Textile Science and Engineering (한국섬유공학회지)

The Korean Fiber Society (한국섬유공학회)
권호 표지
DOI QR코드

DOI QR Code

Amperometric Properties of Immobilized Glucose Oxidase on a Cellulose Nanomembrane Patch Sensor

Glucose oxidase/Cellulose 나노멤브레인을 이용한 Glucose 응답형 Patch 센서의 전기화학적 특성

  • Kim, Kyu Oh (Department of Fiber-system Engineering, Dankook University) ;
  • Kim, Geon Jin (Department of Fiber-system Engineering, Dankook University)
  • 김규오 (단국대학교 파이버시스템공학과) ;
  • 김건진 (단국대학교 파이버시스템공학과)
  • Received : 2018.01.07
  • Accepted : 2018.02.05
  • Published : 2018.02.28
⟨ Previous Next ⟩

Abstract

Highly selective and efficient electrochemical non-invasive epidermal glucose sensors were fabricated using electrospun cellulose-immobilized glucose oxidase (cellulose/GOx) nanofiber membranes. CA nanofiber membranes displayed homogeneous, smooth, and strongly interconnected nanofibers with fiber diameter of $0.21{\pm}0.1{\mu}m$ after treatment with 0.05 NaOH aqueous solution. The electrochemical oxidation of glucose was chosen for the detection of glucose and was achieved through the fabricated nanofiber membranes. Furthermore, the fabricated nanofiber membrane exhibited good selectivity, high stability, and high reproducibility, and hence, it can be used in wearable noninvasive epidermal glucose sensors.

Keywords

References

  1. J. Wang, "Glucose Biosensors: 40 Years of Advances and Challenges", Electroanalysis, 2001, 13, 983-988. https://doi.org/10.1002/1521-4109(200108)13:12<983::AID-ELAN983>3.0.CO;2-#
  2. P. Glikfeld, R. S. Hinz, and R. H. Guy, "Noninvasive Sampling of Biological Fluids by Iontophoresis", Pharm. Res., 1989, 6, 988-990. https://doi.org/10.1023/A:1015957816254
  3. G. Rao, P. Glikfeld, and R. H. Guy, "Reverse Iontophoresis: Development of a Noninvasive Approach for Glucose Monitoring", Pharm. Res., 1993, 10, 1751-1755. https://doi.org/10.1023/A:1018926215306
  4. M. S. Norn, "Tear Fluid pH in Normals, Contact Lens Wearers, and Pathological Case", Acta Ophthalmol., 1988, 66, 485-489.
  5. D. H. Conrad, J. Goyette, and P. S. Thomas, "Proteomics as a Method for Early Detection of Cancer: A Review of Proteomics, Exhaled Breath Condensate, and Lung Cancer Screening", J. Gen. Intern. Med., 2008, 23, 78-84. https://doi.org/10.1007/s11606-007-0411-1
  6. P. Glikfeld, R. S. Hinz, and R. H. Guy, "Noninvasive Sampling of Biological Fluids by Iontophoresis", Pharm Res., 1989, 6, 988-990. https://doi.org/10.1023/A:1015957816254
  7. Y. Luo, S. Nartker, H. Miller, D. Hochhalter, M. Wiederoder, S. Wiederoder, E. Setterington, L. T. Drzal, and E. C. Alocilja, "Surface Functionalization of Electrospun Nanofibers for Detecting E. coli O157:H7 and BVDV Cells in a Direct-charge Transfer Biosensor", Biosens. Bioelectron, 2010, 26, 1612-1617. https://doi.org/10.1016/j.bios.2010.08.028
  8. E. Spain, R. Kojima, R. B. Kaner, G. G. Wallace, J. O'Grady, K. Lacey, T. Barry, T. E. Keyes, and R. J. Forster, "High Sensitivity DNA Detection Using Gold Nanoparticle Functionalised Polyaniline Nanofibres", Biosens. Bioelectron., 2011, 26, 2613- 2618. https://doi.org/10.1016/j.bios.2010.11.017
  9. H. Liu and Y. Hsieh, "Ultrafine Fibrous Cellulose Membranes from Electrospinning of Cellulose Acetate", Inc. J. Polym. Sci., Part B: Polym. Phys., 2002, 40, 2119-2129. https://doi.org/10.1002/polb.10261
  10. W. K. Son, J. H. Youk, T. S. Lee, and W. H. Park, "Electrospinning of Ultrafine Cellulose Acetate Fibers: Studies of a New Solvent System and Deacetylation of Ultrafine Cellulose Acetate Fibers", J. Polym. Sci. Part B: Polym. Phys., 2004, 42, 5-11. https://doi.org/10.1002/polb.10668
  11. Z. Ma, M. Kotaki, and S. Ramakrishna, "Electrospun Cellulose Nanofiber as Affinity Membrane", J. Membr. Sci., 2005, 265, 115-123. https://doi.org/10.1016/j.memsci.2005.04.044
  12. S. Rauf, A. Ihsan, K. Akhtar, M. A. Ghauri, M. Rahman, M. A. Anwar, and A. M. Khalid, "Glucose Oxidase Immobilization on a Novel Cellulose Acetate-polymethylmethacrylate Membrane", J. Biotec., 2006, 121, 351-360. https://doi.org/10.1016/j.jbiotec.2005.08.019
  13. K. O. Kim and B. S. Kim, "Immobilization of Glucose Oxidase on a PVA/PAA Nanofiber Matrix Reduces the Effect of the Hematocrit Levels on a Glucose Biosensor", J. Fiber Sci. Technol., 2017, 73, 27-33. https://doi.org/10.2115/fiberst.fiberst.2017-0004
  14. M. Tierney, J. Tamada, R. Potts, L. Jovanovic, and S. Garg, "Clinical Evaluation of the Glucowatch Biographer: a Continual, Non-invasive Glucose Monitor for Patients with Diabetes", Biosens. Bioelectron., 2001, 16, 621-629. https://doi.org/10.1016/S0956-5663(01)00189-0