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Characteristics of antimicrobial resistant Salmonella Typhimurium isolates from pigs

돼지에서 분리한 Salmonella Typhimurium의 항생제 내성 양상

  • Sohn, Jun Hyung (North Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Kim, Mee Suk (North Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Lee, Young Mi (North Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Do, Jae Cheul (East Branch, Gyeongbuk Veterinary Service Laboratory)
  • 손준형 (경북동물위생시험소 북부지소) ;
  • 김미숙 (경북동물위생시험소 북부지소) ;
  • 이영미 (경북동물위생시험소 북부지소) ;
  • 도재철 (경북동물위생시험소 동부지소)
  • Received : 2017.01.25
  • Accepted : 2017.06.21
  • Published : 2017.06.30

Abstract

59 strains of Salmonella enterica subspecies enterica serovar Typhimurium (S. Typhimurium) were isolated from pigs in Gyeongbuk province, collected from 2011 to 2016. The isolates were investigated for the presence of antimicrobial resistance and multi drug resistance patterns. All 59 S. Typhimurium isolates were resistant to at least one of 10 antibiotics used in this study, 100% of S. Typhimurium isolates from pigs were resistant to two or more antimicrobials. As many as 5 isolates of isolates from pigs were resistant to 8 of 10 antimicrobials tested in this study. The ACSTNaGmKNaCf, ACSTGmAuKT/S, ACSTGmKCfT/S resistance phenotype was observed in 3.4%, 3.4%, 1.7% of the 59 isolates, respectively.

Keywords

References

  1. Araque M. 2009. Nontyphoid Salmonella gastroenteritis in pediatric patients from urban areas in the city of Merida, Venezuela. J Infect Dev Ctries 3: 28-34.
  2. Baggesen DL, Sandvang D, Aarestrup FM. 2000. Charaterization of Salmonella enterica serovar Typhimurium DT104 isolated from Denmark and comparison with isolates from Europe and the United States. J Clin Mirobiol 38: 1581-1586.
  3. Benenson AS, Chin J, Benenson AS, Chin J. 1995. Control of communicable diseases manual. American Public Health Association, Washington DC.
  4. Chen S, Zhao S, White DG, Schroeder CM, Lu R, Yang H, McDermott PF, Ayers S, Meng J. 2004. Characterization of multiple-antimicrobial-resistant Salmonella serovars isolated from retail meats. J Appl Environ Microbiol 70: 1-7. https://doi.org/10.1128/AEM.70.1.1-7.2004
  5. Cho JK, Kang MS, Kim KS. 2011. Serotypes, antimicrobial resistance of Salmonella spp. and plasmid profiles, phage types, PFGE of S. Enteritidis and S. Typhimurium isolated from ducks in Daegu-Gyeongbuk province. Korean J Vet Serv 34: 217-226. https://doi.org/10.7853/kjvs.2011.34.3.217
  6. Clinical and Laboratory Standards Institute (CLSI). 2012. Performance standards for antimicrobial susceptibility testing; twenty-second informational supplements (M100-S22). CLSI, Wayne, Pa.
  7. Davis MA, Besser TE, Eckmann K, MacDonald K, Green D, Hancock DD, Baker KN, Warnick LD, Soyer Y, Wiedmann M, Call DR. 2007. Multidrug-resistant Salmonella typhimurium, Pacific Northwest, United States. Emerg Infect Dis 13: 1583-1586. https://doi.org/10.3201/eid1310.070536
  8. Funk J, Gebreyes WA. 2004. Risk factors associated with Salmonella prevalence on swine farms. J Swine Health Prod 12: 246-251.
  9. Futagawa-Saito K, Hiratsuka S, Kamibeppu M, Hirosawa T, Oyabu K, Fukuyasu T. 2008. Salmonella in healthy pigs: Prevalence, serotype diversity and antimicrobial resistance observed during 1998-1999 and 2004-2005 in Japan. Epidemiol Infect 136: 1118-1123.
  10. Graziani C, Busani L, Dionisi AM, Lucarelli C, Owczarek S, Ricci A, Mancin M, Caprioli A, Luzzi I. 2008. Antimicrobial resistance in Salmonella enterica serovar Typhimurium from human and animal sources in Italy. Vet Microbiol 128: 414-418. https://doi.org/10.1016/j.vetmic.2007.10.017
  11. Guerra B, Schrörs P, Mendoza MC. 2000. Application of PFGE performed with XbaI to an epidemiological and phylogenetic study of Salmonella serotype typhimurium. Relations between genetic types and phage types. New Microbiol 23: 11-20.
  12. Kim KT, Kim WI, Kim SY, Jang YS, Kim DW, Kim BH. 2000. Antibiotic resistance and plasmid profile of Salmonella spp isolated from swine in Kyoungbuk province. Korean J Vet Serv 23: 77-91.
  13. Lee KE, Lee Y. 2007. Isolation of multidrug-resistant Salmonella typhimurium DT104 from swine in Korea. J Microbiol 45: 590-592.
  14. Martinez JL, Baquero F. 2002. Interactions among strategies associated with bacterial infection: Pathogenicity, epidemicity, and antibiotic resistance. Clin Microbiol Rev 15: 647-679. https://doi.org/10.1128/CMR.15.4.647-679.2002
  15. Moon JY, Kim WK, Lee KH, Na BJ, Go JC, Sim KS, Patil TA, Hur J. 2016. Characteristics of antimicrobial resistant Salmonella Typhimurium isolates from chicken and pigs. Korean J Vet Serv 39: 51-57. https://doi.org/10.7853/kjvs.2016.39.1.51
  16. Nielsen EM, Torpdahl M, Ethelberg S, Hammerum AM. 2009. Variation in Antimicrobial resistance in sporadic and outbreak-related Salmonella enterica serovar Typhimurium. Emerg Infect Dis 15: 101-103. https://doi.org/10.3201/eid1501.080853
  17. Poppe C, Kolar JJ, Demczuk WH, Harris JE. 1995. Drug resistance and biochemical characteristics of Salmonella from turkeys. Can J Vet Res 59: 241-248.
  18. Oh YH, Lee YG, Jung YT, Lee H, Kim AK, Kim DI, Park SK, Kim MH. 2004. Molecular Characterization of Multidrug Resistant Salmonella enterica serovar Typhimurium Clinical Isolates in Seoul. Konkuk univ Press. Seoul.
  19. Olsen SJ, DeBess EE, McGivern TE, Marano N, Eby T, Mauvais S, Balan VK, Zirnstein G, Cieslak PR, Angulo FJ. 2001. A nosocomial outbreak of fluoroquinolone-resistant Salmonella infection. N Engl J Med 344: 1572-1579. https://doi.org/10.1056/NEJM200105243442102
  20. Shahada F, Amamoto A, Chuma T, Shirai A, Okamoto K. 2007. Antimicrobial susceptibility phenotypes, resistance determinants and DNA fingerprints of Salmonella enterica serotype Typhimurium isolated from bovine in Southern Japan. Int J Antimicrob Agents 30: 150-156. https://doi.org/10.1016/j.ijantimicag.2007.03.017
  21. Smith P. 2008. Aquaculture and florfenicol resistance in Salmonella enterica Typhimurium DT104. Emerg Infect Dis 14: 1327-1328.
  22. Steven AC, Alison EB, Ronald WG. 2012. Salmonellosis. pp. 821-833. In: Jeffrey J. Zimmerman, Locke A, Karriker, Alejandro Ramirez, Kent J. Schwartz, Gregory W. Stevenson (ed.). Disease of Swine. 10th ed. A John Wiley & Sons. Ames, Iowa.
  23. Tauxe RV. 1991. Salmonella: A postmodern pathogen. J Food Prot 54: 563-568. https://doi.org/10.4315/0362-028X-54.7.563
  24. Threlfall EJ, Rowe B, Ward LR. 1993. A comparison of multiple drug resistance in salmonellas from humans and food animals in England and Wales, 1981 and 1990. Epidemiol Infect 111: 189-197. https://doi.org/10.1017/S0950268800056892
  25. Yoo AN, Cha SB, Shin MK, Won HK, Kim EH, Choi HW, Yoo HS. 2014. Serotypre and antimicrobial resistance patterns of the recent Korean Actinobacillus pleuropneumoniae isolates. Vet Rec 174: 223. https://doi.org/10.1136/vr.101863