참고문헌
- Senior RM, Shapiro SD. Chronic obstructive pulmonary disease: epidemiology, pathophysiology, and pathogenesis. In: Fishman AP, Elias JA, Fishman JA, Grippi MA, Kaiser LR, Senior RM, editors. Fishman's pulmonary diseases and disorders. 3rd ed. New York: McGraw-Hill, Inc.; 1998. p. 659-81.
- Hogg JC, Timens W. The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol 2009;4:435-59. https://doi.org/10.1146/annurev.pathol.4.110807.092145
- Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global burden of disease and risk factors. Washington DC: The International Bank for Reconstruction and Development/The World Bank Group; 2006.
- Nunnari J, Suomalainen A. Mitochondria: in sickness and in health. Cell 2012;148:1145-59. https://doi.org/10.1016/j.cell.2012.02.035
- Eriksson S. Pulmonary emphysema and alpha1-antitrypsin deficiency. Acta Med Scand 1964;175:197-205.
- MacNee W. Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005;2:50-60. https://doi.org/10.1513/pats.200411-056SF
- Larsson K. Aspects on pathophysiological mechanisms in COPD. J Intern Med 2007;262:311-40. https://doi.org/10.1111/j.1365-2796.2007.01837.x
- Fischer BM, Pavlisko E, Voynow JA. Pathogenic triad in COPD: oxidative stress, protease-antiprotease imbalance, and inflammation. Int J Chron Obstruct Pulmon Dis 2011;6:413-21.
- Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007;176:532-55. https://doi.org/10.1164/rccm.200703-456SO
- Niewoehner DE, Kleinerman J, Rice DB. Pathologic changes in the peripheral airways of young cigarette smokers. N Engl J Med 1974;291:755-8. https://doi.org/10.1056/NEJM197410102911503
- Lee SH, Goswami S, Grudo A, Song LZ, Bandi V, Goodnight-White S, et al. Antielastin autoimmunity in tobacco smokinginduced emphysema. Nat Med 2007;13:567-9. https://doi.org/10.1038/nm1583
- Cosio MG, Saetta M, Agusti A. Immunologic aspects of chronic obstructive pulmonary disease. N Engl J Med 2009;360:2445-54. https://doi.org/10.1056/NEJMra0804752
- Brusselle GG, Joos GF, Bracke KR. New insights into the immunology of chronic obstructive pulmonary disease. Lancet 2011;378:1015-26. https://doi.org/10.1016/S0140-6736(11)60988-4
- Kang MJ, Choi JM, Kim BH, Lee CM, Cho WK, Choe G, et al. IL-18 induces emphysema and airway and vascular remodeling via IFN-gamma, IL-17A, and IL-13. Am J Respir Crit Care Med 2012;185:1205-17. https://doi.org/10.1164/rccm.201108-1545OC
- Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, et al. IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation. J Immunol 2007;178:1948-59. https://doi.org/10.4049/jimmunol.178.3.1948
- Dima E, Koltsida O, Katsaounou P, Vakali S, Koutsoukou A, Koulouris NG, et al. Implication of interleukin (IL)-18 in the pathogenesis of chronic obstructive pulmonary disease (COPD). Cytokine 2015;74:313-7. https://doi.org/10.1016/j.cyto.2015.04.008
- Fischer BM, Voynow JA, Ghio AJ. COPD: balancing oxidants and antioxidants. Int J Chron Obstruct Pulmon Dis 2015;10:261-76.
- Tuder RM, Yoshida T, Arap W, Pasqualini R, Petrache I. State of the art: cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective. Proc Am Thorac Soc 2006;3:503-10. https://doi.org/10.1513/pats.200603-054MS
- Yoshida T, Tuder RM. Pathobiology of cigarette smokeinduced chronic obstructive pulmonary disease. Physiol Rev 2007;87:1047-82. https://doi.org/10.1152/physrev.00048.2006
- Imai K, Mercer BA, Schulman LL, Sonett JR, D'Armiento JM. Correlation of lung surface area to apoptosis and proliferation in human emphysema. Eur Respir J 2005;25:250-8. https://doi.org/10.1183/09031936.05.00023704
- Lopez-Otin C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell 2013;153:1194-217. https://doi.org/10.1016/j.cell.2013.05.039
- Kirkwood TB. Understanding the odd science of aging. Cell 2005;120:437-47. https://doi.org/10.1016/j.cell.2005.01.027
- Fukuchi Y. The aging lung and chronic obstructive pulmonary disease: similarity and difference. Proc Am Thorac Soc 2009;6:570-2. https://doi.org/10.1513/pats.200909-099RM
- Lowery EM, Brubaker AL, Kuhlmann E, Kovacs EJ. The aging lung. Clin Interv Aging 2013;8:1489-96.
- Mercado N, Ito K, Barnes PJ. Accelerated ageing of the lung in COPD: new concepts. Thorax 2015;70:482-9. https://doi.org/10.1136/thoraxjnl-2014-206084
- Holloway RA, Donnelly LE. Immunopathogenesis of chronic obstructive pulmonary disease. Curr Opin Pulm Med 2013;19:95-102. https://doi.org/10.1097/MCP.0b013e32835cfff5
- Scheffler IE. Mitochondria. 2nd ed. Hoboken: Wiley-Liss; 2007.
- West AP, Shadel GS, Ghosh S. Mitochondria in innate immune responses. Nat Rev Immunol 2011;11:389-402. https://doi.org/10.1038/nri2975
- Weinberg SE, Sena LA, Chandel NS. Mitochondria in the regulation of innate and adaptive immunity. Immunity 2015;42:406-17. https://doi.org/10.1016/j.immuni.2015.02.002
- Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell 2005;120:483-95. https://doi.org/10.1016/j.cell.2005.02.001
- Cloonan SM, Choi AM. Mitochondria in lung disease. J Clin Invest 2016;126:809-20. https://doi.org/10.1172/JCI81113
- Strowig T, Henao-Mejia J, Elinav E, Flavell R. Inflammasomes in health and disease. Nature 2012;481:278-86. https://doi.org/10.1038/nature10759
- Davis BK, Wen H, Ting JP. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol 2011;29:707-35. https://doi.org/10.1146/annurev-immunol-031210-101405
- Schroder K, Tschopp J. The inflammasomes. Cell 2010;140:821-32. https://doi.org/10.1016/j.cell.2010.01.040
- Yoon CM, Nam M, Oh YM, Dela Cruz CS, Kang MJ. Mitochondrial regulation of inflammasome activation in chronic obstructive pulmonary disease. J Innate Immun 2016;8:121-8. https://doi.org/10.1159/000441299
- Murphy MP. How mitochondria produce reactive oxygen species. Biochem J 2009;417:1-13. https://doi.org/10.1042/BJ20081386
- Galluzzi L, Kepp O, Kroemer G. Mitochondria: master regulators of danger signalling. Nat Rev Mol Cell Biol 2012;13:780-8. https://doi.org/10.1038/nrm3479
- Shadel GS, Horvath TL. Mitochondrial ROS signaling in organismal homeostasis. Cell 2015;163:560-9. https://doi.org/10.1016/j.cell.2015.10.001
- Murphy MP. Modulating mitochondrial intracellular location as a redox signal. Sci Signal 2012;5:pe39.
- Bhola PD, Letai A. Mitochondria-judges and executioners of cell death sentences. Mol Cell 2016;61:695-704. https://doi.org/10.1016/j.molcel.2016.02.019
- Galluzzi L, Bravo-San Pedro JM, Kroemer G. Organelle-specific initiation of cell death. Nat Cell Biol 2014;16:728-36. https://doi.org/10.1038/ncb3005
- Seth RB, Sun L, Ea CK, Chen ZJ. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005;122:669-82. https://doi.org/10.1016/j.cell.2005.08.012
- Kang MJ, Lee CG, Lee JY, Dela Cruz CS, Chen ZJ, Enelow R, et al. Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice. J Clin Invest 2008;118:2771-84.
- Kang MJ, Yoon CM, Kim BH, Lee CM, Zhou Y, Sauler M, et al. Suppression of NLRX1 in chronic obstructive pulmonary disease. J Clin Invest 2015;125:2458-62. https://doi.org/10.1172/JCI71747
- Chang CH, Curtis JD, Maggi LB Jr, Faubert B, Villarino AV, O'Sullivan D, et al. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 2013;153:1239-51. https://doi.org/10.1016/j.cell.2013.05.016
- Sena LA, Li S, Jairaman A, Prakriya M, Ezponda T, Hildeman DA, et al. Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling. Immunity 2013;38:225-36. https://doi.org/10.1016/j.immuni.2012.10.020
- Arnoult D, Soares F, Tattoli I, Castanier C, Philpott DJ, Girardin SE. An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix. J Cell Sci 2009;122(Pt 17):3161-8. https://doi.org/10.1242/jcs.051193
- Arnoult D, Soares F, Tattoli I, Girardin SE. Mitochondria in innate immunity. EMBO Rep 2011;12:901-10. https://doi.org/10.1038/embor.2011.157
- Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, et al. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature 2008;451:573-7. https://doi.org/10.1038/nature06501
- Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, et al. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NFkappaB signaling pathways. Immunity 2011;34:854-65. https://doi.org/10.1016/j.immuni.2011.03.026
- Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, et al. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity 2012;36:933-46. https://doi.org/10.1016/j.immuni.2012.03.025
- Koblansky AA, Truax AD, Liu R, Montgomery SA, Ding S, Wilson JE, et al. The innate immune receptor NLRX1 functions as a tumor suppressor by reducing colon tumorigenesis and key tumor-promoting signals. Cell Rep 2016;14:2562-75. https://doi.org/10.1016/j.celrep.2016.02.064
- Vlahos R, Bozinovski S. Role of alveolar macrophages in chronic obstructive pulmonary disease. Front Immunol 2014;5:435.
- Davies LC, Jenkins SJ, Allen JE, Taylor PR. Tissue-resident macrophages. Nat Immunol 2013;14:986-95. https://doi.org/10.1038/ni.2705
- Byrne AJ, Mathie SA, Gregory LG, Lloyd CM. Pulmonary macrophages: key players in the innate defence of the airways. Thorax 2015;70:1189-96. https://doi.org/10.1136/thoraxjnl-2015-207020
- Thepen T, Van Rooijen N, Kraal G. Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice. J Exp Med 1989;170:499-509. https://doi.org/10.1084/jem.170.2.499
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