Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Electrochemical Non-Enzymatic Glucose Sensor based on Hexagonal Boron Nitride with Metal-Organic Framework Composite

  • Ranganethan, Suresh (Graduate Department of Chemical Materials, Pusan National University) ;
  • Lee, Sang-Mae (Engineering Research Center for Net Shape and Die Manufacturing, Pusan National University) ;
  • Lee, Jaewon (College of Pharmacy, Molecular Inflammation Research Center for Aging Intervention, Pusan National University) ;
  • Chang, Seung-Cheol (Institute of BioPhysio Sensor Technology, Pusan National University)
  • Received : 2017.09.21
  • Accepted : 2017.11.28
  • Published : 2017.11.30
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Abstract

In this study, an amperometric non-enzymatic glucose sensor was developed on the surface of a glassy carbon electrode by simply drop-casting the synthesized homogeneous suspension of hexagonal boron nitride (h-BN) nanosheets with a copper metal-organic framework (Cu-MOF) composite. Comprehensive analytical methods, including field-emission scanning electron microscopy (FE-SEM), Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), cyclic voltammetry, electrochemical impedance spectroscopy, and amperometry, were used to investigate the surface and electrochemical characteristics of the h-BN-Cu-MOF composite. The FE-SEM, FT-IR, and XRD results showed that the h-BN-Cu-MOF composite was formed successfully and exhibited a good porous structure. The electrochemical results showed a sensor sensitivity of $18.1{\mu}A{\mu}M^{-1}cm^{-2}$ with a dynamic linearity range of $10-900{\mu}M$ glucose and a detection limit of $5.5{\mu}M$ glucose with a rapid turnaround time (less than 2 min). Additionally, the developed sensor exhibited satisfactory anti-interference ability against dopamine, ascorbic acid, uric acid, urea, and nitrate, and thus, can be applied to the design and development of non-enzymatic glucose sensors.

Keywords

References

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