Rapid Communication in Photoscience

  • 제5권1호
  • /
  • Pages.11-12
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  • 2016
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  • 2234-8182(pISSN)
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  • 2288-4564(eISSN)
한국광과학회 (Korean Society of Photoscience)
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Induction of Demyelination by Infection of Semliki Forest Virus

  • Kim, Hyun Joo (Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine) ;
  • Choi, Chang-Shik (Department of Food and Fermentation, Far East University) ;
  • Hong, Seong-Karp (Division of Bio and Health Sciences, Mokwon University)
  • 투고 : 2016.03.31
  • 심사 : 2016.04.14
  • 발행 : 2016.06.30
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초록

Schwann cells and neuronal cells from dorsal root ganglion (DRG) in embryos of rat were cultured in vitro respectively. The purified neuronal cells with anti-mitotic agents and purified Schwann cells were co-cultured and then accomplished myelination processing. Infection of Semliki forest virus into this myelinated co-culture system was performed and then accomplished demyelination. We identified myelination and demyelination processing using antibody of neuropeptide Y.

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참고문헌

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