Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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Adjuvant medications to local anesthetics in nerve blockade

신경차단 시 국소마취제와 함께 사용되는 보조 약물들

  • Lee, Deok Hee (Department of Anesthesiology and Pain Medicine, Yeungnam University College of Medicine)
  • 이덕희 (영남대학교 의과대학 마취통증의학교실)
  • Received : 2017.04.30
  • Accepted : 2017.07.27
  • Published : 2017.12.31
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Abstract

Peripheral nerve blocks are commonly used for surgical anesthesia, postoperative analgesia, and to reduce opioid requirements. Although these blocks have traditionally been carried out using local anesthetics, single-injection techniques can be short-lived and limited by the relatively brief duration of action of currently available local anesthetics. Increasing the dose or concentration of local anesthetics may prolong the duration of analgesia, but may also increase the risk such as unwanted motor weakness or systemic toxicity of local anesthetics. Numerous adjuvant medications have been added to local anesthetics to prolong the durations of anesthesia and analgesia achieved by peripheral nerve blocks, and currently, a number of different adjuvants are used to improve quality of the block. This article will review the several nerve block adjuvants used in combination with local anesthetics to provide blockade of peripheral nerves in clinical practice, describing the rationale for their use in peripheral nerve blocks, and the evidence for their effectiveness.

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References

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