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Comparison of Setup Deviations for Two Thermoplastic Immobilization Masks in Glottis Cancer

성문암 세기변조방사선치료에서 두 가지 열가소성 마스크에 대한 환자위치잡이 오차 평가

  • Jung, Jae Hong (Department of Biomedical Engineering, College of Medicine, The Catholic University)
  • 정재홍 (가톨릭대학교의과대학, 생체의공학교실)
  • Received : 2017.02.08
  • Accepted : 2017.03.20
  • Published : 2017.03.31

Abstract

The purpose of this study was compare to the patient setup deviation of two different type thermoplastic immobilization masks for glottis cancer in the intensity-modulated radiation therapy (IMRT). A total of 16 glottis cancer cases were divided into two groups based on applied mask type: standard or alternative group. The mean error (M), three-dimensional setup displacement error (3D-error), systematic error (${\Sigma}$), random error (${\sigma}$) were calculated for each group, and also analyzed setup margin (mm). The 3D-errors were $5.2{\pm}1.3mm$ and $5.9{\pm}0.7mm$ for the standard and alternative groups, respectively; the alternative group was 13.6% higher than the standard group. The systematic errors in the roll angle and the x, y, z directions were $0.8^{\circ}$, 1.7 mm, 1.0 mm, and 1.5 mm in the alternative group and $0.8^{\circ}$, 1.1 mm, 1.8 mm, and 2.0 mm in the alternative group. The random errors in the x, y, z directions were 10.9%, 1.7%, and 23.1% lower in the alternative group than in the standard group. However, absolute rotational angle (i.e., roll) in the alternative group was 12.4% higher than in the standard group. For calculated setup margin, the alternative group in x direction was 31.8% lower than in standard group. In contrast, the y and z direction were 52.6% and 21.6% higher than in the standard group. Although using a modified thermoplastic immobilization mask could be affect patient setup deviation in terms of numerical results, various point of view for an immobilization masks has need to research in terms of clinic issue.

본 연구는 세기변조방사선 치료기술을 이용한 성문암 환자에게 사용되는 두 가지 상이한 열가소성 고정기구 마스크로 인한 환자위치잡이 오차를 비교 평가하고 자 하였다. 치료가 종료된 총 16명의 성문암 환자를 두 그룹으로 나누었고(기존마스크 vs. 변형마스크), 평균, 3D오차, 시스템과 랜덤오차를 구하여 환자위치잡이 오차를 비교하였다. 또한, 치료계획종양체적(PTV)에 대한 여백(margin)을 분석하였다. 3D오차에 대하여 기존 그룹은 $5.2{\pm}1.3mm$고, 변형그룹은 $5.9{\pm}0.7mm$로써, 변형마스크가 변형보다 13.6% 높았다. 시스템오차는 기존그룹(변형그룹)에서 좌표 x, y, z방향은 각각 1.7 mm (1.1 mm), 1.0 mm (1.8 mm), 1.5 mm (2.0 mm)였고, 회전각(roll angle)은 $0.8^{\circ}$ ($0.8^{\circ}$)였다. 랜덤오차는 변형그룹이 기존그룹에 비하여 좌표 x, y, z방향으로 10.9%, 1.7%, 23.1%로 낮았으나, 회전각은 12.4% 높았다. PTV여백에서 변형그룹은 좌표 x방향에 대하여 기존그룹에 비하여 31.8% 낮았으나, 반대로 좌표 y와 z방향에서는 기존그룹보다 각각 52.6%와 21.6%로 높았다. 성문암 세기변조방사선치료에서 변형된 마스크 사용은 고정기구의 변형으로 인한 환자위치잡이 오차는 수치적으로는 영향을 줄 수 있지만, 다양한 관점에서 고정기구 마스크에 대한 연구가 임상적인 측면에서 연구가 필요할 것으로 사료된다.

Keywords

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