Imaging Science in Dentistry

Korean Academy of Oral and Maxillofacial Radiology (대한영상치의학회)
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Squamous cell carcinoma arising within a maxillary odontogenic keratocyst: A rare occurrence

  • Jalali, Elnaz (Eliray Oral and Maxillofacial Radiology Consulting Services) ;
  • Ferneini, Elie M. (Department of Craniofacial Sciences, Division of Oral and Maxillofacial Surgery, University of Connecticut, School of Dental Medicine) ;
  • Rengasamy, Kandasamy (Section of Oral and Maxillofacial Radiology, University of Connecticut, School of Dental Medicine) ;
  • Tadinada, Aditya (Section of Oral and Maxillofacial Radiology, University of Connecticut, School of Dental Medicine)
  • Received : 2017.02.10
  • Accepted : 2017.03.24
  • Published : 2017.06.30
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Abstract

Squamous cell carcinoma (SCC) arising within the lining of an odontogenic keratocyst (OKC) is a rare occurrence. Although potentially locally destructive, OKC is a benign odontogenic process that typically presents with clinical and radiographic features characteristic of a benign intraosseous neoplasm. We present the clinical and radiographic features of a maxillary mass that demonstrated SCC arising from the lining of an OKC. Although the initial clinical and radiographic presentation suggested an infection or malignant neoplasm, biopsies revealed an infiltrative well-differentiated SCC contiguous with and arising from the focus of a pre-existing OKC. The patient subsequently underwent a type II hemi-maxillectomy with neoadjuvant chemoradiation. This report discusses the clinical and radiographic features associated with intraosseous malignancies, especially those arising from an otherwise benign odontogenic lesion. While the majority of OKCs are benign, the current report illustrates the potential for carcinomatous transformation within the lining of an OKC.

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References

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