Journal of Digital Convergence (디지털융복합연구)

The Society of Digital Policy and Management (한국디지털정책학회)
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Convergence Studies Vascular Relaxation and Safty Evaluation in Viscum Coloratumma, Chrysantheum Morifolium, Citri Percarpium, and Ophiopoginis Radix Mixture

상기생, 진피, 국화, 맥문동 혼합물의 혈관이완 활성 및 안전성에 관한 융복합 연구

  • Kim, Min-Sook (Dept. of Diets & Health Care, Graduate School of Industry, Myongji University) ;
  • Park, Sung-Hye (Dept. of Food and Nutrition Kwangju Women's University) ;
  • Park, Hae-Ryoung (Division of Liberal Arts & Teacher Training, Kwangju Women's University)
  • 김민숙 (명지대학교 산업대학원 식품양생학과) ;
  • 박성혜 (광주여자대학교 식품영양학과) ;
  • 박해령 (광주여자대학교 교양교직과정부)
  • Received : 2016.08.02
  • Accepted : 2016.09.20
  • Published : 2016.09.28
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Abstract

This study was designed to secure the basis for developing the health tea that may help promote healthy blood vessels by natural herbal ingredients formulated in accordance with the basic principles of oriental medicinal materials. We investigated the vessels contracted by concentrations and safety assessment carried out by the cell viability of Taraaci Herba, Cnidii Rhizoma, Citri Percarpium, and Ophiopoginis Radix composition and concentration. We found cell survival rate was higher than the control group, showing a beneficial trend in the growth of normal liver and kidney cells. As a result, this study will be the basis to develop the health tea differentiated in the future Chinese medicine resources. Medicinal resources will be health tea based on clinical trials utilizing herbal western and oriental medicine convergence principle and vascular relaxation mechanism. And this study tried to make health tea industrialization possible.

본 연구는 상기생, 진피, 국화 및 맥문동 혼헙물이 혈관건강을 증진 시킬 수 있는 건강차를 개발하는데 기초 자료를 확보하고자 한다. 이에 따라 상기생, 진피, 국화 및 맥문동의 혼합 조성물이 농도별로 수축혈관에 미치는 영향과 농도에 따른 조성물이 세포생존율에 미치는 영향을 통해 안정성을 검증하였다. 조성물의 농도가 높을수록 혈관의 이완효과가 큰 것으로 나타났으며, 본 조성물이 혈관의 수축 이완에 영향을 미칠 수 있음을 확인하였다. 또한 세포생존율이 대조군보다 높게 나타나 정상 간과 신장 세포의 성장에 유익한 경향을 보임을 알 수 있었다. 본 연구의 결과는 향후 한약자원을 활용한 차별화된 건강차 개발의 기초자료이며, 개발된 차로 혈관 수축률 억제 기전연구가 이루어진다면 동양의 한약자원을 활용한 현대화된 분석법을 통해 융복합적 방법으로 건강차 개발에 기초자료로 제공하고자 한다.

Keywords

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