A Polyoxygenated Ellagitannin from Cercidiphyllum japonicum Bark

  • Lee, Min-Sung (Department of Forest Biomaterials Engineering, College of Forest and Environment Sciences, Kangwon National University) ;
  • Min, Hee-Jeong (Department of Forest Biomaterials Engineering, College of Forest and Environment Sciences, Kangwon National University) ;
  • Kim, Jin-Kyu (Bio-Center, Gyeonggi Institute of Science & Technology Promotion) ;
  • Bae, Young-Soo (Department of Forest Biomaterials Engineering, College of Forest and Environment Sciences, Kangwon National University)
  • Received : 2016.06.01
  • Accepted : 2016.07.07
  • Published : 2016.07.25


Katsura tree (Cercidiphyllum japonicum Sieb. Et Zucc) bark was collected, air-dried and extracted with 70% aqueous acetone, then concentrated and sequentially fractionated using n-hexane, methylene chloride ($CH_2Cl_2$), ethylacetate (EtOAc), and $H_2O$. The $H_2O$ fraction was chromatographed on a Sephadex LH-20 column with various aqueous MeOH eluting solvents to isolate an ellagitannin. The isolate was elucidated as macabarterin, a polyoxygenated ellagitannin by NMR analysis, including HSQC, HMBC, Q-TOF MS, and with the comparison of authentic literature data. The compound was an ellagitannin which was isolated, for the first time, from the extracts of Katsura tree bark, and has never been reported before in domestic tree or plant sources.



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