Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • 제43권4호
  • /
  • Pages.272-275
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  • 2017
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  • 2234-7550(pISSN)
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  • 2234-5930(eISSN)
대한구강악안면외과학회 (The Korean Association of Oral and Maxillofacial Surgeons)
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A case of bisphosphonate-related osteonecrosis of the jaw with a particularly unfavourable course: a case report

  • Viviano, Massimo (Department of Medical Biotechnologies, Dentistry Clinic) ;
  • Addamo, Alessandra (Department of Medical Biotechnologies, Dentistry Clinic) ;
  • Cocca, Serena (Department of Medicine, Surgery and Neurosciences, ENT Clinic, University of Siena)
  • 투고 : 2016.09.05
  • 심사 : 2016.11.10
  • 발행 : 2017.08.31
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초록

Bisphosphonates are drugs used to treat osteoclast-mediated bone resorption, including osteoporosis, Paget disease, multiple myeloma, cancer-related osteolysis, and malignant hypercalcemia. The use of these drugs has increased in recent years as have their complications, especially bisphosphonate-related osteonecrosis of the jaw (BRONJ), which more frequently affects the mandible. Here we report a case of BRONJ with a particularly unfavorable course due to cervical inflammation that developed into necrotizing fasciitis, followed by multiorgan involvement leading to septic shock and death.

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참고문헌

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피인용 문헌

  1. Necrotizing fasciitis as a complication of osteonecrosis of the jaw related to oral bisphosphonate application in a patient with osteoporosis: a case report vol.23, pp.1, 2019, https://doi.org/10.1007/s10006-018-0725-7
  2. Evaluation of the qualitative and quantitative composition of or al microbiota in patients with medial osteonecrosis of the jaw vol.2019, pp.2, 2017, https://doi.org/10.36233/0372-9311-2019-2-82-86
  3. A critical assessment of the medication-related osteonecrosis of the jaw classification in stage I patients: a retrospective analysis vol.47, pp.2, 2017, https://doi.org/10.5125/jkaoms.2021.47.2.99