Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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A case of Langerhans cell histiocytosis involving the cervical lymph node

경부 임파선을 침범한 랑게르한스 세포 조직구증 1예

  • Seo, Youn Tae (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu) ;
  • Son, Ho Jin (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu) ;
  • Jang, Gyu Ho (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu) ;
  • Kim, Jeong Kyu (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu)
  • 서윤태 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 손호진 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 장규호 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 김정규 (대구가톨릭대학교 의과대학 이비인후과학교실)
  • Received : 2017.09.19
  • Accepted : 2017.10.22
  • Published : 2017.11.30
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Abstract

Langerhans cell histiocytosis (LCH) is a heterogeneous disease, characterized by accumulation of dendritic cells with features similar to epidermal Langerhans cells. It is a rare entity that may involve various organ levels such as the skeletal, pulmonary, hematopoietic and lympho-vascular systems. The patient was a 1-year-old female presented with fever associated with otorrhea and palpable cervical lymph node for 4 days. Neck ultrasonography and Computed tomography imaging revealed multiple enlarged lymph nodes suggesting suspicious malignant morphology. Lymph node biopsy was performed under general anesthesia. Histological and immunophenotypic examination showed the lymph node to be consistent with LCH. The patient was given chemotherapy.

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References

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