대한후두음성언어의학회지 (Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics)

  • 제28권2호
  • /
  • Pages.123-127
  • /
  • 2017
  • /
  • 2508-268X(pISSN)
  • /
  • 2508-5603(eISSN)
대한후두음성언어의학회 (The Korean Society of Laryngology, Phoniatrics and Logopedics. )
권호 표지

접촉성 육아종에서 양성자 펌프 억제제의 치료 효과

Effectiveness of Proton Pump Inhibitor in the Treatment of Contact Granuloma

  • 김동환 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 김건호 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 정선민 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 송창면 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 지용배 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 태경 (한양대학교 의과대학 이비인후-두경부외과학교실)
  • Kim, Dong Hwan (Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Kim, Keon Ho (Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Jung, Seon Min (Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Song, Chang Myeon (Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Ji, Yong Bae (Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Tae, Kyung (Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine)
  • 투고 : 2017.10.31
  • 심사 : 2017.11.13
  • 발행 : 2017.12.30
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초록

Background and Objectives : Contact granuloma is granulation tissue that occurs mainly in the vocal process of arytenoid cartilage. Among several etiological factors, gastric acid reflux is known to be an important cause. The aim of this study was to evaluate clinical characteristics of contact granuloma and analyze the effectiveness of proton pump inhibitor in the treatment of contact granuloma. Materials and Methods : We retrospectively reviewed the medical records of 40 patients who were treated with proton pump inhibitor (PPI) for contact granuloma from January 2011 to December 2015. Reflux finding score (RFS), reflux symptom index (RSI) and size of granuloma were evaluated before and after treatment serially to assess the effectiveness of proton pump inhibitor. Results : Of 40 patients, 25 patients (62.5%) and 10 patients (25%) showed improvement and partial improvement of granuloma, respectively. Five patients showed no response. The mean times of partial improvement and improvement were $2.08{\pm}2.23$ months and $4.60{\pm}2.77$ months, respectively and mean duration of PPI treatment was $6.8{\pm}5.2$ months. Conclusion : Proton pump inhibitors is effective in the treatment of contact granuloma.

키워드

참고문헌

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