targets for anticancer therapy. J Cell Physiol 2016;231:2570-81. https://doi.org/10.1002/jcp.25349
- Kim J, Kim J, Bae JS. ROS homeostasis and metabolism: a critical liaison for cancer therapy. Exp Mol Med 2016;48:e269. https://doi.org/10.1038/emm.2016.119
- Kim B, Song YS. Mitochondrial dynamics altered by oxidative stress in cancer. Free Radic Res 2016;50:1065-70. https://doi.org/10.1080/10715762.2016.1210141
Cited by
- Mitochondrial functions and melatonin: a tour of the reproductive cancers pp.1420-9071, 2019, https://doi.org/10.1007/s00018-018-2963-0
- B16F10 흑색종 세포의 이동과 침윤에 미치는 동의보감 "유암" 처방에 근거한 한약복합처방들의 영향 vol.26, pp.3, 2018, https://doi.org/10.14374/hfs.2018.26.3.223
- Protective Effects of Nargenicin A1 against Tacrolimus-Induced Oxidative Stress in Hirame Natural Embryo Cells vol.16, pp.6, 2018, https://doi.org/10.3390/ijerph16061044
- Protective Effects of Fermented Oyster Extract against RANKL-Induced Osteoclastogenesis through Scavenging ROS Generation in RAW 264.7 Cells vol.20, pp.6, 2018, https://doi.org/10.3390/ijms20061439
- Citrus unshiu peel suppress the metastatic potential of murine melanoma B16F10 cells in vitro and in vivo vol.33, pp.12, 2018, https://doi.org/10.1002/ptr.6497
- Semi-Continuous Subcritical Water Extraction of Flavonoids from Citrus unshiu Peel: Their Antioxidant and Enzyme Inhibitory Activities vol.9, pp.5, 2020, https://doi.org/10.3390/antiox9050360
- Extraction of flavanones from immature Citrus unshiu pomace: process optimization and antioxidant evaluation vol.10, pp.1, 2020, https://doi.org/10.1038/s41598-020-76965-8
- Neohesperidin Induces Cell Cycle Arrest, Apoptosis, and Autophagy via the ROS/JNK Signaling Pathway in Human Osteosarcoma Cells vol.49, pp.5, 2018, https://doi.org/10.1142/s0192415x21500609
- Chloroform extract of Citrus unshiu Markovich peel induces apoptosis and inhibits stemness in HeLa human cervical cancer cells vol.23, pp.1, 2018, https://doi.org/10.3892/mmr.2020.11727
- Chemical characterization and in vitro immunomodulatory effects of different extracts of moss Hedwigia ciliata (Hedw.) P. Beauv. from the Vršačke Planine Mts., Serbia vol.16, pp.2, 2018, https://doi.org/10.1371/journal.pone.0246810
- Organic Acid-Catalyzed Subcritical Water Hydrolysis of Immature Citrus unshiu Pomace vol.11, pp.1, 2022, https://doi.org/10.3390/foods11010018