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Ramsay Hunt syndrome

  • Jeon, Younghoon (Department of Anesthesiology and Pain Medicine, School of Dentistry, Kyungpook National University) ;
  • Lee, Heryim (Department of Anesthesiology and Pain Medicine, School of Dentistry, Kyungpook National University)
  • Received : 2018.10.31
  • Accepted : 2018.11.30
  • Published : 2018.12.31

Abstract

Ramsay Hunt syndrome is a type of acute herpes zoster, which occurs by reactivation of the varicella-zoster virus at the geniculate ganglion. Clinical presentation of Ramsay Hunt syndrome includes a vesicular rash on the ear (herpes zoster oticus) or in the oral mucosa accompanied by acute peripheral facial nerve paralysis. Other cranial nerves such as V, IX, XI, and XII are often involved. Additional variability of the clinical picture of Ramsay Hunt syndrome is produced by varying patterns of skin involvement explained by individual anastomoses between cranial and cervical nerves. Combination treatment containing anti-viral agents and steroids is recommended for the treatment of Ramsay Hunt syndrome. Additionally, early diagnosis of Ramsay Hunt syndrome is a crucial factor to improve damaged nerves in Ramsay Hunt syndrome, which initiates treatment as soon as possible.

Keywords

References

  1. Jeon YH. Herpes Zoster and Postherpetic Neuralgia: Practical Consideration for Prevention and Treatment. Korean J Pain 2015; 28: 177-84. https://doi.org/10.3344/kjp.2015.28.3.177
  2. Kennedy PG. Varicella-zoster virus latency in human ganglia. Rev Med Virol 2002; 12: 327-34. https://doi.org/10.1002/rmv.362
  3. Chernev I, Dado D. Segmental zoster abdominal paresis (zoster pseudohernia): a review of the literature. PM R 2013; 5: 786-90. https://doi.org/10.1016/j.pmrj.2013.05.013
  4. Kim S, Jeon Y. Treatment of Abdominal Segmental Hernia, Constipation, and Pain Following Herpes Zoster with Paravertebral Block. Pain Physician 2015; 18: E927-E9.
  5. Hunt JR. On herpetic inflammations of the geniculate ganglion: a new syndrome and its complications. J Nerv Ment Dis 1907; 34: 73-96. https://doi.org/10.1097/00005053-190702000-00001
  6. Paul E, Thiel T. Zur Epidemiologie der Varizella-Zoster- Infektion. Hautarzt 1996; 47: 604-9. https://doi.org/10.1007/s001050050476
  7. Nahm FS, Kim SH, Kim HS, Shin JW, Yoo SH, Yoon MH, et al. Survey on the treatment of postherpetic neuralgia in Korea; multicenter study of 1,414 patients. Korean J Pain 2013; 26: 21-6. https://doi.org/10.3344/kjp.2013.26.1.21
  8. Robillard RB, Hilsinger RL Jr, Adour KK. Ramsay Hunt facial paralysis: clinical analyses of 185 patients. Otolaryngol Head Neck Surg 1986; 95: 292-7. https://doi.org/10.1177/01945998860953P105
  9. Hato N, Kisaki H, Honda N, Gyo K, Murakami S, Yanagihara N. Ramsay Hunt syndrome in children. Ann Neurol 2000; 48: 254-6. https://doi.org/10.1002/1531-8249(200008)48:2<254::AID-ANA17>3.0.CO;2-V
  10. Ragozzino MW, Meltan LJ, Kurland LT, Chu CP, Perry HO. Population based study of herpes zoster and its sequelae. Medicine 1982; 61: 310-6. https://doi.org/10.1097/00005792-198209000-00003
  11. Devriese PP, Moesker WH. The natural history of facial paralysis in herpes zoster. Clin Otolaryngol 1988; 13: 289-98. https://doi.org/10.1111/j.1365-2273.1988.tb01134.x
  12. Murakami S, Hato N, Horiuchi J, Honda N, Gyo K, Yanagihara N. Treatment of Ramsay Hunt syndrome with acyclovir-prednisone: Significance of early diagnosis and treatment. Ann Neurol 1997; 41: 353-7. https://doi.org/10.1002/ana.410410310
  13. Sweeney CJ, Gilden DH. Ramsay Hunt syndrome. J Neurol Neurosurg Psychiatry 2001; 71: 149-54. https://doi.org/10.1136/jnnp.71.2.149
  14. Walther LE, Prosowsky K, Walther A, Gudziol H. Untersuchungen zum Zoster oticus. Laryngo-Rhino-Otol 2004; 83: 355-62. https://doi.org/10.1055/s-2004-814105
  15. Wagner G, Klinge H, Sachse MM. Ramsay Hunt syndrome J Dtsch Dermatol Ges 2012; 10: 238-44.
  16. Nanda A, Khan IS. Nervus intermedius and geniculate neuralgia. World Neurosurg 2013; 79: 651-2. https://doi.org/10.1016/j.wneu.2012.05.002
  17. Gupta NM, Parikh MP, Panginikkod S, Gopalakrishnan V. Ramsay Hunt syndrome. QJM 2016; 109: 693. https://doi.org/10.1093/qjmed/hcw113
  18. Murakami S, Hato N, Horiuchi J, Honda N, Gyo K, Yanagihara N. Treatment of Ramsay Hunt syndrome with acyclovir-prednisone: significance of early diagnosis and treatment. Ann Neurol 1997; 41: 353-7. https://doi.org/10.1002/ana.410410310
  19. Xanthopoulos J, Noussios G, Papaioannides D, Exarchakos G, Assimakopoulos D. Ramsay Hunt syndrome presenting as a cranial polyneuropathy. Acta Otorhinolaryngol Belg 2002; 56: 319-23.
  20. Asnis DS, Micic L, Giaccio D. Ramsay Hunt syndrome presenting as a cranial polyneuropathy. Cutis 1996; 57: 421-4.
  21. Cheung MY, Viney M. A unique case of recurrent asystole secondary to paroxysmal pain of acute herpetic ophthalmicus. Anesth Analg 2007; 105: 1127-9. https://doi.org/10.1213/01.ane.0000280536.96489.95
  22. Dayan RR, Peleg R. Herpes zoster - typical and atypical presentations. Postgrad Med 2017; 129: 567-71. https://doi.org/10.1080/00325481.2017.1335574
  23. Sauerbrei A, Eichhorn U, Schacke M, Wutzler P. Laboratory diagnosis of herpes zoster. J Clin Virol 1999; 14: 31e6. https://doi.org/10.1016/S1386-6532(99)00042-6
  24. Terada K, Niizuma T, Kawano S, Kataoka N, Akisada T, Orita Y. Detection of varicellazoster virus DNA in peripheral mononuclear cells from patients with Ramsay Hunt syndrome or zoster sine herpete. J Med Virol 1998; 56: 359-63. https://doi.org/10.1002/(SICI)1096-9071(199812)56:4<359::AID-JMV12>3.0.CO;2-9
  25. Furuta Y, Ohtani F, Mesuda Y, Takasu T, Inuyama Y, Nagashima K. Early diagnosis of zoster sine herpete and antiviral therapy for the treatment of facial palsy. Neurology 2000; 55: 708-10. https://doi.org/10.1212/WNL.55.5.708
  26. Adour KK. Combination treatment with acyclovir and prednisone for Bell palsy. Arch Otolaryngol Head Neck Surg 1998; 124: 824 https://doi.org/10.1001/archotol.124.7.824
  27. Kinishi M, Amatsu M, Mohri M. Acyclovir improves recovery rate of facial nerve palsy in Ramsay Hunt syndrome. Auris Nasus Larynx 2001; 28: 223-6. https://doi.org/10.1016/S0385-8146(01)00055-4

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