Journal of the Korea Academia-Industrial cooperation Society (한국산학기술학회논문지)

The Korea Academia-Industrial cooperation Society (한국산학기술학회)
권호 표지
DOI QR코드

DOI QR Code

Relationships Between Drinking Patterns and Metabolic Syndrome Among Korean Adolescents: Analysis of the Sixth(2013-2015) Korea National Health and Nutrition Examination Survey

한국 청소년의 음주행태와 대사증후군과의 관련성: 제6기(2013-2015년) 국민건강영양조사 자료 분석

  • Received : 2017.08.21
  • Accepted : 2017.09.15
  • Published : 2017.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

This study was conducted to examine relationships between drinking patterns and metabolic syndrome among Korean adolescents. Statistically weighted data from the Sixth(2013-2015) Korea National Health and Nutrition Examination Survey data were analyzed. Multivariate logistic regression was used to determine relationships between adolescent drinking patterns and metabolic syndrome risk factors with adjustments for individual covariates. A total of 1,698 Korean adolescents (Men=901, Women=797) were identified. Among male adolescents, drinking frequency in the past year was significantly associated with triglyceride level (p for trend=0.03); and men who usually consumed ${\geq}5$ drinks on a typical occasion had a greater risk of high-triglyceride level (adjusted odds ratios: 2.72, 95% confidence intervals: 1.00-7.34, p=0.05). Among female adolescents, drinking frequency in the past year was significantly associated with blood high-density lipoprotein cholesterol level(p for trend=0.01). Drinking frequency and amount were associated with higher triglyceride level among male adolescents, indicating that adolescent drinking may be associated with increased metabolic syndrome development in adulthood. The study results suggest that continuous drinking prevention education and further research for adolescents and metabolic syndrome predictors are needed to prevent development of metabolic syndrome in adulthood.

본 연구는 제6기(2013-2015년) 국민건강영양조사 자료를 이용하여 만12세 이상 19세 미만 청소년의 음주행태와 대사증후군의 관련성을 파악하고자 시도되었다. 청소년의 음주행태와 대사증후군 위험요인들과의 상관관계를 확인하기 위해 Multivariate logistic regression을 이용하여 분석하였다. 대상자는 총 1,698명으로 남자 901명, 여자 797명이었다. 남자 청소년의 경우 최근 1년간 음주빈도와 혈중 중성지방에 유의한 상관관계가 나타났다(p for trend=0.03). 한 번에 마시는 음주량이 5잔 이상일 경우 고중성지방혈증이 나타날 위험성이 유의하게 높아지는 것으로 나타났다(OR 2.28, 95% CI 1.12-4.66, p=0.02). 여자 청소년에서 최근 1년간 음주빈도와 혈중 고밀도지단백 콜레스테롤 수치 사이에 유의한 상관관계가 나타났다(p for trend=0.01). 남자 청소년에서 음주빈도와 음주량이 대사증후군의 위험인자인 혈중 중성지방 증가와 관련성이 나타났다. 이는 청소년 음주가 성인기의 대사증후군으로 발전 가능성이 높음을 시사한다. 본 연구결과를 근거로 청소년기의 음주가 성인기의 대사증후군으로 발전 되는 것을 예방하기 위해 지속적인 음주예방교육과 음주와 성인기 대사증후군 예측요인 간의 보다 엄밀한 연구를 제언한다.

Keywords

References

  1. Lim, S. S., Vos, T., Flaxman, A. D., Danaei, G., Shibuya, K., Adair-Rohani, H., et al, "A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990?2010: a systematic analysis for the Global Burden of Disease Study 2010", The lancet, vol. 380, no. 9859, pp. 2224-2260, 2012. DOI: https://10.1016/S0140-6736(12)61766-8
  2. World Health Organization(WHO), "Global status report on alcohol and health", 2014. Available from: http://www.who.int/substance_abuse/publications/alcohol_2014/en/ (accessed Aug., 18, 2017)
  3. Gunn, R. L., Smith, G. T., "Risk factors for elementary school drinking: Pubertal status, personality, and alcohol expectancies concurrently predict fifth grade alcohol consumption", Psychology of Addictive Behaviors, vol. 24, no. 4, pp. 617-627, 2010. DOI: https://10.1037/a0020334
  4. National Institute on Alcohol Abuse and Alcoholism (NIAAA). Alcohol Alert, No. 67, "Underage Drinking," 2006. Available from: https://pubs.niaaa.nih.gov/publications/AA67/AA67.htm. (accessed Aug., 18, 2017)
  5. McCambridge, J., McAlaney, J., Rowe, R., "Adult Consequences of Late Adolescent Alcohol Consumption: A Systematic Review of Cohort Studies", PLoS Medicine, vol. 8, no. 2, e1000413, 2011. DOI: http://doi.org/10.1371/journal.pmed.1000413
  6. National Institute on Alcohol Abuse and Alcoholism (NIAAA). 2016. Available from: https://pubs.niaaa.nih.gov/publications/underagedrinking/underagefact.htm (accessed Aug., 18, 2017)
  7. Kim, J., Chung, W., Lee, S., Park, C., "Estimating the socioeconomic costs of alcohol drinking among adolescents in Korea", Journal of Preventive Medicine and Public Health=Yebang Uihakhoe chi, vol. 43, no. 4, pp. 341-351, 2010. https://doi.org/10.3961/jpmph.2010.43.4.341
  8. Ministry of Education, Ministry of Health and Welfare, & Korea Centers for Disease Control. Statistics of the 12th(2016) Korea Youth Risk Behavior Web-based Survey. Seoul: Korea Centers for Disease Control.
  9. Reaven, G.M, "Role of insulin resistance in human disease", Diabetes, vol. 37, no. 12, pp. 1595-1607, 1988. DOI: https://doi.org/10.2337/diabetes.37.12.1595
  10. Klein, B.E., Klein, R., Lee, K.E., "Components of the metabolic syndrome and risk of cardiovascular disease and diabetes in Beaver Dam", Diabetes Care, vol. 25, no. 10, pp. 1790-1794, 2002. DOI: https://doi.org/10.2337/diacare.25.10.1790
  11. Baik, I., Shin, C., "Prospective study of alcohol consumption and metabolic syndrome", The American Journal of Clinical Nutrition, vol. 87, no. 5, pp. 1455-1463, 2008. https://doi.org/10.1093/ajcn/87.5.1455
  12. Lee, K. W., Park, B. J., Kang, H. T., Lee, Y. J., "Alcohol-drinking patterns and metabolic syndrome risk: the 2007 Korean National Health and Nutrition Examination Survey", Alcohol, vol. 45, no. 5, pp. 499-505, 2011. DOI: https://10.1016/j.alcohol.2011.01.001
  13. Lee, K, "Gender-specific relationships between alcohol drinking patterns and metabolic syndrome: the Korea National Health and Nutrition Examination Survey 2008", Public Health Nutrition, vol. 15, no. 10, pp. 1917-1924, 2012. DOI: https://10.1017./S136898001100365X
  14. Yoon, Y. S., Oh, S. W., Baik, H. W., Park, H. S, Kim, W. Y., "Alcohol consumption and the metabolic syndrome in Korean adults: the 1998 Korean National Health and Nutrition Examination Survey", The American Journal of Clinical Nutrition, vol. 80, no. 1, pp. 217-224, 2004. https://doi.org/10.1093/ajcn/80.1.217
  15. Cho, K. O., "Association of body shape index and body mass index with metabolic syndrome risk factors in Korean adolescents: The fifth Korea National Health and Nutrition Survey", Exercise Science, vol. 23, no. 1, pp. 33-40, 2014. DOI: https://doi.org/10.15857/ksep.2014.23.1.33
  16. Hong, Y. M., Song, Y. Y., Kim, H. S., Park, H. S., Min, J. H., Jung, J. W, et al, "Metabolic syndrome in the overweight and obese adolescents and the impact of obesity on the cardiovascular system", Korean Journal of Pediatrics, vol. 52, no. 10, pp. 1109-1118, 2009. DOI: https://10.3345/kjp.2009.52.10.1109
  17. Chen, W., Srinivasan, S. R., Li, S., Xu, J., Berenson, G. S., "Clustering of long-term trends in metabolic syndrome variables from childhood to adulthood in Blacks and Whites: the Bogalusa Heart Study", American Journal of Epidemiology, vol. 166, no. 5, pp. 527-533, 2007. DOI: https://doi.org/10.1093/aje/kwm105
  18. Mattsson, N., Ronnemaa, T., Juonala, M., Viikari, J. S., Raitakari, O. T., "Childhood predictors of the metabolic syndrome in adulthood. The Cardiovascular Risk in Young Finns Study", Annals of Medicine, vol. 40, no. 7, pp. 542-552, 2008. DOI: http://dx.doi.org/10.1080/07853890802307709
  19. McGill, H. C., McMahan, C. A., Herderick, E. E., Zieske, A. W., Malcom, G. T., Tracy, R. E., Strong, J. P., "Obesity accelerates the progression of coronary atherosclerosis in young men", Circulation, vol. 105, no. 23, pp. 2712-2718, 2002. DOI: https://10.1161/01.CIR.0000018121.67607.CE
  20. Ministry of Health and Welfare & Korea Centers for Disease Control. User's guideline of the sixth Korea National Health and Nutrition Survey. Seoul: Korea Centers for Disease Control, 2017.
  21. Cook, S., Weitzman, M., Auinger, P., Nguyen, M., Dietz, W. H., "Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994", Archives of Pediatrics & Adolescent Medicine, vol. 157, no. 8, pp. 821-827, 2003. DOI: https://doi.org/10.1001/archpedi.157.8.821
  22. Korea Center for Disease Control and Prevention, The Korean Pediatric Society. 2007 Korean Children and Adolescents Growth Standard. Available from http://www.cdc.go.kr/CDC/notice/CdcKrInfo0201.jsp?menuIds=HOME001-MNU1154-MNU0005-MNU1889&cid=1235 (accessed Aug., 18, 2017)
  23. White, A., Castle, I.-J. P., Chen, C. M., Shirley, M., Roach, D., & Hingson, R. "Converging Patterns of Alcohol Use and Related Outcomes Among Females and Males in the United States, 2002 to 2012", Alcoholism, Clinical and Experimental Research, vol. 39, no. 9, pp. 1712?1726, 2015. DOI: https://doi.org/10.1111/acer.12815
  24. Piano, M. R., Mazzuco, A., Kang, M., & Phillips, S. A. (2017). Binge Drinking Episodes in Young Adults: How Should We Measure Them in a Research Setting?. Journal of Studies on Alcohol and Drugs, vol. 78, no. 4, pp. 502-511, 2017. DOI: https://doi.org/10.15288/jsad.2017.78.502
  25. Carbia, C., Cadaveira, F., Caama-o-Isorna, F., Rodriguez-Holguin, S., & Corral, M. "Binge drinking during adolescence and young adulthood is associated with deficits in verbal episodic memory", PLOS ONE, vol. 12, no. 2, e0171393, 2017. DOI: https://doi.org/10.1371/journal.pone.0171393
  26. Squeglia, L. M., Tapert, S. F., Sullivan, E. V., Jacobus, J., Meloy, M. J., Rohlfing, T., & Pfefferbaum, A. "Brain development in heavy-drinking adolescents", American Journal of Psychiatry, vol. 172, no. 6, pp. 531?542, 2015. DOI: https://10.1176/appi.ajp.2015.14101249
  27. Tapia-Rojas, C., Carvajal, F. J., Mira, R. G., Arce, C., Lerma-Cabrera, J. M., Orellana, J. A., ... Quintanilla, R. A. "Adolescent binge alcohol exposure affects the brain function through mitochondrial impairment", Molecular Neurobiology, pp. 1?19, 2017. DOI: https://10.1007/s12035-017-0613-4
  28. Seo, S. J., Lee, H. Y., & Lee, S. W. "The Prevalence of the Metabolic Syndrome in Korean Children and Adolescents: Comparisons of the Criteria of Cook et al., Cruz and Goran, and Ferranti et al.", Yonsei medical journal, vol. 49, no. 4, pp. 563-572, 2008. DOI: https://doi.org/10.3349/ymj.2008.49.4.563
  29. Garoufi, A., Grammatikos, E. E., Kollias, A., Grammatikos, E., Stergiou, G. S., & Soldatou, A. "Associations between obesity, adverse behavioral patterns and cardiovascular risk factors among adolescent inhabitants of a Greek island", Journal of Pediatric Endocrinology and Metabolism, vol. 30, no. 4, pp. 445-454, 2017. DOI: https://doi.org/10.1515/jpem-2016-0134
  30. Brien, S. E., Ronksley, P. E., Turner, B. J., Mukamal, K. J., & Ghali, W. A. "Effect of alcohol consumption on biological markers associated with risk of coronary heart disease: systematic review and meta-analysis of interventional studies", Bmj, 342, d636, 2011. DOI: https://doi.org/10.1136/bmj.d636
  31. Wang, X., Magkos, F., & Mittendorfer, B. "Sex differences in lipid and lipoprotein metabolism: it's not just about sex hormones", The Journal of Clinical Endocrinology & Metabolism, vol. 96, no. 4, pp. 885-893, 2011. DOI: https://doi.org/10.1210/jc.2010-2061
  32. Baek, S. I., & So, W. Y. "Relationship between obesity in Korean adolescents and the frequency of alcohol consumption, the amount of alcohol consumed, and the frequency of severe alcohol intoxication", Obesity research & clinical practice, vol. 6, no. 2, pp. e159-e166, 2012. DOI: https://doi.org/10.1016/j.orcp.2011.08.001
  33. Abbs, E. S., Vi-oles, J., Alarcon, J. O., Johnson, H. M., & Zunt, J. R. "High prevalence of cardiovascular risk factors in Peruvian adolescents living in a peri-urban shantytown: a cross-sectional study", Journal of Health, Population and Nutrition, vol. 36, no. 1, 19, 2017. DOI: https://doi.org/10.1186/s41043-017-0093-1
  34. Franklin, S. S., & Wong, N. D. "Hypertension and cardiovascular disease: contributions of the Framingham Heart Study", Global heart, vol. 8, no. 1, pp. 49-57, 2013. DOI: https://doi.org/10.1016/j.gheart.2012.12.004
  35. Al-khalifa, I. I., Mohammed, S. M., & Ali, Z. M. "Cigarette Smoking as a Relative Risk Factor for Metabolic Syndrome", Journal of Endocrinology and Metabolism, vol. 6, no. 6, pp. 178-182, 2017. DOI: https://doi.org/10.14740/jem390e
  36. De Oliveira, R. G., & Guedes, D. P. "Physical Activity, Sedentary Behavior, Cardiorespiratory Fitness and Metabolic Syndrome in Adolescents: Systematic Review and Meta-Analysis of Observational Evidence", PLoS ONE, vol. 11, no. 12, e0168503, 2016. DOI: http://doi.org/10.1371/journal.pone.0168503