Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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Ehrlichia ewingii infection in a dog from South Korea - A case report

  • Han, Jae-Ik (Laboratory of Wildlife Medicine/Diseases, College of Veterinary Medicine, Chonbuk National University) ;
  • Na, Ki-Jeong (Laboratory of Veterinary Laboratory Medicine, College of Veterinary Medicine, Chungbuk National University)
  • Received : 2018.05.16
  • Accepted : 2018.12.01
  • Published : 2018.12.30
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Abstract

The report describes a case of natural E. ewingii infection confirmed by microscopic examination and molecular analyses in a domestic dog with acute lameness. After the diagnosis, the dog was successfully treated with oral doxycycline. To authors' knowledge, this is the first case report of natural E. ewingii infection in dogs in South Korea.

Keywords

GCOSBX_2018_v41n4_277_f0001.png 이미지

Fig. 1. Perpheral blood smear showing in tracytoplasmic morula inthe neutrophil. Wright-Giemsa stain, ×100 objective.

References

  1. Anderson BE, Greene CE, Jones DC, Dawson JE. 1992. Ehrlichia ewingii sp. nov., the etiologic agent of canine granulocytic ehrlichiosis. Int J Syst Bacteriol 42: 299-302. https://doi.org/10.1099/00207713-42-2-299
  2. Dawson JE, Biggie KL, Warner CK, Cookson K, Jenkins S, Levine JF, Olson JG. 1996. Polymerase chain reaction evidence of Ehrlichia chaffeensis, an etiologic agent of human ehrlichiosis, in dogs from southeast Virginia. Am J Vet Res 57: 1175-1179.
  3. Doyle CK, Labruna MB, Breitschwerdt EB, Tang YW, Corstvet RE, Hegarty BC, Bloch KC, Li P, Walker DH, McBride JW. 2005. Detection of medically important Ehrlichia by quantitative multicolor taqman real-time polymerase chain reaction of the dsb gene. J Mol Diag 7: 504-510. https://doi.org/10.1016/S1525-1578(10)60581-8
  4. Goldman EE, Breitschwerdt EB, Grindem CB, Hegarty BC, Walls JJ, Dumler JS. 1998. Granulocytic ehrlichiosis in dogs from North Carolina and Virginia. J Vet Intern Med 12: 61-70. https://doi.org/10.1111/j.1939-1676.1998.tb02096.x
  5. Kim CM, Yi YH, Yu DH, Lee MJ, Cho MR, Desai AR, Shringi S, Klein TA, Kim HC, Song JW, Baek LJ, Chong ST, O’Guinn ML, Lee JS, Lee IY, Park JH, Foley J, Chae JS. 2006. Tick-borne rickettsial pathogens in ticks and small mammals in Korea. Appl Environ Microbiol 72: 5766-5776. https://doi.org/10.1128/AEM.00431-06
  6. Liddell AM, Stockham SL, Scott MA, Sumner JW, Paddock CD, Gaudreault-Keener M, Arens MQ, Storch GA. 2003. Predominance of Ehrlichia ewingii in Missouri dog. J Clin Microbiol 41: 4617-4622. https://doi.org/10.1128/JCM.41.10.4617-4622.2003
  7. Murphy GL, Ewing SA, Whitworth LC, Fox JC, Kocan AA. 1998. A molecular and serologic survey of Ehrlichia canis, E. chaffeensis, and E. ewingii in dogs and ticks from Oklahom. Vet Parasitol 79: 325-339. https://doi.org/10.1016/S0304-4017(98)00179-4
  8. Ndip LM, Ndip RN, Esemu SN, Dickmu VL, Fokam EB, Walker DH, McBride JW. 2005. Ehrlichial infection in Cameroonian canines by Ehrlichia canis and Ehrlichia ewingii. Vet Microbiol 111: 59-66. https://doi.org/10.1016/j.vetmic.2005.08.010
  9. Rikihisa Y. 2006. New findings on members of the family Anaplasmataceae of veterinary importance. Ann N Y Acad Sci 1078: 438-445. https://doi.org/10.1196/annals.1374.083
  10. Santos HA, Pires MS, Vilela JAR, Santos TM, Faccini JLH, Baldani CD, Thome SMG, Sanavria A, Massard CL. 2011. Detection of Anaplasma phagocytophilum in Brazilian dogs by real-time polymerase chain reaction. J Vet Diagn Invest 23: 770-774. https://doi.org/10.1177/1040638711406974
  11. Schaefer JJ, Needham GR, Bremer WG, Rikihisa Y, Ewing SA, Stich RW. 2007. Tick acquisition of Ehrlichia canis from dogs treated with doxycycline hyclate. Antimicrob Agents Chemother 9: 3394-3396.
  12. Stockham SL, Schmidt DA, Curtis KS, Schauf BG, Tyler JW, Simpson ST. 1992. Evaluation of granulocytic ehrlichiosis in dogs of Missouri, including serologic status of Ehrlichia canis, Ehrlichia equi, and Borrelia burgodorferi. Am J Vet Res 53: 63-68.
  13. Zahler M, Rinder H, Gothe R. 2000. Detection of a new pathogenic Babesia microti-like species in dogs. Vet Parasitol 89: 241-248. https://doi.org/10.1016/S0304-4017(00)00202-8