The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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A Case Report of Suggested Liver Dysfunction by Atorvastatin Treated with Saenggangeonbi-tang

Atorvastatin이 주요 원인으로 추정되는 간 기능 장애에 대한 생간건비탕 가미방 치험 1례

  • Kwon, Jung-yeon (Dept. of Korean Internal Medicine, College of Korean Medicine, Se-Myung University) ;
  • Kim, Young-ji (Dept. of Korean Internal Medicine, College of Korean Medicine, Se-Myung University) ;
  • Park, Jang-kyung (National Development Institute of Korean Medicine) ;
  • Kong, Kyung-hwan (Dept. of Korean Internal Medicine, College of Korean Medicine, Se-Myung University) ;
  • Go, Ho-yeon (Dept. of Korean Internal Medicine, College of Korean Medicine, Se-Myung University)
  • 권정연 (세명대학교 한의과대학 한방내과학교실) ;
  • 김영지 (세명대학교 한의과대학 한방내과학교실) ;
  • 박장경 (한약진흥재단) ;
  • 공경환 (세명대학교 한의과대학 한방내과학교실) ;
  • 고호연 (세명대학교 한의과대학 한방내과학교실)
  • Received : 2017.09.11
  • Accepted : 2017.10.27
  • Published : 2017.10.30
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Abstract

Objective: A general prejudice exists that all herbal medicines are not good for liver. We report that herbal medicine can have positive effects on the liver, based on the improved liver function test levels observed in one patient. We also suggest the effectiveness of co-administration of herbal and western medicines. Methods: We checked the liver function test levels of one patient measured on 12 July at another hospital. We identified worse levels on 7 August, when he was first admitted to Semyung University Hospital. We measured liver function test levels of the same patient after treatment with Korean herbal medicine on 14 and 21 August during hospitalization at Semyung Hospital. We compared the figures and evaluated the effectiveness of 'Saenggangeonbi-tang' herbal medicine in the liver. Results: The patient's liver function test levels were normal on 12 July, but had become abnormal by 7 August, when he was admitted to Semyung Hospital. The cause of liver dysfunction was suggested as Atorvastatin, one of the western drugs he had started to take. Continuous treatment with Korean herbal medicine resulted in a definite improvement in liver function. Conclusion: Korean herbal medicine can provide positive improvements in liver function test levels.

Keywords

References

  1. Yang JH, Lee JY, Kim KS, Jeong YJ, Kim HK, Lee EJ, et al. One Case of Report of Acute Cholestatic-Hepatitis(Drug Induced Hepatits) After Taking Herbal-Medicine. Korean J Orient Int Med 2011;22(2):251-56.
  2. Lee BR, Kim WI. A Case Report of the Effect of Korean Medicine on Liver Function Test of Drug-Induced Liver Injury Patient Treated with Western Medicine. Herbal Formula Science (HFS) 2014;22(1):193-200. https://doi.org/10.14374/HFS.2014.22.1.193
  3. Seo JY, Kim JR, Yoo BW. Interpretation of Liver Function Test. Korean J Fam Pract 2012;2:207-13.
  4. Ahn SY, Park SY. A Diagnostic Approach to Abnormal Liver Function Tests in Asymptomatic Patients. The Korean journal of internal medicine 2012;82(2):134-42.
  5. Chun WJ, Yoon BG, Kim NI, Lee Goo, Yang CH, Lee CH, et al. A Clinical Study of Patients with Acute Liver Injury Caused by Herbal Medication in Gyeongu area. Korea J medicine 2002;63(2):141-50.
  6. Kim DM, Kim HK, Cho SY, Kim YS, Nam SS. Retrospective Observation of Liver Function Parameters for 101 Patients Using Herbal Drugs for One Month. J Korean Oriental Med 2010;31(2):149-57.
  7. Yang JH, Lee JY, Kim KW, Jeong YJ, Kim HK, Lee EJ, et al. One Case of Report of Acute Cholestatic-Hepatitis(Drug Induced Hepatits) After Taking Herbal-Medicine. Korean J Orient Int Med 2001;22(2):251-6.
  8. Lee SN, Kim SJ, Lee JS, Kim EG, Jang SG. Effect of Ganjeonggyeok Acupuncture and Saengkankunbi-tang Treatment in the Changes of LFT and Lipid-obesity Index Values. The Journal of Korean Acupuncture & Moxibustion Society 2008;25(6):47-54.
  9. Kim KA. Understanding and application of liver function tests. The Korean journal of internal medicine 2009;76(2):163-8.
  10. Korean society for laboratory medicine. Laboratory Medicine. 5th edition. Seoul: Bummoon Education; 2017, p. 406-11.
  11. Yu DJ, Choi US, Kang SB. Case Study of Liver Function Recovery by Oriental Medicine in Traffic Accident Patient. The Jornal of East-West Medicine 2010;35(3):51-6.
  12. Baik JW, Hsia YC, Park JH, Jun CY, Choi YK. A Case of Drug-Induced Liver Injury Treated with Saenggangeonbi-tang in the Treatment of Western Medicine for Cerebral Infarction. The Journal of Kyungwon University Oriental Medicine laboratory 2009;13:21-32.
  13. Druginfo. https://www.druginfo.co.kr/detail/product.aspx?pid=203875
  14. Druginfo. https://www.druginfo.co.kr/detail/product.aspx?pid=45978
  15. Druginfo. https://www.druginfo.co.kr/detail/product.aspx?pid=40694
  16. Seo YH, Kim JD, Choi HY, Jung TY. Case Report of Suggested Alcoholic Hepatitis Treated with Saenggangeonbi-tang and Kongjin-Dan. The Journal of East-West Medicine 2011;36(4):83-9.
  17. Shin YS, Cho SH, Kim NU, Han YH. Clinical Report of Acute Cholecystitis with Gagamsaenggantang. Korean J Oriental Physiology & Pathology 2009;23(6):1465-9.

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