Journal of Korean Society of Water and Wastewater (상하수도학회지)

The Korean Society of Water and Wastewater (대한상하수도학회)
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Evaluation and application of pretreatment methods for pharmaceuticals and personal care products in the solid phase of sewage samples

하수처리시설 고상시료 중 잔류의약물질 분석을 위한 전처리법 평가 및 적용

  • Park, Junwon (National Institute of Environmental Research, Water Supply and Sewerage Research Division) ;
  • Kim, Changsoo (National Institute of Environmental Research, Water Supply and Sewerage Research Division) ;
  • Ju, Byoungkyu (National Institute of Environmental Research, Water Supply and Sewerage Research Division) ;
  • Lee, Wonseok (National Institute of Environmental Research, Water Supply and Sewerage Research Division) ;
  • Chung, Hyenmi (National Institute of Environmental Research, Water Supply and Sewerage Research Division) ;
  • Jeong, Dong-Hwan (National Institute of Environmental Research, Water Supply and Sewerage Research Division)
  • 박준원 (국립환경과학원 상하수도연구과) ;
  • 김창수 (국립환경과학원 상하수도연구과) ;
  • 주병규 (국립환경과학원 상하수도연구과) ;
  • 이원석 (국립환경과학원 상하수도연구과) ;
  • 정현미 (국립환경과학원 상하수도연구과) ;
  • 정동환 (국립환경과학원 상하수도연구과)
  • Received : 2018.10.08
  • Accepted : 2018.11.26
  • Published : 2018.12.17
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Abstract

The aim of this study was to evaluate pretreatment methods for 27 pharmaceuticals and personal care products (PPCPs) in various sewage samples using a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) and online solid-phase extraction with LC-MS/MS. Extraction efficiencies of PPCPs in the solid phase under different experimental conditions were evaluated, showing that the highest recoveries were obtained with the addition of sodium sulfate and ethylenediaminetetraacetic acid disodium salt dehydrate in acidified conditions. The recoveries of target compounds ranged from 91 to 117.2% for liquid samples and from 61.3 to 137.2% for solid samples, with a good precision. The methods under development were applied to sewage samples collected in two sewage treatment plants (STPs) to determine PPCPs in liquid and solid phases. Out of 27 PPCPs, more than 19 compounds were detected in liquid samples (i.e., influent and effluent) of two STPs, with concentration ranges of LOQ-33,152 ng/L in influents and LOQ-4,523 ng/L in effluents, respectively. In addition, some PPCPs such as acetylsalicylic acid, ibuprofen, and ofloxacin were detected at high concentrations in activated sludge as well as in excess sludge. This methodology was successfully applied to sewage samples for the determination of the target compounds in STPs.

Keywords

References

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