한국식품영양학회지 (The Korean Journal of Food And Nutrition)

  • 제30권6호
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  • Pages.1332-1340
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  • 2017
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  • 1225-4339(pISSN)
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  • 2287-4992(eISSN)
한국식품영양학회 (The Korean Society of Food and Nutrition)
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채취시기별 보검선인장 줄기의 항산화, 항당뇨 및 항알츠하이머 활성평가

Antioxidant and Anti-Diabetic, Anti-Alzheimer Activities of Stem from Opuntia ficus-indica var. saboten Cultivated in Jeju at Harvest Time

  • 정윤숙 (농촌진흥청 국립농업과학원 농식품자원부) ;
  • 황병순 (농촌진흥청 국립농업과학원 농식품자원부) ;
  • 조수묵 (농촌진흥청 국립농업과학원 농식품자원부) ;
  • 황경아 (농촌진흥청 국립농업과학원 농식품자원부) ;
  • 황인국 (농촌진흥청 국립농업과학원 농식품자원부)
  • Jeong, Yun Sook (Dept. of Agrofood Resources, National Academy of Agricultural Science, Rural Development Administration) ;
  • Hwang, Byung Soon (Dept. of Agrofood Resources, National Academy of Agricultural Science, Rural Development Administration) ;
  • Cho, Soo-Muk (Dept. of Agrofood Resources, National Academy of Agricultural Science, Rural Development Administration) ;
  • Hwang, Kyung-A (Dept. of Agrofood Resources, National Academy of Agricultural Science, Rural Development Administration) ;
  • Hwang, In Guk (Dept. of Agrofood Resources, National Academy of Agricultural Science, Rural Development Administration)
  • 투고 : 2017.10.16
  • 심사 : 2017.11.17
  • 발행 : 2017.12.31
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초록

In this study, we assessed antioxidant, anti-diabetic, and anti-Alzheimer activities of Opuntia ficus-indica var. saboten (OFI) at harvest time. OFIs were cultivated December 2015~November 2016 in Jeju island. The 70% ethanol extracts of OFI were used to investigate total polyphenol and flavonoid contents, antioxidant(DPPH and ABTS radical scavenging assay), anti-diabetic(yeast ${\alpha}$-glucosidase and rat ${\alpha}$-glucosidase inhibition assay), and anti-Alzheimer(Acetylcholinesterase and butyrylcholinesterase inhibition assay) activities. Total polyphenol and flavonoid contents of OFIs were $17.40{\sim}23.11{\mu}g$ garlic acid/mg Ex and 2.17~6.22 ug (+)-catechine/mg Ex, respectively. DPPH and ABTS radical scavenging activity of OFIs were 131.98~184.90 mg ascorbic acid(AA) eq/100 g and 63.60~101.83 mg AA eq/100 g, respectively. In the anti-diabetic and anti-Alzheimer activities, 70% ethanol extracts of OFI exhibited moderate inhibition activity, compared to control (acarbose and beberine). Total polyphenol and flavonoid contents, antioxidant, anti-diabetic, and anti-Alzheimer activities were no significant differences by season, respectively. Therefore, information on comparative biological evaluations of OFI may be a beneficial in exploring functional food and drug development.

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