Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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Malignant melanoma in a grey pony, Korea

회색 조랑말에서 발생한 악성 흑색종 증례

  • Kim, Ji-Hyeon (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Lee, Hyunkyoung (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Lee, Kyunghyun (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Baek, Kanghyun (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Choi, Eunjin (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • So, ByungJae (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Yang, Siyeon (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency)
  • 김지현 (농림축산검역본부 질병진단과) ;
  • 이현경 (농림축산검역본부 질병진단과) ;
  • 이경현 (농림축산검역본부 질병진단과) ;
  • 백강현 (농림축산검역본부 질병진단과) ;
  • 최은진 (농림축산검역본부 질병진단과) ;
  • 소병재 (농림축산검역본부 질병진단과) ;
  • 양시연 (농림축산검역본부 질병진단과)
  • Received : 2016.07.08
  • Accepted : 2016.09.20
  • Published : 2016.09.30
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Abstract

A 16 year-old female grey pony was presented to Animal and Plant Quarantine agency for diagnosis in Feb 2, 2015. At necropsy, multiple pigmented masses, likely melanomas, were detected peri-anally and under the tail. Further metastatic spread to the spleen, liver, lung and lymph nodes was also identified. Histopathologically, anaplastic and pleomorphic melanocytes were observed in the mass. By immunohistochemistry, PNL2, S100 and PGP 9.5 protein were detected, but Melan A was not expressed in the neoplastic melanocytes. Based on the pathological and immunohistochemical examination, we diagnosed this case as malignant melanoma in a grey pony. To the authors' knowledge, this is the first report of equine malignant melanoma in republic of Korea.

Keywords

References

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